UNC Charlotte Search Results

MURDOCK-NCRC Seed Funding Voucher Awardees

The MURDOCK Study has awarded six $10,000 vouchers as part of the MURDOCK-NCRC Seed Funding Voucher Program to investigators from North Carolina Research Campus partners. Duke University and the MURDOCK Study are pleased to announce the following voucher recipients: Saroja Voruganti, PhD, UNC Nutrition Research Institute (UNC NRI) “A pilot study to identify polymorphisms associated […]

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UNC System President Margaret Spellings Visits the NC Research Campus

            On Monday, March 14, UNC system President Margaret Spellings visited the NC Research Campus as part of her “100 Days” tour. Along with the NC Research Campus, she is visiting all 16 public universities, the NC School of Science and Mathematics and UNC Health Care to “learn and experience […]

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Students try their hand at science

By Erin Weeks Read the original story in the Independent Tribune. Puckered lips and screwed-up faces quickly turned into wide-eyed smiles as lemons the students tasted hit their tongues sweet instead of sour. Protein from a particular frozen berry they’d eaten minutes before altered their taste buds, the 12 middle and high schoolers learned, before […]

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Charlotte Venture Challenge Accepting Appplications

  Applications for the 15th Annual Charlotte Venture Challenge (CVC) business innovation competition are being accepted. The competition is open to early-stage and student ventures from the Southeast. Applications are due March 3. The competition culminates on April 19, 2016 at the beautiful North Carolina Research Campus in Kannapolis, NC. The event will feature finalist pitches to investors […]

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The NCRC Opens New Ready-to-Use Laboratory Suites and First Flexible Office

  Kannapolis, NC– Entrepreneurs take note. The NC Research Campus (NCRC) newest ready-to-use wet laboratory suites and its first flexible office space are both open for business. Located on the third floor of the NCRC’s David H. Murdock Core Laboratory Building both of the new 2,000-square-foot research laboratory suites can be sub-divided into smaller units. […]

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NC bond big for Rowan-Cabarrus, UNC-Charlotte

By Erin Weeks Read the original article in the Independent Tribune. KANNAPOLIS – Rowan and Cabarrus county communities rallied together in support of a statewide bond initiative—the first of its kind in 15 years—pledging support for the initiative that would bring funding for North Carolina’s university and community college systems as well as other public […]

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Metabolomics-Based Analysis of Banana and Pear Ingestion on Exercise Performance and Recovery

Metabolomics-Based Analysis of Banana and Pear Ingestion on Exercise Performance and Recovery, Journal of Proteome Research, November 12, 2015. David C. Nieman,*,† Nicholas D. Gillitt,‡ Wei Sha,§ Mary Pat Meaney,† Casey John,† Kirk L. Pappan,# and Jason M. Kinchen# †Human Performance Laboratory, Appalachian State University, North Carolina Research Campus, Kannapolis, North Carolina 28081, United States […]

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Clinical Research Professionals Host Annual Conference at NCRC

         Kannapolis, NC- On Friday, October 30 from 7:30 am to 3:30 pm, the Greater Charlotte Chapter of the Association of Clinical Research Professionals (GCACRP) will hold their annual conference in the David H. Murdock Core Laboratory Building at the NC Research Campus (NCRC) in Kannapolis, NC. This is the first Charlotte […]

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Lessons learned from metabolomics in cystic fibrosis

Lessons learned from metabolomics in cystic fibrosis, Molecular and Cellular Pediatrics 2015, Marianne S. Muhlebach1* and Wei Sha2 1Department Pediatrics, Division Pulmonology, UNC Chapel Hill 430 MacNider, CB 7217, Chapel Hill 27599-7217, NC, USA 2Bioinformatics Services Division, University of North Carolina at Charlotte, Kannapolis 28081, NC, USA Abstract Cystic fibrosis is a mono-genetic multi-system disease; however, respiratory […]

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A Comparison of transgenic and wild type soybean seeds: analysis of transcriptome profiles using RNA-Seq

A Comparison of transgenic and wild type soybean seeds: analysis of transcriptome profiles using RNA-Seq, BMC Biotechnol, 2015 Oct 1, Lambirth KC1, Whaley AM2, Blakley IC3, Schlueter JA4, Bost KL5, Loraine AE6, Piller KJ7. 1Department of Biological Sciences, University of North Carolina at Charlotte, Charlotte, NC, 28223, USA. kclambirth@uncc.edu. 2Department of Bioinformatics and Genomics, University of North Carolina […]

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Rowan-Cabarrus and Community Leaders Discuss Future of College’s Role in Kannapolis

KANNAPOLIS, N.C. — Rowan-Cabarrus Community College Board of Directors, staff and faculty recently gathered with North Carolina Research Campus representatives, the mayor of Kannapolis and community members to discuss the future of Downtown Kannapolis. This discussion centered around the North Carolina Research Campus and Rowan-Cabarrus Community College’s pivotal role in the growth and development of […]

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Duke Energy Contributes $350,000 to NCRC’s P2EP

Wound-healing properties of oats and the nutritional content of cooked versus uncooked broccoli are just two of the research projects David Phillips, district manager with Duke Energy North Carolina, learned about when he visited the NC Research Campus’ (NCRC) Plant Pathways Elucidation Project (P2EP) on Monday, July 13. Phillips presented $100,000 to P2EP. The check […]

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RNA-seq analysis reveals genetic response and tolerance mechanisms to ozone exposure in soybean

RNA-seq analysis reveals genetic response and tolerance mechanisms to Ozone exposure in soybean, BMC Genomics. 2015 Jun 4, Whaley A1, Sheridan J2, Safari S3, Burton A4, Burkey K5, Schlueter J6. Author information 1Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, 9201 University City Blvd, Charlotte, NC, 28223, USA. awhaley9@uncc.edu. 2Department of Bioinformatics and Genomics, University of […]

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P2EP Kicks Off Third “Summer of Science” at NC Research Campus

The third class of the Plant Pathways Elucidation Project (P2EP) kicked off an 11-week summer of science at the NC Research Campus (NCRC). This year’s class will not only work in teams to research crops including broccoli, blueberries, strawberries and oats, they will also be involved in cooking demonstrations and community outreach, engaging the public with […]

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Analysis and Visualization of RNA-Seq Expression Data Using RStudio, Bioconductor, and Integrated Genome Browser

Analysis and Visualization of RNA-Seq Expression Data Using RStudio, Bioconductor, and Integrated Genome Browser, Methods Mol Biol. 2015 Mar, Loraine AE1, Blakley IC, Jagadeesan S, Harper J, Miller G, Firon N. Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, North Carolina Research Campus, Charlotte, NC, USA, aloraine@uncc.edu. Abstract Sequencing costs are falling, but the […]

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NC Research Campus Ready To Go on New Lab and Office Space

          Contact: Clyde Higgs, Vice President of Business Development NC Research Campus partner@ncresearchcampus.net 704-273-1206 NC Research Campus, Kannapolis, NC– Officials at the NC Research Campus (NCRC) in Kannapolis are investing up to $1.5 million in the construction of a third speculative laboratory suite and new, flexible office space on the third […]

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Freshman Gains Insights in Research Stint at David H. Murdock Research Institute

  Freshman chemistry major Brandon Furr has wrapped up a four-month stint as the first UNC Charlotte intern in the In Vitro Sciences Laboratory at David H. Murdock Research Institute, having gained hands-on research experience and clarity about his future. “As I am leaving my internship, I am definitely interested in exploring research further going […]

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Experience a Dynamic Summer of Science as a P2EP Undergraduate Intern

Undergraduate students with an interest in plant research are encouraged to apply for a dynamic summer of science as part of the Plant Pathways Elucidation Project (P2EP) at the NC Research Campus in Kannapolis, a 350-acre life sciences hub dedicated to advancing scientific discoveries and development relating to human health, nutrition and agriculture. P2EP is […]

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Comparisons of computational methods for differential alternative splicing detection using RNA-seq in plant systems

Comparisons of computational methods for differential alternative splicing detection using RNA-seq in plantsystems. BMC Bioinformatics. 2014 Dec 16, Liu R, Loraine AE, Dickerson JA. UNC Charlotte Abstract BackgroundAlternative Splicing (AS) as a post-transcription regulation mechanism is an important application of RNA-seq studies in eukaryotes. A number of software and computational methods have been developed for detecting AS. Most of the methods, however, are designed and tested on animal data, […]

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Analysis of Changes in Diversity and Abundance of the Microbial Community in a Cystic Fibrosis Patient Over a Multi-Year Period.

Analysis of Changes in Diversity and Abundance of the Microbial Community in a Cystic Fibrosis Patient Over a Multi-Year Period. J Clin Microbiol. 2014 Nov 12, Stokell JR1, Gharaibeh RZ2, Hamp TJ3, Zapata MJ3, Fodor AA3, Steck TR4 Department of Biological Sciences, Univ. of North Carolina at Charlotte, Charlotte, NC 28223, USA. 2Bioinformatics Services Division, Department of […]

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Analysis of Changes in Diversity and Abundance of the Microbial Community in a Cystic Fibrosis Patient Over aMulti-Year Period.

Analysis of Changes in Diversity and Abundance of the Microbial Community in a Cystic Fibrosis Patient Over aMulti-Year Period. J Clin Microbiol. 2014 Nov 12, Stokell JR1, Gharaibeh RZ2, Hamp TJ3, Zapata MJ3, Fodor AA3, Steck TR4 1Department of Biological Sciences, Univ. of North Carolina at Charlotte, Charlotte, NC 28223, USA. 2Bioinformatics Services Division, Department of Bioinformatics and Genomics, Univ. of North Carolina at Charlotte, Kannapolis, NC 28081, USA. 3Department of Bioinformatics and […]

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Analysis of pollen-specific alternative splicing in Arabidopsis thaliana via semi-quantitative PCR

Analysis of pollen-specific alternative splicing in Arabidopsis thaliana via semi-quantitative PCR, PeerJ PrePrints, 2014 Nov 6,  April D Estrada, Nowlan H Freese, Ann E Loraine​ Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, Kannapolis, NC. Abstract  Alternative splicing enables a single gene to produce multiple mRNA isoforms by varying splice site selection. In animals, […]

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High-density single nucleotide polymorphism (SNP) array mapping in Brassica oleracea: identification of QTL associated with carotenoid variation in broccoli florets

High-density single nucleotide polymorphism (SNP) array mapping inBrassica oleracea: identification of QTL associated with carotenoid variation in broccoli florets Theoretical and Applied Genetics 14 Aug 2014 Allan F. Brown, Gad G. Yousef, Kranthi K. Chebrolu, Robert W. Byrd, Koyt W. Everhart, Robert W. Reid, Isobel A. P. Parkin, Andrew G. Sharpe, Rebekah Oliver, Ivette Guzman, Eric W. Jackson Department of Horticultural Science, Plants for Human Health Institute, North Carolina […]

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Scientific coalition studies plants’ role in fighting disease

By Hannah Miller View the article as published in the Charlotte Observer. View the article as published in the Raleigh News & Observer. In the worldwide search to learn more about plants’ role in fighting human disease, an unusual coalition has formed at North Carolina Research Campus in Kannapolis. It’s made up of academic and […]

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N.C. Research Campus internship program plants seeds to grow STEM careers

As published on WRAL TechWire.com By Frank Vinluan KANNAPOLIS, N.C. — Allan Brown likens his blueberry research to trying to put together one big jigsaw puzzle. Brown, an applied molecular geneticist with N.C. State University’s Plants for Human Health Institute at the N.C. Research Campus in Kannapolis, has spent several years working on the genomic sequence of the […]

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Intestinal and Systemic Inflammatory Responses Are Positively Associated with Sulfidogenic Bacteria Abundance in High-Fat–Fed Male C57BL/6J Mice

Intestinal and Systemic Inflammatory Responses Are Positively Associated with Sulfidogenic Bacteria Abundance in High-Fat–Fed Male C57BL/6J Mice, The Journal of Nutrition, June 11, 2014. Wan Shen, Patricia G. Wolf, Franck Carbonero, Wei Zhong, Tanya Reid, H. Rex Gaskins, Michael K. McIntosh. Department of Nutrition, University of North Carolina, Greensboro, NC; Institute of Genomic Biology, University of Illinois, Urbana-Champaign, IL; Department of Food Science, […]

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A Novel Catechol-O-Methyltransferase Variant Associated with Human Disc Degeneration.

A Novel Catechol-O-Methyltransferase Variant Associated with Human Disc Degeneration. May 15, 2014 Gruber HE1, Sha W2, Brouwer CR2, Steuerwald N3, Hoelscher GL1, Hanley EN1. Department of Orthopaedic Surgery, Carolinas Medical Center, Charlotte, N.C.; 2. Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, Charlotte, N.C.; 3. Bioinformatics Services Division, North Carolina Research Campus, Kannapolis, N.C.; 4. […]

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Comparison of Culture and Molecular Techniques for Microbial Community Characterization in Infected Necrotizing Pancreatitis

Comparison of Culture and Molecular Techniques for Microbial Community Characterization in Infected Necrotizing Pancreatitis. Journal of Surgical Research. May 9, 2014. Erin M. Hanna, MD1, Timothy J. Hamp, MS2, Iain H. McKillop, PhD1,Farah Bahrani-Mougeot,PhD3, John B. Martinie, MD1, James M. Horton, MD4, David Sindram, MD, PhD1, Raad Z. Gharaibeh,PhD2, 5, Anthony A. Fodor, PhD2, David A. Iannitti, MD1 1Department of Surgery, Carolinas Medical Center, Charlotte, NC; 2Department of Bioinformatics and Genomics, UNC […]

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Local businesses, and NCRC form business to science partnerships

  Link to original article in Business Today There are signs of growth at the NC Research Campus (NCRC). Site development for the new DataChambers regional data center is underway at Loop Road and Biotechnology Lane. The second suite of ready-to-go laboratories in the David H. Murdock Core Laboratory Building is finished and leasing. The […]

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MUC1 enhances neuropilin-1 signaling in pancreatic ductal adenocarcinoma

MUC1 enhances neuropilin-1 signaling in pancreatic ductal adenocarcinoma AACR Annual Meeting 2014; April 5-9, 2014, Ru Zhou1, Jennifer Curry1, Priyanka Grover1, Lopamudra Das  Roy1, TinChung Leung2, and Pinku Mukherjee1 1University of North Carolina, Charlotte, NC; 2Julius L. Chambers Biomedical Biotechnology Research Institute, North Carolina Central University, Kannapolis, NC. Abstract 26: MUC1 enhances neuropilin-1 signaling in pancreatic ductal adenocarcinoma Abstract Pancreatic ductal adenocarcinoma (PDA) […]

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Ready-to-Go Lab Leased, Second in Planning

Published in Opportunities, a quarterly real estate to research newsletter of the NC Research Campus March 31, 2013 In November 2012, officials at the NCRC announced the construction of ready-to-go laboratory space in the David H. Murdock Core Laboratory Building. Four months later, the 1,500-square-foot space is fully leased. A second ready-to-go laboratory is in the […]

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Patterns of simple sequence repeats in cultivated blueberries (Vaccinium sectionCyanococcus spp.) and their use in revealing genetic diversity and population structure

Patterns of simple sequence repeats in cultivated blueberries (Vaccinium sectionCyanococcus spp.) and their use in revealing genetic diversity and population structure. Molecular Breeding. March 2014. Yang Bian, James Ballington, Archana Raja, Cory Brouwer, Robert Reid, Mark Burke, Xinguo Wang, Lisa J. Rowland, Nahla Bassil,  Allan Brown 1. Department of Horticultural Science, North Carolina State University, 2721 Founders Dr., Raleigh, NC, 27695, USA; 2. Plants for Human […]

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Effects of a freeze-dried juice blend powder on exercise-induced inflammation, oxidative stress, and immune function in cyclists

Effects of a freeze-dried juice blend powder on exercise-induced inflammation, oxidative stress, and immune function in cyclists.  Applied Physiology, Nutrition and Metabolism. March 2014. Knab AM, Nieman DC, Gillitt ND, Shanely RA, Cialdella-Kam L, Henson D, Sha W, Meaney MP. Human Performance Laboratory, Appalachian State University, North Carolina Research Campus; Dole Nutrition Research Laboratory, NC Research Campus; UNC Charlotte Bioinformatics Services Division, […]

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NC Charlotte Bioinformatics planning expansion of their NCRC offices

  Link to the original article on Business Today. Cory Brouwer, director of the UNC Charlotte Bioinformatics Research Services Division at the North Carolina  Research Campus, directs projects involving complex biological computations and the management of immense data sets. This fall, he has simple addition at the forefront of his mind. In October, all of […]

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UNC Charlotte Bioinformatics Expanding NCRC Offices

Published in Opportunities, a real estate to research quarterly newsletter of the NC Research Campus September 30, 2013 UNC Charlotte is expanding their 3,000 square-foot office space in the David H. Murdock Research Institute core laboratory with a 1,200-square-foot addition. “We’re looking to expand and add space that is more flexible to set-up cubicles and have […]

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UNC Charlotte Bioinformatics Plans Expansion of NCRC Offices

    Cory Brouwer, PhD, director of the UNC Charlotte Bioinformatics Research Services Division at the NC Research Campus (NCRC), directs projects involving complex biological computations and the management of immense data sets. This fall, he has simple addition at the forefront of his mind. In October, all of the details should be squared away […]

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The Genome-Wide Early Temporal Response of Saccharomyces cerevisiae to Oxidative Stress Induced by Cumene Hydroperoxide

The Genome-Wide Early Temporal Response of Saccharomyces cerevisiae to Oxidative Stress Induced by Cumene Hydroperoxide. PLoS One.  September 20, 2013. Sha W, Martins AM, Laubenbacher R, Mendes P, Shulaev V. Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, Virginia; Bioinformatics Research Division, University of North Carolina at Charlotte, Kannapolis, NC. Abstract Oxidative stress is a well-known biological process that occurs in all […]

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NCRC internships give students a supporting role in creation of knowledge database

Salisbury Post Wayne Hinshaw / for the salisbury postCatawba College student interns at the North Carolina Research Campus work in the General Mills lab studying oats. They are Amber Williamson and Christian Krzykwa. Five Catawba College students spent their summer interning at the North Carolina Research Campus (NCRC) in Kannapolis helping to gather and organize […]

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Update On The North Carolina Research Campus

Charlotte Talks   It was a dark and uncertain time for Kannapolis ten years ago when the historic Pillowtex plant shut down. Since then, the town has seen much change, both physically and economically. The economic downturn a few years ago put a delay in the metamorphosis that Kannapolis was in the process of in […]

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P2EP: The Dynamics of New Biology

By Pete Prunkl, Greater Charlotte Biz, Tuesday, April 1, 2013 Under the header of “Not Your Father’s Biology,” the National Research Council (NRC) issued a report entitled A New Biology for the 21st Century. In it, the writers coined the term “New Biology” to describe the dynamic needed for the life sciences to address some of […]

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N.C. program immerses students in science

AG Professional North Carolina Research Campus  |  Updated: 07/18/2013 An unprecedented partnership of academic and industry organizations at the North Carolina Research Campus has launched a groundbreaking $1.5 million program to engage college students from across the state in a first-of-its-kind education and research endeavor. Called the Plant Pathways Elucidation Project (P2EP), the program teams up university […]

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UNC Charlotte part of $1.5 million N.C. Research Campus project

  UNC Charlotte News July 17, 2013 An unprecedented partnership of academic and industry organizations at the North Carolina Research Campus is launching a $1.5 million program to engage college students from across the state in a first-of-its-kind education and research endeavor – the Plant Pathways Elucidation Project (P2EP). University scientists, industry leaders and college […]

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NC Research Campus launches plant project for college students

  Jennifer Thomas Staff Writer- Charlotte Business Journal Academic and industry partners at the N.C. Research Campus in Kannapolis have launched a $1.5 million initiative to engage college students from across the state in education and research. The program, called the Plant Pathways Elucidation Project, will center on how plants, including fruits and vegetables, benefit […]

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Whole Grains: Maximizing the Potential

UNC Charlotte’s Ann Loraine, PhD, and Research Technician Ivory Clabaugh have achieved something uncommon. They have found a way to grow rice indoors in an NCRC growth room. Their rice research is just one of four programs on campus where scientists are working to improve the nutritional value of grains and maximize their potential to prevent diseases like diabetes […]

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North Carolina Research Campus adds large-scale data center

By Caitlin McCabe The Charlotte Observer Posted: Thursday, Jun. 13, 2013 Kannapolis’ North Carolina Research Campus will soon offer a home to an unusual tenant: a large-scale data center. Winston-Salem-based DataChambers, an information technology services company, announced Wednesday plans to build a 50,000 square-foot data center on the 350-acre Kannapolis campus. DataChambers, which is owned […]

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RNA-Seq of Arabidopsis Pollen Uncovers Novel Transcription and Alternative Splicing

RNA-Seq of Arabidopsis Pollen Uncovers Novel Transcription and Alternative Splicing. Plant Physiology. June 2013. Loraine AE, McCormick S, Estrada A, Patel K, Qin P. Department of Bioinformatics and Genomics, University of North Carolina, Kannapolis. Abstract Pollen grains of Arabidopsis (Arabidopsis thaliana) contain two haploid sperm cells enclosed in a haploid vegetative cell. Upon germination, the […]

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Pathview: an R/Bioconductor package for pathway based data integration and visualization

Pathview: an R/Bioconductor package for pathway based data integration and visualization. Bioinformatics. Epub June 4, 2013. Luo W, Brouwer C. Department of Bioinformatics and Genomics, UNC Charlotte and NC Research Campus. Abstract SUMMARY: Pathview is a novel tool set for pathway-based data integration and visualization. It maps and renders user data on relevant pathway graphs. […]

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Efficient Quantification of the Health-Relevant Anthocyanin and Phenolic Acid Profiles in Commercial Cultivars and Breeding Selections of Blueberries ( Vaccinium spp.).

Efficient Quantification of the Health-Relevant Anthocyanin and Phenolic Acid Profiles in Commercial Cultivars and Breeding Selections of Blueberries ( Vaccinium spp.). Journal of Agricultural Food Chemistry. Epub May 13, 2013. Yousef GG, Brown AF, Funakoshi Y, Mbeunkui F, Grace MH, Ballington JR, Loraine A, Lila MA. Department of Horticultural Science and Department of Food Bioprocessing and […]

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Identification of cytokinin-responsive genes using microarray meta-analysis and RNA-Seq in Arabidopsis.

Identification of cytokinin-responsive genes using microarray meta-analysis and RNA-Seq in Arabidopsis. Plant Physiology. May 2013. Epub Mar 22, 2013. Bhargava A, Clabaugh I, To JP, Maxwell BB, Chiang YH, Schaller GE, Loraine A (UNC Charlotte at the NC Research Campus), Kieber JJ. Department of Biology, University of North Carolina, Chapel Hill, North Carolina. Abstract Cytokinins […]

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Proposed budget cuts to NC Biotech Center could hurt Charlotte

By: Jennifer Thomas, The Charlotte Business Journal Mar 22, 2013, 2:56pm EDT Proposed budget cuts to NC Biotech Center could hurt Charlotte Enlarge Photo The N.C. Biotechnology Center in the Triad is facing deep cuts to its funding in Gov. Pat McCrory’s proposed state budget. Slashing $10 million from the N.C. Biotechnology Center’s annual appropriation […]

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N.C. Research Campus operation lands $5.3M NIH grant

Jennifer Thomas, Staff Writer- Charlotte Business Journal The UNC Chapel Hill Nutrition Research Institute has received a five-year, $5.3 million grant to study fetal-alcohol disorders in South Africa. The funds from the National Institutes of Health’s National Institute on Alcohol Abuse and Alcoholism will support a handful of studies that will explore the effects of […]

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Rapid emergence of a ceftazidime-resistant Burkholderia multivorans strain in a Cystic Fibrosis patient.

Rapid emergence of a ceftazidime-resistant Burkholderia multivorans strain in a Cystic Fibrosis patient. Journal of Cystic Fibrosis. March 2013. Joshua R. Stokell, Raad Z. Gharaibehb, Todd R. Steck. Department of Biology, University of North Carolina at Charlotte, Bioinformatics Services Division, Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, Kannapolis. Abstract Background Burkholderia multivorans […]

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The heterodimerization of platelet-derived chemokines

The heterodimerization of platelet-derived chemokines. Biochimica et Biophysica Acta (BBA)- Proteins and Proteomics. January 2013. James Carlson, Sarah A. Baxter, Didier Dréau, Irina V. Nesmelova. Analytical Sciences Laboratory, David H. Murdock Research Institute and the Department of Biology,  Department of Physics and Optical Science and the Center for Biomedical Engineering and Science, University of North […]

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Q&A with UNCC’s Chancellor Philip Dubois

By: Elizabeth Cooke, Salisbury Post University of North Carolina Charlotte Chancellor Philip L. Dubois. Photo by Jon C. Lakey, Salisbury Post. With enrollment exceeding 26,000 students and applications up 20 percent over last year, the University of North Carolina Charlotte seems light years away from the veterans’ training center that started it all more than […]

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harlotte Forecast 2013: Research & Development

By: Jennifer Thomas, Charlotte Business Journal Research has become a fundamental part of the Charlotte region’s economy. And its presence will take several big steps forward in 2013 — from UNC Charlotte to Johnson C. Smith University to Carolinas HealthCare to the N.C. Research Campus in Kannapolis. All have significant research-oriented initiatives that will grow […]

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Ready-To-Go Lab Space Available

Published in Opportunities, a quarterly real estate to research newsletter of the NC Research Campus November 30, 2012 Construction is starting on ready-to-go lab space that will be available in February 2013. The 1,500-square-foot wet laboratory is the first pre-built, flexible lab space to be constructed at the NCRC since the campus opened four years ago. […]

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Local researchers brace for job cuts if Congress can’t reach deal on fiscal cliff

By Holly Maynard, WSOCTV http://www.wsoctv.com/videos/news/local-researchers-brace-for-job-cuts-if-congress/vhzqB/ KANNAPOLIS, N.C. — Local researchers are bracing for job cuts if Congress doesn’t come to an agreement on the fiscal cliff by the end of the year. Eyewitness News went inside a lab at the North Carolina Research Campus in the heart of Kannapolis. That’s where scientists in the fields […]

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Charlotte conference highlights region’s life-sciences research

By Jeremy Summers, NCBiotech Writer Charlotte is known for its strong financial roots, diverse business climate and   for being the unofficial home of NASCAR. Thanks to new commitments to education and research, the region is also gaining some recognition as a hotbed for cutting edge research and technologies in biotech and other life-sciences industries. […]

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NCRC Focus of UNC Charlotte Life Sciences Conference

Contact: Phyllis Beaver Marketing Director North Carolina Research Campus pbeaver@ncresearchcampus.net www.ncresearchcampus.net   (NC Research Campus, Kannapolis, NC- October 23, 2012)- The North Carolina Research Campus in Kannapolis, a 350-acre life science research center just north of Charlotte, is the focus of the eleventh annual UNC Charlotte Life Sciences Conference. The conference is being held on […]

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Second degree, determination help Bayless land dream job

  KANNAPOLIS – TeQuana Bayless has been a bit of a science nerd her entire life. “I remember in elementary school, my mom bought me a chemistry set so I could grow my own crystals,” she said. “In high school, I worked closely with my microbiology and chemistry teachers.” So, it’s no surprise that she’s […]

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Murdoch Institute will get funding for genome group

KANNAPOLIS – The David H. Murdock Research Institute (DHMRI) announced today that it will receive funding from the North Carolina Biotechnology Center to sponsor the Genomic Sciences Regional Exchange Group (Gene REG) which is designed to focus on genomics-based research. Gene REG will serve as a forum for discussing scientific ideas, new directions and data […]

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Kannapolis Scholars Conference Focuses on the Role of Exercise in Obesity Prevention

  Link to original article The Kannapolis Scholars, a program of N.C. State University at the N.C. Research Campus, is hosting its second conference on how to address the challenges of obesity. “Lost in Translation: A Conversation on Exercise and Obesity” will be held on Friday, July 27, 2012, from 10:15 a.m. to 4 p.m. […]

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Bananas For An Energy Boost

Scientists with the Appalachian State University Human Performance Lab and the Dole Foods Nutrition Research Laboratory published findings in May in the peer-reviewed online journal PloS One that proved scientifically what professional and recreational athletes have long believed- bananas are a good source of energy when exercising. The study showed that bananas provide the same energy boost as […]

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Untitled

By Sarah Campbell, Salisbury Post KANNAPOLIS — While most of Grace Millsap’s classmates at the University of North Carolina at Charlotte will be scrambling to find a job after they graduate in May, she’ll simply be transitioning to a full-time gig. Millsap, who started interning at UNC’s Nutrition Research Institute on the campus of the […]

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Researchers take a closer look at Fetal Alcohol Syndrome

By Katie Scarvey kscarvey@salisburypost.com KANNAPOLIS — So why would a pre-eminent researcher in fetal alcohol spectrum disorders (FASD) end up at the Nutrition Research Institute? It’s a valid question, and Dr. Philip May — who admits that he used to be “nutritionally ignorant” — attempted to answer it recently during an Appetite for Life lecture […]

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Mining Arabidopsis thaliana RNA-seq data with Integrated Genome Browser reveals stress-induced alternative splicing of the putative splicing regulator SR45a.

Mining Arabidopsis thaliana RNA-seq data with Integrated Genome Browser reveals stress-induced alternative splicing of the putative splicing regulator SR45a. American Journal of Botany, February 2012. Gulledge AA, Roberts AD, Vora H, Patel K, Loraine AE. Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, North Carolina Research Campus. Abstract PREMISE OF THE STUDY: […]

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Ryan Dayvault: Young politician brings fresh perspective

Salisbury Post Ryan Dayvault is a young man with an old soul. A novice politician with deep roots in Kannapolis, Dayvault swept the Kannapolis City Council election in November and emerged as the top vote-getter. He won almost 28 percent of total votes. Descended from the man who sold a farm in 1905 that became […]

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A regulon conserved in monocot and dicot plants defines a functional module in antifungal plant immunity.

Humphry A, Pednarek P, Kemmerling B, Koh S, Stein M, Gobel U, Stuber K, Pislewska-Bednarek M, Loraine A, Schulze-Lefert P, Somerville S, Panstruga R. A regulon conserved in monocot and dicot plants defines a functional module in antifungal plant immunity. PNAS 2010, 107(50):21896-901. Abstract BACKGROUND: Around 14% of protein-coding genes of Arabidopsis thaliana genes from […]

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Prevalence of alternative splicing choices in Arabidopsis

English A, Patel K, Loraine AE. Prevalence of alternative splicing choices in Arabidopsis. BMC Plant Biology. BMC Plant Biology 2010, 10:102.PubMed.ArabiTag-alternative splicing data-mining tool. Abstract BACKGROUND: Around 14% of protein-coding genes of Arabidopsis thaliana genes from the TAIR9 genome release are annotated as producing multiple transcript variants through alternative splicing. However, for most alternatively spliced […]

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Consistency analysis of redundant probe sets on Affymetrix three-prime expression arrays and applications to differential mRNA processing

Cui X, Loraine AE. 2009. Consistency analysis of redundant probe sets on Affymetrix three-prime expression arrays and applications to differential mRNA processing. PLoSOne. 2009;4(1):e4229. Epub 2009 Jan 23. PubMed Abstract Affymetrix three-prime expression microarrays contain thousands of redundant probe sets that interrogate different regions of the same gene. Differential expression analysis methods rarely consider probe […]

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Co-expression Analysis of Metabolic Pathways in Plants

Loraine, A. Co-expression Analysis of Metabolic Pathways in Plants. Methods Mol Biol. 2009; 553:247-64.PubMed Abstract Co-expression analysis allows experimenters to re-use archived expression microarray data to uncover previously unknown functional relationships between genes. An observation that a group of genes are co-expressed across diverse experimental conditions suggests they may play similar roles in the cell. […]

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The Integrated Genome Browser: Free software for distribution and exploration of genome-scale data sets.

Nicol JW, Helt GA, Blanchard SG, Raja A, Loraine AE. The Integrated Genome Browser: Free software for distribution and exploration of genome-scale data sets. Bioinformatics. 2009 October 15; 25(20):27302. Article Abstract Experimental techniques that survey an entire genome demand flexible, highly interactive visualization tools that can display new data alongside foundation datasets, such as reference […]

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The Genoviz Software Development Kit: A Java toolkitfor building genomics visualization applications.

Helt GA, Nicol JW, Blossom E, Blanchard S, Chervitz SA, Harmon C, LoraineAE. The Genoviz Software Development Kit: A Java toolkitfor building genomics visualization applications. BMC Bioinformatics. 2009, 10:266. Abstract BACKGROUND: Visualization software can expose previously undiscovered patterns in genomic data and advance biological science. RESULTS: The Genoviz Software Development Kit (SDK) is an open […]

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Assembly of an interactive network for the Arabidopsis genome using a novel heuristic clustering algorithm. Plant Physiol

Mutwil M, Usadel B, Schutte M, Loraine A, Ebenhoh O, Persson S. Assembly of an interactive network for the Arabidopsis genome using a novel heuristic clustering algorithm. Plant Physiol. 2010 Jan;152(1):29-43. Epub 2009 Nov 4.PubMed Abstract A vital quest in biology is comprehensible visualization and interpretation of correlation relationships on a genome scale. Such relationships […]

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Lowering industry firewalls: pre-competitive informatics initiatives in drug discovery.

Barnes M R, Harland L, Foord S M, Hall M D, Dix I, Thomas S, Williams-Jones B I, Brouwer C R. (2009) Lowering industry firewalls: pre-competitive informatics initiatives in drug discovery. Nat Rev Drug Discov. 8:701-708. Abstract Pharmaceutical research and development is facing substantial challenges that have prompted the industry to shift funding from early- […]

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Visualizing the drug target landscape.

Campbell S A, Gaulton A, Marshall J, Bichko D, Martin S, Brouwer C and Harland L. (2009) Visualizing the drug target landscape. Drug Disc Today. 15:3-15. Abstract Generating new therapeutic hypotheses for human disease requires the analysis and interpretation of many different experimental datasets. Assembling a holistic picture of the current landscape of drug discovery […]

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Large-Scale Transposon Mutagenesis of Mycoplasma pulmonis

French CT, Lao P, Loraine AE, Matthews BT, Yu H, Dybvig K. Large-Scale Transposon Mutagenesis of Mycoplasma pulmonis. Mol Microbiol. Mol Microbiol. 2008 Jul;69(1):67-76. Epub 2008 Apr 28. Abstract To obtain mutants for the study of the basic biology and pathogenic mechanisms of mycoplasmas, the insertion site of transposon Tn4001T was determined for 1700 members […]

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Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient.

Yao J, Chang C, Salmi ML, Hung YS, Loraine A, Roux SJ. Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient. BMC Bioinformatics. 2008 Jun 18;9:288. Abstract BACKGROUND: Currently, clustering with some form of correlation coefficient as the gene similarity metric has become a popular method for profiling genomic data. The Pearson correlation coefficient […]

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The Genome of Mycoplasma arthritidis

Dybvig K, Zuhua C, Lao P, Jordan DS, French CT, Tu AH, Loraine AE. The Genome of Mycoplasma arthritidis. Infect Immun. 2008 Jun 23. Abstract The genomes of several species of mycoplasma have been sequenced. Most of these species rely on the glycolytic pathway for energy production, with the one exception of Ureaplasma, a species […]

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CressExpress: A tool for large-scale mining of expression data from Arabidopsis thaliana.

Srinivasasainagendra V, Page G, Mehta T, Coulibaly I, Loraine AE. CressExpress: A tool for large-scale mining of expression data from Arabidopsis thaliana. Plant Physiology. 2008 Jul;147(3):1004-16. Abstract CressExpress is a user-friendly, online, coexpression analysis tool for Arabidopsis (Arabidopsis thaliana) microarray expression data that computes patterns of correlated expression between user-entered query genes and the rest […]

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