metabolism

You, Your Metabolism, and Science: How Research Studies Can Fight the Obesity Epidemic

July 03, 2018

The one-of-a-kind Human Whole-Room Calorimeter at the UNC Chapel Hill Nutrition Research Institute can be used for a wide variety of research studies – but they need YOU to participate. Read on to learn about how this technology works, how experts at the Appalachian State University Human Performance Laboratory are studying metabolism, how these studies […]

Cardiovascular Mechanisms of Action of Anthocyanins May Be Associated with the Impact of Microbial Metabolites on Heme Oxygenase-1 in Vascular Smooth Muscle Cells

June 21, 2018

Warner EF1, Rodriguez-Ramiro I2, O’Connell MA3, Kay CD4. Cardiovascular Mechanisms of Action of Anthocyanins May Be Associated with the Impact of Microbial Metabolites on Heme Oxygenase-1 in Vascular Smooth Muscle Cells. Molecules. 2018 Apr 13;23(4). pii: E898. doi: 0.3390/molecules23040898. Author information 1 Department of Nutrition and Preventative Medicine, Norwich Medical School, Bob Champion Research and Education Building, University of […]

Is Your Metabolism Really the Master of Your Weight?

January 05, 2017

Read the original article, “Is Your Metabolism Really the Master of Your Weight? Expert Tips to Get Your System Running Smoothly” by Parade’s Catherine Winters All day your metabolism churns away, converting food to fuel throughout your body so everything—from your circulatory system to your hormones and heart to your bones and brain—can do their jobs, says […]

Altered Transport and Metabolism of Phenolic Compounds in Obesity and Diabetes: Implications for Functional Food Development and Assessment

December 08, 2016

Benjamin W Redan, Kimberly K Buhman, Janet A Novotny, and Mario G Ferruzzi (2016). Altered Transport and Metabolism of Phenolic Compounds in Obesity and Diabetes: Implications for Functional Food Development and Assessment. Advances in Nutrition vol. 7: 1090-1104. Author Affiliations 3. Interdepartmental Nutrition Program, Department of Nutrition Science, and 4. Department of Food Science, Purdue […]

Cancer, Obesity and Diet- New Research from UNC NRI

March 30, 2016

Watch Dr. Hursting talk about his latest findings on WJZY/Fox News Charlotte. Stephen Hursting, PhD, MPH, with the UNC Lineberger Comprehensive Cancer Center, UNC Gillings School of Global Public Health and the UNC Nutrition Research Institute at the NC Research Campus in Kannapolis, leads a team of researchers who explore the link between cancer, obesity and […]

Metabolism of dictamnine in liver microsomes from mouse, rat, dog, monkey, and human

November 18, 2015

Metabolism of dictamnine in liver microsomes from mouse, rat, dog, monkey, and human, Journal of Pharmaceutical and Biomedical Analysis. November 18, 2015. Pei Wang (A,B), Yunli Zhao (A), Yingdong Zhu (B), Jianbo Sun (C), Aaron Yerke (B), Shengmin Sang (B), Zhiguo Yu (A). Author Affiliations A School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China […]

An assessment of molecular pathways of obesity susceptible to nutrient, toxicant and genetically induced epigenetic perturbation

October 15, 2015

An assessment of molecular pathways of obesity susceptible to nutrient, toxicant and genetically induced epigenetic perturbation, JNB,  15 Oct 2015, Jing Xue, Folami Y. Ideraabdullah, UNC Chapel Hill Abstract In recent years, the etiology of human disease has greatly improved with the inclusion of epigenetic mechanisms, in particular as a common link between environment and disease. However, for […]

Novel Resveratrol-based Aspirin Prodrugs: Synthesis, Metabolism, and Anticancer Activity

July 23, 2015

Novel Resveratrol-based Aspirin Prodrugs: Synthesis, Metabolism, and Anticancer Activity, J Med Chem. 2015 J Zhu Y, Fu J, Shurlknight K, Soroka D, Hu Y, Chen XL, Sang S. Abstract Regular aspirin use has been convincingly shown to reduce the risk of colorectal cancer. However, long-term use of aspirin leads to gastrotoxicity. Herein, we designed and synthesized […]

Cytokine expression and secretion by skeletal muscle cells: regulatory mechanisms and exercise effects

February 24, 2015

Cytokine expression and secretion by skeletal muscle cells: regulatory mechanisms and exercise effects, Queensland University, Feb 2015, Jonathan M. Peake1, Paul Della Gatta2, Katsuhiko Suzuki3, David C. Nieman4 Affiliations: 1 School of Biomedical Sciences and Institute of Health and Biomedical Sciences, Queensland University of Technology, Brisbane, Australia 2 Centre for Physical Activity and Nutrition, School of Exercise and […]

Interactions Between Nuclear receptor SHP and FOXA1 Maintain Oscillatory Homocysteine Homeostasis in Mice

February 18, 2015

Interactions Between Nuclear receptor SHP and FOXA1 Maintain Oscillatory Homocysteine Homeostasis in Mice, Gastroenterology. 2015 Feb 18, Tsuchiya H1, Costa KA2, Lee S3, Renga B4, Jaeschke H5, Yang Z6, Orena SJ2, Goedken MJ7, Zhang Y5, Bo K8, Lebofsky M5, Rudraiah S3, Smalling R1, Guo G8, Fiorucci S4, Zeisel SH2, Wang L9. Department of Medicine, University of Utah […]

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique

September 10, 2014

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique JoVE Clinical and Translational Medicine, Sept 10, 2014, R. Andrew Shanely1,2, Kevin A. Zwetsloot2, N. Travis Triplett2, Mary Pat Meaney1,2, Gerard E. Farris3, David C. Nieman Human Performance Laboratory, North Carolina Research Campus, Appalacian State University, 2College of Health Sciences, Appalachian State University, 3Department of Emergency Medicine, […]

Turbocharge Your Food- Excercising Ups Nutrient Absorption from Berries, Tea

July 15, 2014

As published in the Dole Nutrition Institute’s July 2014 newsletter. “Gut permeability,” “leaky colon,” “hot gut”– none of these terms conjure up conditions you’d think to put on your wish list.  The colon carries digested food away from the stomach and towards the exit, so “leaking” would be the very last thing you’d want your […]

Effects of a freeze-dried juice blend powder on exercise-induced inflammation, oxidative stress, and immune function in cyclists

March 06, 2014

Effects of a freeze-dried juice blend powder on exercise-induced inflammation, oxidative stress, and immune function in cyclists.  Applied Physiology, Nutrition and Metabolism. March 2014. Knab AM, Nieman DC, Gillitt ND, Shanely RA, Cialdella-Kam L, Henson D, Sha W, Meaney MP. Human Performance Laboratory, Appalachian State University, North Carolina Research Campus; Dole Nutrition Research Laboratory, NC Research Campus; UNC Charlotte Bioinformatics Services Division, […]

Ginger Shogaols: Promising Preventation for Lung and Colon Cancer

June 20, 2013

Shengmin Sang, PhD, associate professor and lead scientist in functional food for NC A&T State University’s Center for Excellence in Post Harvest Technologies (CEPHT) at the North Carolina Research Campus in Kannapolis, has published four peer-reviewed articles this year that further the understanding of the chemopreventive potential of ginger. Sang’s most recent findings concentrate on […]

Perinatal epigenetic determinants of cognitive and metabolic disorders

December 08, 2012

Perinatal epigenetic determinants of cognitive and metabolic disorders Aging and Disease.Aging and Disease. December 2012. Lupo, DS, Tint D, Niculescu MD. UNC Chaple Hill Nutrition Research Institute. Abstract Multiple cues from the environment of our indirect and immediate ancestors, which often persist throughout the prenatal period and adulthood, are shaping our phenotypes through either direct, […]

How to Get Your Metabolism Moving

December 30, 2011

by Health 12/30/11 Does your metabolism grind to a halt after 35? Can certain foods rev it up? Answers ahead — and they’re good. By Paige Greenfield Here’s something to feel good about: your body is a calorie-burning machine. You’ll even torch a few while reading this article. The point is, every single thing you do — from breathing […]