Metabolic Profiling

Metabolic profiling reveals the protective effect of diammonium glycyrrhizinate on acute hepatic injury induced by carbon tetrachloride

June 12, 2011

Metabolic profiling reveals the protective effect of diammonium glycyrrhizinate on acute hepatic injury induced by carbon tetrachloride Xiaoyan Wang, Jingchao Lin, Tianlu Chen, Mingmei Zhou, Mingming Su, Wei Jia Abstract Diammonium glycyrrhizinate (DG), a constitutent of Glycyrrhiza uralensis, has a protective effect on hepatic injury, hepatisis and cirrhosis. To date, the mechanism has been poorly understood, especially at the metabolic level. A […]

Mass Spectrometry-based Metabolic Profiling of Rat Urine Associated with General Toxicity Induced by Multiglycoside of Tripterygium Wilfordii Hook

March 19, 2008

Chen, M.,Ni, Y., Duan, H., Qiu, Y., Guo, C., Jiao, Y., Shi, H., Su, M., Jia, W.*Mass Spectrometry-based Metabolic Profiling of Rat Urine Associated with General Toxicity Induced by Multiglycoside of Tripterygium Wilfordii Hook. F.,Chemical Research in Toxicology, 21: 288-294, 2008. Abstract We propose here a combined gas chromatography/mass spectrometry (GC/MS) and liquid chromatography/mass spectrometry […]