A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential. Clinical Cancer Research: An Official Journal of the American Association of Cancer Research. March 25, 2014. Qiu Y, Cai G, Zhou B, Li D, Zhao A, Xie G, Li H, Cai S, Xie D, Huang C, Ge W, Zhou Z, Xu LX, Jia W, Zheng S, Yen Y, Jia W. Center for Translational Medicine, Shanghai Jiao Tong University Affiliated Sixth […]
Scientists at the North Carolina Research Campus (NCRC) in Kannapolis have discovered in a human trial enhanced polyphenolic absorption via the colon into the blood stream. The same human study also found that polyphenolic supplementation in combination with exercise creates a long-lasting spike in polyphenolic metabolism. The study provides clear evidence of an alternate route […]
Humans harvest grains primarily for the nutritional value of the endosperm, the placenta-like tissue inside the seeds of most flowering plants that nourishes the embryo. Tzung-Fu Hsieh, PhD, with the NC State University Plants for Human Health Institute (PHHI), is leading research to unravel the biological complexities surrounding endosperm development. In collaboration with Xu “Sirius” Li, PhD, a plant metabolic pathway […]
The human genetic code is 99.9 percent identical. What makes people individuals, genetically speaking, equates to .1 percent of their individual genetic make-up and accounts for thousands of differentiations at the molecular level. Deciphering those differentiations or polymorphisms and their involvement in the development of disease is the work of scientists like Karen Corbin, PhD, RD, […]
Diet-gene interactions underlie metabolic individuality and influence brain development: implications for clinical practice derived from studies on choline metabolism.
Diet-gene interactions underlie metabolic individuality and influence brain development: implications for clinical practice derived from studies on choline metabolism. Annals of Nutrition Metabolism, May 2012. Zeisel SH. UNC Chapel Hill Nutrition Research Institute. Abstract One of the underlying mechanisms for metabolic individuality is genetic variation. Single nucleotide polymorphisms (SNPs) in genes of metabolic pathways can create […]
Metabolic profiling reveals disorder of amino acid metabolism in various brain regions from a rat model of chronic unpredictable mild stress
Ni, N., Su, M., Lin, J., Wang, X., Qiu, Y., Zhao, A., Chen, T., Jia, W.*Metabolic profiling reveals disorder of amino acid metabolism in various brain regions from a rat model of chronic unpredictable mild stress, FEBS Letters, Vol. 582 (17), 2627-2636, 2008. Abstract Chronic stress is closely linked to clinical depression, which could be […]