UNC Charlotte

NC bond big for Rowan-Cabarrus, UNC-Charlotte

December 04, 2015

By Erin Weeks Read the original article in the Independent Tribune. KANNAPOLIS – Rowan and Cabarrus county communities rallied together in support of a statewide bond initiative—the first of its kind in 15 years—pledging support for the initiative that would bring funding for North Carolina’s university and community college systems as well as other public […]

Lessons learned from metabolomics in cystic fibrosis

October 26, 2015

Lessons learned from metabolomics in cystic fibrosis, Molecular and Cellular Pediatrics 2015, Marianne S. Muhlebach1* and Wei Sha2 1Department Pediatrics, Division Pulmonology, UNC Chapel Hill 430 MacNider, CB 7217, Chapel Hill 27599-7217, NC, USA 2Bioinformatics Services Division, University of North Carolina at Charlotte, Kannapolis 28081, NC, USA Abstract Cystic fibrosis is a mono-genetic multi-system disease; however, respiratory […]

A Comparison of transgenic and wild type soybean seeds: analysis of transcriptome profiles using RNA-Seq

October 01, 2015

A Comparison of transgenic and wild type soybean seeds: analysis of transcriptome profiles using RNA-Seq, BMC Biotechnol, 2015 Oct 1, Lambirth KC1, Whaley AM2, Blakley IC3, Schlueter JA4, Bost KL5, Loraine AE6, Piller KJ7. 1Department of Biological Sciences, University of North Carolina at Charlotte, Charlotte, NC, 28223, USA. kclambirth@uncc.edu. 2Department of Bioinformatics and Genomics, University of North Carolina […]

RNA-seq analysis reveals genetic response and tolerance mechanisms to ozone exposure in soybean

June 04, 2015

RNA-seq analysis reveals genetic response and tolerance mechanisms to Ozone exposure in soybean, BMC Genomics. 2015 Jun 4, Whaley A1, Sheridan J2, Safari S3, Burton A4, Burkey K5, Schlueter J6. Author information 1Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, 9201 University City Blvd, Charlotte, NC, 28223, USA. awhaley9@uncc.edu. 2Department of Bioinformatics and Genomics, University of […]

Analysis and Visualization of RNA-Seq Expression Data Using RStudio, Bioconductor, and Integrated Genome Browser

March 19, 2015

Analysis and Visualization of RNA-Seq Expression Data Using RStudio, Bioconductor, and Integrated Genome Browser, Methods Mol Biol. 2015 Mar, Loraine AE1, Blakley IC, Jagadeesan S, Harper J, Miller G, Firon N. Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, North Carolina Research Campus, Charlotte, NC, USA, aloraine@uncc.edu. Abstract Sequencing costs are falling, but the […]

Comparisons of computational methods for differential alternative splicing detection using RNA-seq in plant systems

December 16, 2014

Comparisons of computational methods for differential alternative splicing detection using RNA-seq in plantsystems. BMC Bioinformatics. 2014 Dec 16, Liu R, Loraine AE, Dickerson JA. UNC Charlotte Abstract BackgroundAlternative Splicing (AS) as a post-transcription regulation mechanism is an important application of RNA-seq studies in eukaryotes. A number of software and computational methods have been developed for detecting AS. Most of the methods, however, are designed and tested on animal data, […]

Analysis of Changes in Diversity and Abundance of the Microbial Community in a Cystic Fibrosis Patient Over a Multi-Year Period.

November 12, 2014

Analysis of Changes in Diversity and Abundance of the Microbial Community in a Cystic Fibrosis Patient Over a Multi-Year Period. J Clin Microbiol. 2014 Nov 12, Stokell JR1, Gharaibeh RZ2, Hamp TJ3, Zapata MJ3, Fodor AA3, Steck TR4 Department of Biological Sciences, Univ. of North Carolina at Charlotte, Charlotte, NC 28223, USA. 2Bioinformatics Services Division, Department of […]

Analysis of Changes in Diversity and Abundance of the Microbial Community in a Cystic Fibrosis Patient Over aMulti-Year Period.

November 12, 2014

Analysis of Changes in Diversity and Abundance of the Microbial Community in a Cystic Fibrosis Patient Over aMulti-Year Period. J Clin Microbiol. 2014 Nov 12, Stokell JR1, Gharaibeh RZ2, Hamp TJ3, Zapata MJ3, Fodor AA3, Steck TR4 1Department of Biological Sciences, Univ. of North Carolina at Charlotte, Charlotte, NC 28223, USA. 2Bioinformatics Services Division, Department of Bioinformatics and Genomics, Univ. of North Carolina at Charlotte, Kannapolis, NC 28081, USA. 3Department of Bioinformatics and […]

Analysis of pollen-specific alternative splicing in Arabidopsis thaliana via semi-quantitative PCR

November 06, 2014

Analysis of pollen-specific alternative splicing in Arabidopsis thaliana via semi-quantitative PCR, PeerJ PrePrints, 2014 Nov 6,  April D Estrada, Nowlan H Freese, Ann E Loraine​ Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, Kannapolis, NC. Abstract  Alternative splicing enables a single gene to produce multiple mRNA isoforms by varying splice site selection. In animals, […]

High-density single nucleotide polymorphism (SNP) array mapping in Brassica oleracea: identification of QTL associated with carotenoid variation in broccoli florets

August 13, 2014

High-density single nucleotide polymorphism (SNP) array mapping inBrassica oleracea: identification of QTL associated with carotenoid variation in broccoli florets Theoretical and Applied Genetics 14 Aug 2014 Allan F. Brown, Gad G. Yousef, Kranthi K. Chebrolu, Robert W. Byrd, Koyt W. Everhart, Robert W. Reid, Isobel A. P. Parkin, Andrew G. Sharpe, Rebekah Oliver, Ivette Guzman, Eric W. Jackson Department of Horticultural Science, Plants for Human Health Institute, North Carolina […]

Intestinal and Systemic Inflammatory Responses Are Positively Associated with Sulfidogenic Bacteria Abundance in High-Fat–Fed Male C57BL/6J Mice

May 17, 2014

Intestinal and Systemic Inflammatory Responses Are Positively Associated with Sulfidogenic Bacteria Abundance in High-Fat–Fed Male C57BL/6J Mice, The Journal of Nutrition, June 11, 2014. Wan Shen, Patricia G. Wolf, Franck Carbonero, Wei Zhong, Tanya Reid, H. Rex Gaskins, Michael K. McIntosh. Department of Nutrition, University of North Carolina, Greensboro, NC; Institute of Genomic Biology, University of Illinois, Urbana-Champaign, IL; Department of Food Science, […]

A Novel Catechol-O-Methyltransferase Variant Associated with Human Disc Degeneration.

May 15, 2014

A Novel Catechol-O-Methyltransferase Variant Associated with Human Disc Degeneration. May 15, 2014 Gruber HE1, Sha W2, Brouwer CR2, Steuerwald N3, Hoelscher GL1, Hanley EN1. Department of Orthopaedic Surgery, Carolinas Medical Center, Charlotte, N.C.; 2. Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, Charlotte, N.C.; 3. Bioinformatics Services Division, North Carolina Research Campus, Kannapolis, N.C.; 4. […]

MUC1 enhances neuropilin-1 signaling in pancreatic ductal adenocarcinoma

April 05, 2014

MUC1 enhances neuropilin-1 signaling in pancreatic ductal adenocarcinoma AACR Annual Meeting 2014; April 5-9, 2014, Ru Zhou1, Jennifer Curry1, Priyanka Grover1, Lopamudra Das  Roy1, TinChung Leung2, and Pinku Mukherjee1 1University of North Carolina, Charlotte, NC; 2Julius L. Chambers Biomedical Biotechnology Research Institute, North Carolina Central University, Kannapolis, NC. Abstract 26: MUC1 enhances neuropilin-1 signaling in pancreatic ductal adenocarcinoma Abstract Pancreatic ductal adenocarcinoma (PDA) […]

Ready-to-Go Lab Leased, Second in Planning

March 31, 2014

Published in Opportunities, a quarterly real estate to research newsletter of the NC Research Campus March 31, 2013 In November 2012, officials at the NCRC announced the construction of ready-to-go laboratory space in the David H. Murdock Core Laboratory Building. Four months later, the 1,500-square-foot space is fully leased. A second ready-to-go laboratory is in the […]

UNC Charlotte Bioinformatics Expanding NCRC Offices

September 30, 2013

Published in Opportunities, a real estate to research quarterly newsletter of the NC Research Campus September 30, 2013 UNC Charlotte is expanding their 3,000 square-foot office space in the David H. Murdock Research Institute core laboratory with a 1,200-square-foot addition. “We’re looking to expand and add space that is more flexible to set-up cubicles and have […]

The Genome-Wide Early Temporal Response of Saccharomyces cerevisiae to Oxidative Stress Induced by Cumene Hydroperoxide

September 20, 2013

The Genome-Wide Early Temporal Response of Saccharomyces cerevisiae to Oxidative Stress Induced by Cumene Hydroperoxide. PLoS One.  September 20, 2013. Sha W, Martins AM, Laubenbacher R, Mendes P, Shulaev V. Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, Virginia; Bioinformatics Research Division, University of North Carolina at Charlotte, Kannapolis, NC. Abstract Oxidative stress is a well-known biological process that occurs in all […]

Update On The North Carolina Research Campus

August 12, 2013

Charlotte Talks   It was a dark and uncertain time for Kannapolis ten years ago when the historic Pillowtex plant shut down. Since then, the town has seen much change, both physically and economically. The economic downturn a few years ago put a delay in the metamorphosis that Kannapolis was in the process of in […]

N.C. program immerses students in science

July 18, 2013

AG Professional North Carolina Research Campus  |  Updated: 07/18/2013 An unprecedented partnership of academic and industry organizations at the North Carolina Research Campus has launched a groundbreaking $1.5 million program to engage college students from across the state in a first-of-its-kind education and research endeavor. Called the Plant Pathways Elucidation Project (P2EP), the program teams up university […]