liver dysfunction

Aberrant estrogen regulation of PEMT results in choline deficiency-associated liver dysfunction.

March 18, 2010

Resseguie, M.,da Costa, K-A, Galanko, J., Davis, I.J., Zeisel, S.H. (2010)Aberrant estrogen regulation of PEMT results in choline deficiency-associated liver dysfunction. Journal of Biological Chemistry.286(2): 1649-58. PMCID: PMC3020773. Abstract When dietary choline is restricted, most men and postmenopausal women develop multiorgan dysfunction marked by hepatic steatosis (choline deficiency syndrome (CDS)). However, a significant subset of […]