Inflammation

Metabolic Effects of Berries with Structurally Diverse Anthocyanins

February 23, 2017

John Overall, Sierra A. Bonney, Mickey Wilson, Arnold Beermann III, Mary H. Grace, Debora Esposito, Mary Ann Lila, and Slavko Komarnytsky (2017). Metabolic Effects of Berries with Structurally Diverse Anthocyanins. International Journal of Molecular Sciences 18(2), 422. Author Affiliations 1. Plants for Human Health Institute, North Carolina State University, North Carolina Research Campus, 600 Laureate […]

Bioactive Brief: Targeting Hepatic PPAR Gamma Signaling To Treat Alcoholic Liver Disease

May 05, 2016

A certain signaling pathway in the liver has been identified as a factor in the progression of alcoholic liver disease, report scientists from the University of North Carolina at Greensboro’s Center for Translational Biomedical Research at the NC Research Campus. Peroxisome proliferator-activated receptor gamma (PPARγ) signaling governs several processes in the body tissues such as […]

Altered Maturation Status and Possible Immune Exhaustion of CD8 T Lymphocytes in the Peripheral Blood of Patients Presenting With Acute Coronary Syndromes

December 10, 2015

Altered Maturation Status and Possible Immune Exhaustion of CD8 T Lymphocytes in the Peripheral Blood of Patients Presenting With Acute Coronary Syndromes, Arteriosclerosis, Thrombosis and Vascular Biology, December 10, 2015. David A. Zidar, Joseph C. Mudd, Steven Juchnowski, Joao P. Lopes, Sara Sparks,Samantha S. Park, Masakazu Ishikawa, Robyn Osborne, Jeffrey B. Washam, Cliburn Chan, Nicholas T. Funderburg, Adeyinka Owoyele, Mohamad A. Alaiti, Myttle Mayuga, Carl Orringer, Marco […]

Healthy Living Cooking Series Returns: Learn about foods that may prevent or treat common diseases

September 10, 2015

  KANNAPOLIS, N.C. – Two additional offerings of the Plants for Human Health, Health Living Cooking Series will be offered this fall, following the success of two full classes offered earlier this summer. Aubrey Mast, Extension associate, at N.C. State University’s Plants for Human Health Institute at the N.C. Research Campus in Kannapolis, will, again, […]

The elite athlete paradox: how running a marathon can make you ill

August 27, 2015

Although exercise is good for you, when that exercise is extremely intense – for example during the training and completion of a hard race – the immune system is supressed, leaving an open window for infection The elite athlete paradox states that, although exercise is good for health, extreme exercise can suppress the immune system, […]

No Positive Influence of Ingesting Chia Seed Oil on Human Running Performance

May 15, 2015

No Positive Influence of Ingesting Chia Seed Oil on Human Running Performance, 15 May 2015,  Nutrients , David C. Nieman 1,*, Nicholas D. Gillitt 2, Mary Pat Meaney 1 and Dustin A. Dew Human Performance Laboratory, Appalachian State University, North Carolina Research Campus, Kannapolis, NC 28081, USA; E-Mails: meaneymp@appstate.edu (M.P.M.); dustindew@gmail.com (D.A.D.) Dole Nutrition Research Laboratory, […]

Alaskan seaweeds lower inflammation in RAW 264.7 macrophages and decrease lipid accumulation in 3T3-L1 adipocytes

April 14, 2015

Alaskan seaweeds lower inflammation in RAW 264.7 macrophages and decrease lipid accumulation in 3T3-L1 adipocytes, 14 Apr 2015, Journal of Functional Foods. Joshua Kellogg, Debora Esposito, Mary H. Grace, Slavko Komarnytsky, Mary Ann Lila NC State University Abstract Chronic inflammation is characterized by macrophage accumulation in adipose tissue, which subsequently up-regulates pro-inflammatory cytokines and promotes the dysregulation of lipid metabolism, […]

Influence of Pistachios on Performance and Exercise-Induced Inflammation, Oxidative Stress, Immune Dysfunction, and Metabolite Shifts in Cyclists: A Randomized, Crossover Trial.

November 19, 2014

Influence of Pistachios on Performance and Exercise-Induced Inflammation, Oxidative Stress, Immune Dysfunction, and Metabolite Shifts in Cyclists: A Randomized, Crossover Trial. PLoS One. 2014 Nov 19, Nieman DC1, Scherr J2, Luo B3, Meaney MP1, Dréau D4, Sha W5, Dew DA1, Henson DA6, Pappan KL7. Appalachian State University, Human Performance Lab, North Carolina Research Campus, Kannapolis, NC, United States of America. 2Department of Prevention and […]

Soyasaponins Can Blunt Inflammation by Inhibiting the Reactive Oxygen Species-Mediated Activation of PI3K/Akt/NF-kB Pathway.

September 01, 2014

Soyasaponins Can Blunt Inflammation by Inhibiting the Reactive Oxygen Species-Mediated Activation of PI3K/Akt/NF-kB Pathway. PLoS One. 2014 Sep 1, Zha L1, Chen J2, Sun S2, Mao L2, Chu X2, Deng H2, Cai J3, Li X4, Liu Z5, Cao W6. 1Department of Nutrition and Food Hygiene, School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou, China; Nutrition Research Institute at Kannapolis, Department of Nutrition, Gillings School […]

P2EP’s Year-Round Scientific and Educational Impact

August 07, 2014

The 40 Plant Pathways Elucidation Project (P2EP) interns at the NC Research Campus (NCRC) presented the results of their summer of research in an August 5 symposium sponsored by the NC Biotechnology Center. Through P2EP, a STEM-based workforce development program, the interns studied pathways in blueberries, strawberries, oats and broccoli that produce health-enhancing bioactive compounds. […]

Turbocharge Your Food- Excercising Ups Nutrient Absorption from Berries, Tea

July 15, 2014

As published in the Dole Nutrition Institute’s July 2014 newsletter. “Gut permeability,” “leaky colon,” “hot gut”– none of these terms conjure up conditions you’d think to put on your wish list.  The colon carries digested food away from the stomach and towards the exit, so “leaking” would be the very last thing you’d want your […]

Effect of egg ingestion on trimethylamine-N-oxide production in humans: a randomized, controlled, dose-response study

June 26, 2014

Effect of egg ingestion on trimethylamine-N-oxide production in humans: a randomized, controlled, dose-response study. Jun 26, 2014 The American Journal of Clinical Nutrition. August 2014. Carolyn A Miller, Karen D Corbin, Kerry-Ann da Costa, Shucha Zhang, Xueqing Zhao, Joseph A Galanko, Tondra Blevins, Brian J Bennett, Annalouise O’Connor, and Steven H Zeisel. The Nutrition Research Institute, University of North Carolina at Chapel Hill, […]

Role of Salivary and Candidal Proteins in Denture Stomatitis; an exploratory proteomic analysis

June 11, 2014

Role of Salivary and Candidal Proteins in Denture Stomatitis; an exploratory proteomic analysis. Molecular Biosystem. June 11, 2014.  Warren C Byrd,  Sarah Schwartz Baxter,  James Carlson,  Silvana Barros,  Steven Offenbacher and Sompop Bencharit. 1Department of Prosthodontics, School of Dentistry, Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA; 2David H. Murdock […]

Metabolomics approach to assessing plasma 13- and 9-hydroxy-octadecadienoic acid

April 23, 2014

Am J Physiol Regul Integr Comp Physiol. 2014 Apr 23. [Epub ahead of print] Metabolomics approach to assessing plasma 13- and 9-hydroxy-octadecadienoic acid and linoleic acid metabolite responses to 75-km cycling. Nieman DC, Shanely RA, Luo B, Meaney MP, Dew DA, Pappan KL. Appalachian State University Human Performance Laboratory, NC Research Campus. Abstract Bioactive oxidized linoleic acid metabolites (OXLAMs) include 13- […]

A commercialized dietary supplement alleviates joint pain in community adults: a double-blind, placebo-controlled community trial.

November 25, 2013

A commercialized dietary supplement alleviates joint pain in community adults: a double-blind, placebo-controlled community trial. Nutrition Journal. November 25, 2013. David C Nieman, R Andrew Shanely, Beibei Luo, Dustin Dew, Mary Pat Meaney, and Wei Sha. Appalachian State University, Human Performance Lab, North Carolina Research Campus; Key Laboratory of Exercise and Health Sciences of Ministry […]

Runners suffer more inflammation and muscle damage than cyclists

October 23, 2013

Medical Press New scientific findings give endurance runners a reason to consider varying their training regime to include other sports. The study, Immune and Inflammation Responses to a 3-day Period of Intensified Running Versus Cycling, was conducted by the Appalachian State University (ASU) Human Performance Laboratory at the North Carolina Research Campus in Kannapolis. After […]