metabolites

Go Fish! Zebrafish Advance Cancer Research

March 08, 2015

In the fight against cancer, zebrafish may seem like an unlikely weapon. For TinChung Leung, PhD, with the North Carolina Central University Nutrition Research Program at the NC Research Campus (NCRC) in Kannapolis, zebrafish have the potential to deliver the answers to some of the most fundamental questions about cancer. Namely how tumors grow and […]

NCA&T Research Technician Honored for Work on Wheat and Cancer Prevention

February 02, 2015

NCA&T Research Technician Nicholas Stone is a finalist in the Undergraduate Student Research Symposium sponsored by the Agricultural and Food Chemistry Division (AGFD) of the American Chemical Society (ACS). The AGFD symposium is open to all undergraduates conducting research in agricultural food chemistry. Stone, a senior biology major at Davidson College, is one of six […]

Cysteine-Conjugated Metabolites of Ginger Components, Shogaols, Induce Apoptosis through Oxidative Stress-Mediated p53 Pathway in Human Colon Cancer Cells

May 21, 2014

Cysteine-Conjugated Metabolites of Ginger Components, Shogaols, Induce Apoptosis through Oxidative Stress-Mediated p53 Pathway in Human Colon Cancer Cells. Journal of Agricultural Food Chemistry. May 21, 2014; Epub 2014 May 12. Fu J1, Chen H, Soroka DN, Warin RF, Sang S. 1Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus , 500 Laureate […]

Metabolomics approach to assessing plasma 13- and 9-hydroxy-octadecadienoic acid

April 23, 2014

Am J Physiol Regul Integr Comp Physiol. 2014 Apr 23. [Epub ahead of print] Metabolomics approach to assessing plasma 13- and 9-hydroxy-octadecadienoic acid and linoleic acid metabolite responses to 75-km cycling. Nieman DC, Shanely RA, Luo B, Meaney MP, Dew DA, Pappan KL. Appalachian State University Human Performance Laboratory, NC Research Campus. Abstract Bioactive oxidized linoleic acid metabolites (OXLAMs) include 13- […]

Arabidopsis: An Ideal Plant

April 15, 2014

From biofuels to better crops, Xu “Sirius” Li, PhD, an assistant professor and plant metabolic pathway engineer with the NC State University Plants for Human Health Institute, applies his research with the model plant system Arabidopsis and secondary metabolites, also known as phytonutrients, to meet real-world challenges.  Read More.

Arabidopsis: An Ideal Platform for Understanding Secondary Metabolites

March 02, 2014

Xu “Sirius” Li, PhD, an assistant professor and plant metabolic pathway engineer with the NC State University Plants for Human Health Institute (PHHI), uses the model plant system Arabidopsis to understand how plants produce secondary metabolites and support human health. In collaboration with other scientists at PHHI and at the NC Research Campus, he is […]

What are Polyphenols?

September 13, 2013

Polyphenols are a class of bioactive compounds commonly found in fruits and vegetables and used by them to protect themselves from pests and environmental stress.  A wealth of research suggests that when humans consume these compounds a variety of health benefits may be experienced including lowering of blood pressure and blood glucose, reducing inflammation and fighting off […]

Grains for Better Health and Disease Prevention

June 13, 2013

  Shengmin Sang, PhD, with the NC A&T Center for Excellence in Post-Harvest Technologies, is researching metabolites and dietary markers of grains like wheat and rye that can help increase their use as a preventative for diabetes and lung and colon cancer. Sang and  NC A&T’s Guibing Chen, PhD, are experimenting with a process called microfluidization […]