NC A&T University

Bioactive Ginger Constituents Alleviate Protein Glycation by Trapping Methylglyoxal

August 13, 2015

Bioactive Ginger Constituents Alleviate Protein Glycation by Trapping Methylglyoxal, Chem Res Toxicol. 2015 Aug 13, Zhu Y1, Zhao Y1, Wang P1, Ahmedna M, Sang S1. 1†Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus, 500 Laureate Way, Kannapolis, North Carolina 28081, United States. Abstract Considerable evidence suggests […]

Novel Resveratrol-based Aspirin Prodrugs: Synthesis, Metabolism, and Anticancer Activity

July 23, 2015

Novel Resveratrol-based Aspirin Prodrugs: Synthesis, Metabolism, and Anticancer Activity, J Med Chem. 2015 J Zhu Y, Fu J, Shurlknight K, Soroka D, Hu Y, Chen XL, Sang S. Abstract Regular aspirin use has been convincingly shown to reduce the risk of colorectal cancer. However, long-term use of aspirin leads to gastrotoxicity. Herein, we designed and synthesized […]

Numerical solution of a microbial growth model applied to dynamic environments.

May 23, 2015

Numerical solution of a microbial growth model applied to dynamic environments, 2015 May, J Microbiol Methods,  Zhu S1, Chen G2. 1Center for Excellence in Post-Harvest Technologies, North Carolina A&T State University, The North Carolina Research Campus, 500 Laureate Way, Kannapolis, NC 28081, USA. 2Center for Excellence in Post-Harvest Technologies, North Carolina A&T State University, The North Carolina Research […]

Species authentication and geographical origin discrimination of herbal medicines by near infrared spectroscopy: A review

April 23, 2015

Species authentication and geographical origin discrimination of herbal medicines by near infrared spectroscopy: A review, 23 April 2015,  Journal of Pharmaceutical Analysis, Pei Wanga, b, Zhiguo Yua School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China b Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus, 500 Laureate Way, Kannapolis, […]

Synergistic Effects of Fiber and Phytochemicals in Wheat Bran on Colon Cancer

April 07, 2015

Synergistic Effects of Fiber and Phytochemicals in Wheat Bran on Colon Cancer, Apr 2015, The FASEB Journal, Jennifer McBride1, Yingdong Zhu1, Pei Wang1 and Shengmin Sang1 1Center for Excellence in Post-Harvest Technologies North Carolina Agricultural and Technical State University Kannapolis NC United States Abstract Colorectal cancer (CRC) is a leading cause of cancer related deaths in the United States. Epidemiological […]

Carnosic Acid as the Major Bioactive Component in Rosemary Extract Ameliorates High-fat Diet-induced Obesity and Metabolic Syndrome in Mice

April 07, 2015

Carnosic Acid as the Major Bioactive Component in Rosemary Extract Ameliorates High-fat Diet-induced Obesity and Metabolic Syndrome in Mice, Apr 2015, The FASEB Journal, Yantao Zhao1, Rashin Sedighi1, Pei Wang1, Huadong Chen1, Yingdong Zhu1 and Shengmin Sang1 –1Center for Excellence in Post-Harvest Technologies North Carolina Agricultural and Technical State University Kannapolis NC United States Abstract Rosemary has been used as a natural […]

Oat Avenanthramides Induce Heme Oxygengase-1 Expression via Nrf2-mediated Signaling in HK-2 Cells

April 07, 2015

Oat Avenanthramides Induce Heme Oxygengase-1 Expression via Nrf2-mediated Signaling in HK-2 Cells, Apr 2015, The FASEB Journal, Shengmin Sang1, Junsheng Fu1, Yingdong Zhu1, Aaron Yerke1, Mitchell Wise2, Jodee Johnson3 and YiFang Chu3 1Center for Excellence in Post-Harvest Technologies North Carolina Agricultural and Technical State University Kannapolis NC United States 2Cereal Crops Research Unit USDA Madison WI United States 3Quaker Oats Center of Excellence […]

Explicit modeling of microbial growth under nonisothermal conditions.

March 10, 2015

Explicit modeling of microbial growth under nonisothermal conditions. J Microbiol Methods. 2015 Mar 10, Zhu S1, Chen G2. Center for Excellence in Post-Harvest Technologies, North Carolina A&T State University, The North Carolina Research Campus, 500 Laureate Way, Kannapolis, NC 28081, USA. 2Center for Excellence in Post-Harvest Technologies, North Carolina A&T State University, The North Carolina Research Campus, 500 Laureate Way, Kannapolis, NC 28081, USA. […]

Preventive and Protective Properties of Rosemary (Rosmarinus Officinalis L.) in Obesity and Diabetes Mellitus of Metabolic Disorders: A Brief Review

February 10, 2015

Preventive and Protective Properties of Rosemary (Rosmarinus Officinalis L.) in Obesity and Diabetes Mellitus of Metabolic Disorders: A Brief Review, Current Opinion in Food Science, 10 February 2015,  Rashin Sedighi, Yantao Zhao, Aaron Yerke, Shengmin Sang Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus, 500 Laureate Way, Kannapolis, North Carolina […]

Oat Avenanthramide-C (2c) Is Biotransformed by Mice and the Human Microbiota into Bioactive Metabolites

December 27, 2014

Oat Avenanthramide-C (2c) Is Biotransformed by Mice and the Human Microbiota into Bioactive Metabolites,2015 American Society for Nutrition Dec 2014, Pei Wang4, Huadong Chen4, Yingdong Zhu, Jennifer McBride, Junsheng Fu, and Shengmin Sang* Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus, Kannapolis, NC Oat Avenanthramide-C (2c) Is Biotransformed by Mice and the Human […]

Tea Flavanols Block Advanced Glycation of Lens Crystallins Induced by Dehydroascorbic Acid.

December 01, 2014

Tea Flavanols Block Advanced Glycation of Lens Crystallins Induced by Dehydroascorbic Acid. Chem Res Toxicol. 2014 Dec 1, Zhu Y, Zhao Y, Wang P, Ahmedna M, Ho CT, Sang S. NC A&T University Abstract Growing evidence has shown that ascorbic acid (ASA) can contribute to protein glycation and the formation of advanced glycation end products (AGEs), especially in the lens. The mechanism by which ascorbic acid can cause […]

Quercetin Inhibits Advanced Glycation End Product Formation by Trapping Methylglyoxal and Glyoxal

November 20, 2014

Quercetin Inhibits Advanced Glycation End Product Formation by Trapping Methylglyoxal and Glyoxal. J Agric Food Chem. 2014 Nov 20, Li X, Zheng T, Sang S, Lv L. NC A&T University Abstract Methylglyoxal (MGO) and glyoxal (GO) are not only endogenous metabolites, but also exist in exogenous resources, such as food, beverages, urban atmosphere, and cigarette smoke. They […]

Bioavailability and Hypolipidemic Effects of Peanut Skin Polyphenols

September 03, 2014

Bioavailability and Hypolipidemic Effects of Peanut Skin Polyphenols J Med Food. 2014 Sep 3, Bansode RR1, Randolph P, Ahmedna M, Williams LL, Yu J.  Center for Excellence in Post Harvest Technologies, North Carolina Agricultural and Technical State University , North Carolina Research Campus, Kannapolis, North Carolina, USA . Abstract Abstract Peanut skin is a rich source of polyphenols, such as proanthocyanidins. Peanut skin proanthocyanidins mainly consist of a subgroup […]

Ginger Compound [6]-Shogaol and Its Cysteine-conjugated Metabolite (M2) Activate Nrf2 in Colon Epithelial Cells in Vitro and in Vivo.

August 22, 2014

Ginger Compound [6]-Shogaol and Its Cysteine-conjugated Metabolite (M2) Activate Nrf2 in Colon Epithelial Cells in Vitro and in Vivo. Chem Res Toxicol. 2014 Aug 22, Chen H, Fu J, Chen H, Hu Y, Soroka DN, Prigge J, Schmidt EE, Yan F, Major MB, Chen XL, Sang S. Abstract In this study, we identified Nrf2 as a molecular target of [6]-shogaol (6S), a bioactive compound isolated from ginger, in […]

A&T SIGNS AGREEMENT TO COMMERCIALIZE HYPOALLERGENIC PEANUT

June 08, 2014

North Carolina A&T Hypoallergenic peanuts, peanut butter, and other peanut products are a step closer to grocery stores with the signing of an exclusive licensing agreement for the patented process that reduces allergens in peanuts by 98 percent. North Carolina Agricultural and Technical State University signed the agreement with Xemerge, a Toronto-based firm that commercializes […]

Effect of microfluidisation on antioxidant properties of corn bran

June 01, 2014

Effect of microfluidisation on antioxidant properties of corn bran. Food Chemistry. June 1, 2014 Wang T, Zhu Y, Sun X, Raddatz J, Zhou Z, Chen G. Center for Excellence in Post-Harvest Technologies, North Carolina A&T State University, NC Research Campus; School of Food Science & Technology, Dalian Polytechnic University, Dalian, China; Center for Translational & Biomedical Research, The University of North […]

Production and characterization of biochars from agricultural by-products for use in soil quality enhancement

April 24, 2014

Production and characterization of biochars from agricultural by-products for use in soil quality enhancement Apr 24, 2014 D. Rehraha, M.R. Reddyb, J.M. Novakc, R.R. Bansodeb, K.A. Schimmelb, J. Yub, D.W. Wattsc, M. Ahmednaa,    Department of Health Sciences, College of Arts and Sciences, Qatar University, Doha, Qatar b Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and […]

Essential Structural Requirements and Additive Effects for Flavonoids to Scavenge Methylglyoxal

April 01, 2014

Essential Structural Requirements and Additive Effects for Flavonoids to Scavenge Methylglyoxal. Journal of Agricultural and Food Chemistry. April 1, 2014. [Epub ahead of print] Shao X, Chen H, Zhu Y, Sedighi R, Ho CT, Sang S. Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University , North Carolina Research Campus. Abstract Reactive dicarbonyl species, such as […]

Microfluidization of Brans and Uses Thereof

February 28, 2014

Microfluidization of Brans and Uses Thereof FPO 28 Feb 2014, Chen, Guibing (Concord, NC, US) ,Raddatz, Julia (Cornelius, NC, US), Wang, Tao (Kannapolis, NC, US) Abstract The present application generally relates to the development of palatable fiber-enriched foodstuffs, including but not limited to soups, salad dressings, dips, sauces, baked goods and beverages, through modifying various dietary fiber ingredients using […]

Induction of Lung Cancer Cell Apoptosis through a p53 Pathway by [6]-Shogaol and Its Cysteine-Conjugated Metabolite M2

February 12, 2014

Induction of Lung Cancer Cell Apoptosis through a p53 Pathway by [6]-Shogaol and Its Cysteine-Conjugated Metabolite M2. Journal of Agricultural Food Chemistry. January 30, 2014. Epub ahead of print. Warin RF, Chen H, Soroka DN, Zhu Y, Sang S. Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus Abstract Dietary chemoprevention of […]