Geoffrey Ginsburg

Differential evolution of peripheral cytokine levels in symptomatic and asymptomatic responses to experimental influenza virus challenge

October 28, 2015

Differential evolution of peripheral cytokine levels in symptomatic and asymptomatic responses to experimental influenza virus challenge, Clin Exp Immunol. 2015 Oct 28, McClain MT1,2,3, Henao R1,4, Williams J2, Nicholson B2, Veldman T1, Hudson L1, Tsalik EL1,2,3, Lambkin-Williams R5, Gilbert A5, Mann A5, Ginsburg GS1,Woods CW1,2,3. 1Center for Applied Genomics and Precision Medicine, , Duke University, Durham, NC. […]

Lessons learned from pre-implementation activities to integrate a web-based personalized health risk assessment program in diverse primary care settings

August 28, 2015

Lessons learned from pre-implementation activities to integrate a web-based personalized health risk assessment program in diverse primary care settings, Implementation Science 2015, Lori A Orlando, R Ryanne Wu, Nina Sperber, Geoffrey S Ginsburg and Corrine Voils. 1Department of Medicine, Duke University, Durham, NC 27705, USA 2Center for Applied Genomics and Precision Medicine, Duke University, Durham, NC 27705, […]

Making Personalized Health Care Even More Personalized: Insights From Activities of the IOM Genomics Roundtable

July 13, 2015

Making Personalized Health Care Even More Personalized: Insights From Activities of the IOM Genomics Roundtable Personalized Health Care Even More Personalized: Insights From Activities of the IOM Genomics Roundtable, Ann Fam Med. 2015 Jul;13, David SP1, Johnson SG2, Berger AC3, Feero WG4, Terry SF5, Green LA6, Phillips RL Jr7, Ginsburg GS8. 1Department of Medicine, Stanford University School […]

What was old is new again: using the host response to diagnose infectious disease

July 04, 2015

What was old is new again: using the host response to diagnose infectious disease, Expert Rev Mol Diagn. 2015 Jul 4, Ko ER1, Yang WE, McClain MT, Woods CW, Ginsburg GS, Tsalik EL. 1Department of Medicine Center for Applied Genomics & Precision Medicine, Duke University, Durham, NC 27708, USA. Abstract A century of advances in infectious disease […]

Gene Expression Signatures and the Spectrum of Coronary Artery Disease.

June 19, 2015

Gene Expression Signatures and the Spectrum of Coronary Artery Disease. J Cardiovasc Transl Res. 2015 Jun 19,Friede KA1, Ginsburg GS, Voora D. Department of Medicine, Duke University, Durham, NC, USA. Abstract Over the past 10-15 years, developments in gene expression profiling have opened new arenas for the discovery of important factors in the pathogenesis of numerous disease […]

Perceptions of personalized medicine in an academic health system: Educational findings

May 13, 2015

Perceptions of personalized medicine in an academic health system: Educational findings, 13 May 2015,  Journal of Contemporary Medical Education, Allison Vorderstrasse, Sara Huston Katsanis, Mollie A Minear, Nancy Yang, Tejinder Rakhra-Burris, Jason W Reeves, Robert Cook-Deegan, Geoffrey S Ginsburg, Leigh Ann Simmons. Abstract Objective: Prior reports demonstrate that personalized medicine implementation in clinical care is […]

Does Type 2 Diabetes Genetic Testing and Counseling Reduce Modifiable Risk Factors? A Randomized Controlled Trial of Veterans.

April 16, 2015

Does Type 2 Diabetes Genetic Testing and Counseling Reduce Modifiable Risk Factors? A Randomized Controlled Trial of Veterans. 2015 Apr 16, J Gen Intern Med., Voils CI1, Coffman CJ, Grubber JM, Edelman D, Sadeghpour A, Maciejewski ML, Bolton J, Cho A, Ginsburg GS, Yancy WS Jr. 1Center for Health Services Research in Primary Care, Durham Veterans Affairs Medical […]

SLCO1B1 genetic variants, long-term low-density lipoprotein cholesterol levels and clinical events in patients following cardiac catheterization

April 16, 2015

SLCO1B1 genetic variants, long-term low-density lipoprotein cholesterol levels and clinical events in patients following cardiac catheterization, 2015 Apr 16, Pharmacogenomics. Li JH1, Suchindran S, Shah SH, Kraus WE, Ginsburg GS, Voora D. 1Duke Center for Applied Genomics & Precision Medicine, Duke University, 101 Science Drive, Durham, NC 27705, USA. Abstract AIM: SLCO1B1 variants are associated with intermediate outcomes […]

Patient Beliefs and Behaviors About Genomic Risk for Type 2 Diabetes: Implications for Prevention

April 06, 2015

Patient Beliefs and Behaviors About Genomic Risk for Type 2 Diabetes: Implications for Prevention, 2015 Apr 6, J Health Commun, Gallagher P1, King HA, Haga SB, Orlando LA, Joy SV, Trujillo GM, Scott WM, Bembe M, Creighton DL, Cho AH, Ginsburg GS, Vorderstrasse A. Altisource, Inc. , Winston-Salem , North Carolina , USA. Abstract Type 2 diabetes is […]

Pilot study of pharmacist-assisted delivery of pharmacogenetic testing in a primary care setting.

September 15, 2014

Pilot study of pharmacist-assisted delivery of pharmacogenetic testing in a primary care setting. Pharmacogenomics. 2014 Sep;15, Haga SB1, Allen LaPointe NM, Cho A, Reed SD, Mills R, Moaddeb J, Ginsburg GS. 1Duke University Center for Applied Genomics & Precision Medicine, 304 Research Drive, Box 90141 Durham, NC 27708, USA. Abstract AIM: To describe the rationale and design […]

The current epidemiology and clinical decisions surrounding acute respiratory infections

September 05, 2014

The current epidemiology and clinical decisions surrounding acute respiratory infections Trends Mol Med. 2014 Sep 5, Zaas AK1, Garner BH2, Tsalik EL3, Burke T2, Woods CW3, Ginsburg GS2. Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, NC, USA; Department of Medicine, Duke University School of Medicine, Durham, NC, USA. Electronic address: aimee.zaas@duke.edu. 2Center for Applied Genomics and Precision […]

Use of a Patient-Entered Family Health History Tool with Decision Support in Primary Care: Impact of Identification of Increased Risk Patients on Genetic Counseling Attendance.

August 15, 2014

Use of a Patient-Entered Family Health History Tool with Decision Support in Primary Care: Impact of Identification of Increased Risk Patients on Genetic Counseling Attendance. J Genet Couns. 2014 Aug 15, Buchanan AH1, Christianson CA, Himmel T, Powell KP, Agbaje A, Ginsburg GS, Henrich VC, Orlando LA. Duke Cancer Institute, Duke University, DUMC 2715 2424 Erwin Rd., Suite 602, Durham, NC, 27705, USA, adam.buchanan@duke.edu. Abstract […]

Comparing reference-based RNA-Seq mapping methods for non-human primate data

July 11, 2014

Comparing reference-based RNA-Seq mapping methods for non-human primate data.Jul 11,2014  BMC Genomics. Ashlee M Benjamin1; Marshall Nichols1; Thomas W Burke1; Geoffrey S Ginsburg1; Joseph E Lucas2; 1Center for Applied Genomics, Department of Medicine, Duke University, Durham, North Carolina, USA 2Department of Electrical and Computer Engineering, Duke University, Durham, North Carolina, USA. Author details: 1Center for Applied Genomics, Department of Medicine, Duke University,Durham, North Carolina, USA. 2Department […]

Multiplex detection of disease biomarkers using SERS molecular sentinel-on-chip.

May 24, 2014

Multiplex detection of disease biomarkers using SERS molecular sentinel-on-chip. Anal Bioanal Chem. 2014 May, Ngo HT1, Wang HN, Burke T, Ginsburg GS, Vo-Dinh T. 1Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA. Abstract Developing techniques for multiplex detection of disease biomarkers is important for clinical diagnosis. In this work, we have demonstrated for the first […]

Duke, DHMRI Discover Blood-based Test for Aspirin Therapy

July 15, 2013

This month Duke Medicine physicians and researchers published the paper Aspirin Exposure Reveals Novel Genes Associated with Platelet Function and Cardiovascular Events in the Journal of the American College of Cardiology. They reported that the significance of the findings is that they have “solved some of the mysteries related to the use of this century-old […]

DHMRI Advances Personalized Medicine in North Carolina

July 03, 2012

DHMRI Advances Personalized Medicine in North Carolina Personalized medicine is transforming healthcare through the combination of diagnostic tests and therapeutic treatments. The result is a shift to a healthcare model that takes into account individual differences and the influence of genetics and environment. The advantage is more effective treatments, an enhanced ability to predict risk […]