Ginger

Triad professor receives patent for cancer-fighting compounds

September 26, 2017

Read the original article by Jessica Seaman from the Triad Business Journal. A professor at N.C. A&T State University has received a patent for compounds that have the potential to prevent and treat cancer, the university announced. Shengmin Sang received the patent for combining aspirin and ginger derivatives. By combing the compounds with anti-cancer properties, they […]

Shengmin Sang of NCA&T Wins Innovation for Impact Grand Prize

March 30, 2017

By Barry Teater, NCBiotech Writer. Research to prevent colon cancer by pairing the classic wonder drug aspirin with an active ingredient in ginger has earned a Greensboro scientist a statewide honor that carries an $11,000 reward. Shengmin Sang, Ph.D., associate professor with the North Carolina Agricultural and Technical State University in Greensboro,was awarded the inaugural Innovation […]

NCA&T’s Shengmin Sang Reaping Research Rewards

March 30, 2017

By Mindy Hamlin, NCBiotech Writer. Read the original article on the NC Biotech Center website. It has been a good run lately for Shengmin Sang, Ph.D. Sang, associate professor and lead scientist in the Center for Excellence in Post-Harvest Technologies ​at North Carolina Agricultural and Technical State University labs in Kannapolis, was awarded the inaugural […]

Shengmin Sang Leading NC A&T to Front of Fight on Cancer

August 03, 2016

Read the original article on Diverse Issues in Higher Education. A prolific scholar and 2015 winner of the Research Article of the Year award from the Journal of Agricultural and Food Chemistry, Dr. Shengmin Sang is helping to position historically Black North Carolina A&T State University (N.C. A&T) into a center of cutting-edge cancer research. […]

Bioactive Brief: Ginger-Derived Compounds Activate Cytoprotective Molecules

May 26, 2016

In an innovative study from NC Research Campus partners at the NC A&T Center for Excellence in Post-Harvest Technologies (the Sang lab) and the NC Central Nutrition Research Program (the Leung lab), scientists discovered four novel, cytoprotective compounds derived from dry ginger that act as the “most potent Nrf2 activators” in a zebrafish embryo model. The […]

Six More Dietary Ingredients Picked for Analytical Evaluation

March 03, 2016

By Richard A. Lovett, JD, PhD, Contributing Writer Read the original article in Nutraceuticals World An advisory panel has selected aloe vera, vitamin B12, protein, ginger, vitamins K1 and K2 and free amino acids as priority ingredients for review. In a continuing endeavor to help the dietary supplements industry agree on and evaluate analytical methods […]

Resveratrol-based prodrug may be a safe aspirin substitute

December 11, 2015

New research from the North Carolina A&T State University at the North Carolina Research Campus in Kannapolis, NC confirmed that a patented, resveratrol-based prodrug reduces aspirin side effects and enhances the anti-cancer properties of both aspirin and resveratrol. Aspirin is recognized as the over-the-counter-drug for pain and fever relief and the prevention of cardiovascular disease, […]

Ginger, Other Plant Compounds Found to Delay Diabetic Complications

October 15, 2015

Read the story in Nutraceuticals World. Ginger compounds and some flavonoids are effective at stopping physiological processes that lead to diabetic complications. Scientific evidence is building that plant compounds may be a safe and effective alternative to approved pharmaceutical treatments for type 2 diabetes because they provide a natural means to prevent diabetic complications without side […]

Plant Compounds Delay Diabetic Complications, Offer New Treatment Options

September 22, 2015

Research from Shengmin Sang, PhD, at the NC Research Campus in Kannapolis, NC, is proving that ginger compounds and some flavonoids are effective at stopping physiological processes that lead to diabetic complications.   Scientific evidence is building that plant compounds may be a safe and effective alternative to approved pharmaceutical treatments for type 2 diabetes […]

Bioactive Ginger Constituents Alleviate Protein Glycation by Trapping Methylglyoxal

August 13, 2015

Bioactive Ginger Constituents Alleviate Protein Glycation by Trapping Methylglyoxal, Chem Res Toxicol. 2015 Aug 13, Zhu Y1, Zhao Y1, Wang P1, Ahmedna M, Sang S1. 1†Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus, 500 Laureate Way, Kannapolis, North Carolina 28081, United States. Abstract Considerable evidence suggests […]

Go Fish! Zebrafish Advance Cancer Research

March 08, 2015

In the fight against cancer, zebrafish may seem like an unlikely weapon. For TinChung Leung, PhD, with the North Carolina Central University Nutrition Research Program at the NC Research Campus (NCRC) in Kannapolis, zebrafish have the potential to deliver the answers to some of the most fundamental questions about cancer. Namely how tumors grow and […]

Plasma Cholesterol-Lowering Activity of Gingerol- and Shogaol-Enriched Extract Is Mediated by Increasing Sterol Excretion

October 16, 2014

Plasma Cholesterol-Lowering Activity of Gingerol- and Shogaol-Enriched Extract Is Mediated by Increasing Sterol Excretion. Journal of Agricultural and Food Chemistry. October 7, 2014. Lin Lei †, Yuwei Liu †, Xiaobo Wang †, Rui Jiao ‡,Ka Ying Ma †, Yuk Man Li †, Lijun Wang †, Sun Wa Man †, Shengmin Sang §, Yu Huang #, and Zhen-Yu Chen *† Author Affiliations † Food and Nutritional Sciences Programme, School of Life Sciences, The Chinese University of Hong Kong, […]

Ginger Compound [6]-Shogaol and Its Cysteine-conjugated Metabolite (M2) Activate Nrf2 in Colon Epithelial Cells in Vitro and in Vivo.

August 22, 2014

Ginger Compound [6]-Shogaol and Its Cysteine-conjugated Metabolite (M2) Activate Nrf2 in Colon Epithelial Cells in Vitro and in Vivo. Chem Res Toxicol. 2014 Aug 22, Chen H, Fu J, Chen H, Hu Y, Soroka DN, Prigge J, Schmidt EE, Yan F, Major MB, Chen XL, Sang S. Abstract In this study, we identified Nrf2 as a molecular target of [6]-shogaol (6S), a bioactive compound isolated from ginger, in […]

Cysteine-Conjugated Metabolites of Ginger Components, Shogaols, Induce Apoptosis through Oxidative Stress-Mediated p53 Pathway in Human Colon Cancer Cells

May 21, 2014

Cysteine-Conjugated Metabolites of Ginger Components, Shogaols, Induce Apoptosis through Oxidative Stress-Mediated p53 Pathway in Human Colon Cancer Cells. Journal of Agricultural Food Chemistry. May 21, 2014; Epub 2014 May 12. Fu J1, Chen H, Soroka DN, Warin RF, Sang S. 1Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus , 500 Laureate […]

A Model Fish

January 15, 2014

Scientists with North Carolina Central University Nutrition Research Program and NCA&T’s Center for Excellence in Post-Harvest Technologies teamed up to study the bioactive compounds in ginger. They did it using a rather model fish called zebrafish. NC Central scientist TinChung Leung, PhD, uses the model fish for research into natural compounds that can help prevent […]

NCCU and NCA&T Cancer Research on UNC-TV

December 18, 2013

UNC TV Researchers can’t test experimental cures for diseases and possible drug therapies on humans so they use the zebrafish for initial testing. That’s because the journey from egg to embryo is the same in zebrafish and humans. The image on the computer screen in the North Carolina Central University lab at the North Carolina […]

Ginger Shogaols: Promising Prevention for Lung and Colon Cancer

August 13, 2013

Shengmin Sang, PhD, associate professor and leadscientist in functional food for NC A&T State University’s Center for Excellence in Post Harvest Technologies, published four peer-reviewed articles this year that further the understanding of the chemopreventive potential of ginger. Sang’s most recent findings concentrate on shogaol metabolites and lung and colon cancer prevention. Shogaols are the dehydrated […]

Ginger Shogaols: Promising Preventation for Lung and Colon Cancer

June 20, 2013

Shengmin Sang, PhD, associate professor and lead scientist in functional food for NC A&T State University’s Center for Excellence in Post Harvest Technologies (CEPHT) at the North Carolina Research Campus in Kannapolis, has published four peer-reviewed articles this year that further the understanding of the chemopreventive potential of ginger. Sang’s most recent findings concentrate on […]

Ginger Shogaols: Promising Preventation for Lung and Colon Cancer

June 15, 2013

North Carolina Research Campus Shengmin Sang, PhD, associate professor and lead scientist in functional food for NC A&T State University’s Center for Excellence in Post Harvest Technologies (CEPHT) at the North Carolina Research Campus in Kannapolis, has published four peer-reviewed articles this year that further the understanding of the chemopreventive potential of ginger. Sang’s most […]

[10]-Gingerdiols as the Major Metabolites of [10]-Gingerol in Zebrafish Embryos and in Humans and Their Hematopoietic Effects in Zebrafish Embryos.

May 23, 2013

[10]-Gingerdiols as the Major Metabolites of [10]-Gingerol in Zebrafish Embryos and in Humans and Their Hematopoietic Effects in Zebrafish Embryos. Journal of Agricultural and Food Chemistry.  Epub May 23, 2013. Chen H, Soroka DN, Haider J, Ferri-Lagneau KF, Leung T (NC Central University Nutrition Research Program), Sang S. Center for Excellence in Post-Harvest Technologies, North […]