Slavko Komarnytsky

Alaskan seaweeds lower inflammation in RAW 264.7 macrophages and decrease lipid accumulation in 3T3-L1 adipocytes

April 14, 2015

Alaskan seaweeds lower inflammation in RAW 264.7 macrophages and decrease lipid accumulation in 3T3-L1 adipocytes, 14 Apr 2015, Journal of Functional Foods. Joshua Kellogg, Debora Esposito, Mary H. Grace, Slavko Komarnytsky, Mary Ann Lila NC State University Abstract Chronic inflammation is characterized by macrophage accumulation in adipose tissue, which subsequently up-regulates pro-inflammatory cytokines and promotes the dysregulation of lipid metabolism, […]

Diverse Classes of Bitter Phytochemicals Modulate Carbohydrate Metabolism and Immune Responses through Gastrointestinal Bitter Taste Receptors

April 07, 2015

Diverse Classes of Bitter Phytochemicals Modulate Carbohydrate Metabolism and Immune Responses through Gastrointestinal Bitter Taste Receptors, Apr 2015, The FASEB Journal, Kimberly Palatini1,2, Mickey Wilson1,2, Jessica Alley1,3, Debora Esposito1,2 and Slavko Komarnytsky1,2 1Plants for Human Health Institute North Carolina State University Kannapolis NC United States 2Food, Bioprocessing, and Nutrition Sciences North Carolina State University Raleigh NC United States 3Health and Exercise […]

Pink Slip to Scientist: Rowan-Cabarrus Graduate Researches Bioactive Compounds, Inflammation

May 09, 2013

In 2008, Mickey Wilson knew it was time for a change. His job of 13 years with Freightliner in Cleveland, NC looked like it would be coming to an end as the company laid-off employees and struggled financially. Moving into another quality control job with another company didn’t seem appealing. So he made a decision […]

Boosting Phyto-Benefits for Better Health and Longevity

March 12, 2013

Published in the Charlotte Observer’s Pulse Magazine.  Broccoli, blueberries and bananas are already tagged “super foods” meaning they are more nutritious than most other fruits and vegetables.  Yet, under the microscopes at the North Carolina Research Campus (NCRC) in Kannapolis, scientists are finding ways to boost their benefits. The NCRC is a public-private research center […]

Pregnane glycosides interfere with steroidogenic enzymes to down-regulate corticosteroid production in human adrenocortical H295R cells

October 10, 2012

Pregnane glycosides interfere with steroidogenic enzymes to down-regulate corticosteroid production in human adrenocortical H295R cells. Journal of Cellular Physiology. October 2012. Komarnytsky S, Esposito D, Poulev A, Raskin I. Rutgers University and NC State University Plants for Human Health Institute. Abstract A group of bioactive steroidal glycosides (pregnanes) with anorectic activity in animals was isolated […]

Brassica Breakthroughs

October 09, 2012

Research conducted at the NC State University Plants for Human Health Institute (PHHI) has resulted in a range of findings from the development of a functional food powder to the genome sequencing of the blueberry to recent findings revealing the benefits of plant steroids. Specifically, the brassinosteroid homobrassinolide, which is found in all plants and regulates growth […]

Hypoglycemic effects of brassinosteroid in diet-induced obese mice

September 10, 2012

Hypoglycemic effects of brassinosteroid in diet-induced obese mice. Amerian Journal of Physiology, Endriconology and Metabolism. September 2012. Esposito D, Kizelsztein P, Komarnytsky S, Raskin I. North Carolina State University Plants for Human Health Institute. Abstract The prevalence of obesity is increasing globally, and obesity is a major risk factor for metabolic diseases such as type […]