Duke University

Genetics of CD33 in Alzheimer’s Disease and Acute Myeloid Leukemia.

March 11, 2015

Genetics of CD33 in Alzheimer’s Disease and Acute Myeloid Leukemia. Hum Mol Genet. 2015 Mar 11, Malik M, Chiles J 3rd, Xi HS, Medway C, Simpson J, Potluri S, Howard D, Liang Y, Paumi CM, Mukherjee S, Crane P, Younkin S, Fardo DW, Estus S. Abstract The CD33 single nucleotide polymorphism (SNP) rs3865444 has been associated with the risk of Alzheimer’s disease (AD). Rs3865444 is in […]

Implementation of Management Strategies for Diabetes and Hypertension: From Local to Global Health in Cardiovascular Diseases

March 11, 2015

Implementation of Management Strategies for Diabetes and Hypertension: From Local to Global Health in Cardiovascular Diseases, Glob Heart. 2015 Mar, Bloomfield GS1, Wang TY1, Boulware LE1, Califf RM1, Hernandez AF1, Velazquez EJ1, Peterson ED1, Li JS2. Duke University Medical Center and Duke Clinical Research Institute, Durham, NC. 2Duke University Medical Center and Duke Clinical Research Institute, Durham, […]

Prognostic Implications of Low Level Cardiac Troponin Elevation Using High‐Sensitivity Cardiac Troponin T

March 03, 2015

Prognostic Implications of Low Level Cardiac Troponin Elevation Using High‐Sensitivity Cardiac Troponin T, Clin Cardiol. 2015 Mar 3, Grinstein J1, Bonaca MP, Jarolim P, Conrad MJ, Bohula-May E, Deenadayalu N, Braunwald E, Giugliano RP, Newby LK, Sabatine MS, Morrow DA. Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts. Abstract BACKGROUND: High-sensitivity cardiac troponin T (hsTnT) is […]

Effectiveness of practices for improving the diagnostic accuracy of Non ST Elevation Myocardial Infarction in the Emergency Department: A Laboratory Medicine Best Practices™ systematic review.

February 07, 2015

Effectiveness of practices for improving the diagnostic accuracy of Non ST Elevation Myocardial Infarction in the Emergency Department: A Laboratory Medicine Best Practices™ systematic review. Clin Biochem. 2015 Feb 7, Layfield C1, Rose J2, Alford A2, Snyder SR3, Apple FS4, Chowdhury FM5, Kontos MC6, Newby LK7, Storrow AB8, Tanasijevic M9, Leibach E5, Shaw C5, Liebow EB10, Christenson […]

Duke to Expand Footprint in Kannapolis

January 27, 2015

Contact: Clyde Higgs Vice President of Business Development 704-273-1204 chiggs@ncresearchcampus.net Emily Ford Communications Specialist MURDOCK Study 704-642-2208 emily.ford@duke.edu   Kannapolis, N.C.  — Officials from the North Carolina Research Campus (NCRC) formally announced today that Duke University is expanding its presence at their site.  Duke originally opened an office there in 2008 to manage the MURDOCK […]

Methods and initial findings from the Durham Diabetes Coalition: Integrating geospatial health technology and community interventions to reduce death and disability

January 14, 2015

Methods and initial findings from the Durham Diabetes Coalition: Integrating geospatial health technology and community interventions to reduce death and disability 14 January 2015, Journal of Clinical & Translational Endocrinology. Susan E. Spratta, , ,Bryan C. Batcha,Lisa P. Davisb, c,Ashley A. Dunhamb, c,Michele Easterlingd,Mark N. Feinglosa,Bradi B. Grangere,Gayle Harrisd,Michelle J. Lynf,Pamela J. axsong,Bimal R. Shahc,Benjamin Straussg,Tainayah Thomasd,Robert […]

MURDOCK Study Contributor Warns Against Children & Energy Drinks

December 16, 2014

Our kids are downing energy drinks at an alarming rate Published in the Durham Herald Sun, November 22, 2014. Read the original article. Written by Diane Uzarski, doctoral student at the Duke University School of Nursing and key contributor to the MURDOCK Study’s research on Alzheimer’s. As North Carolina begins its beloved college basketball season, […]

Duke University’s MURDOCK Study adds project leader for strategy

December 11, 2014

KANNAPOLIS, N.C.—Dec. 11, 2014—Douglas Wixted has joined Duke University’s MURDOCK Study team as a project leader. Wixted will manage a number of strategic initiatives for the MURDOCK Study, including a focus on informatics, efficient and scalable infrastructure, and maximizing data quality and value. He worked with the MURDOCK Study from 2011 to 2013 and re-joined […]

Simultaneous Consideration of Multiple Candidate Protein Biomarkers for Long-Term Risk for Cardiovascular Events

November 24, 2014

Simultaneous Consideration of Multiple Candidate Protein Biomarkers for Long-Term Risk for Cardiovascular Events, Circ Cardiovasc Genet. 2014 Nov 24, Halim SA1, Neely ML2, Pieper KS2, Shah SH3, Kraus WE4, Hauser ER5, Califf RM6, Granger CB1, Newby LK7. 1Division of Cardiology & Duke Clinical Research Institute, Duke University Medical Center, Durham, NC. 2Duke Clinical Research Institute, Duke University […]

Venous Thromboembolism and Cardiovascular Risk: Results from the NAVIGATOR Trial

November 20, 2014

Venous Thromboembolism and Cardiovascular Risk: Results from the NAVIGATOR Trial   The American Journal of Medicine, 20 November 2014,  Marcelo Katz, MDa, b, Robert M. Califf, MDc, Jie-Lena Sun, MSd, John J.V. McMurray, MDe, Laine Thomas, PhDd, Renato D. Lopes, MD, PhD, MHSd, Brazilian Clinical Research Institute, Sao Paulo, Brazil b Hospital Israelita Albert Einstein, Sao Paulo, Brazil c Duke Translational Medicine Institute, Duke […]

Translation of acute coronary syndrome therapies: From evidence to routine clinical practice

November 12, 2014

Translation of acute coronary syndrome therapies: From evidence to routine clinical practice  12 November 2014, American Heart Journal, Martin Putera, MDa, Robin Roark, MD, MBAb, Renato D. Lopes, MD, PhDb, Krishna Udayakumar, MD, MBAa, b, c, Eric D. Peterson, MD, MPHb, Robert M. Califf, MDb, c, Bimal R. Shah, MD, MBAb, d Translation of acute coronary syndrome therapies: From evidence to routine clinical practice […]

Comparative Assessment of Short-term Adverse Events in Acute Heart Failure With Cystatin C and Other Estimates of Renal Function : Results From the ASCEND-HF Trial

November 11, 2014

Comparative Assessment of Short-term Adverse Events in Acute Heart Failure With Cystatin C and Other Estimates of Renal Function  : Results From the ASCEND-HF Trial, Science Direct  11 November 2014   W.H. Wilson Tang, MD∗, , , Matthias Dupont, MD†, Adrian F. Hernandez, MD‡, Adriaan A. Voors, MD§, Amy P. Hsu, MS∗, G. Michael Felker, MD‡, Javed Butler, MD‖, Marco Metra, MD¶, Stefan D.  nker, MD, […]

The Correlation of Patient Reported versus Observed Medication Adherence in Type 2 Diabetes (T2DM)

November 08, 2014

The Correlation of Patient Reported versus Observed Medication Adherence in Type 2 Diabetes (T2DM) American Heart Association 2014, Katherine Kelly1; Maria Grau-Sepulveda2; Leoncio Flavio Rojas3; Bryan C Batch4; Melodie Staton5; Anne Wolfley2; Vicki Hatfield6; Monica Murphy7; Ellen Jones8; Bradi Granger 2Duke Clinical Rsch Institute, Duke Univ, Durham, NC 3Duke Transational Medicine Institute, Duke Univ, Durham, NC 4Medicine – Endocrinology and Metabolism, Duke Univ Sch of Medicine, Durham, […]

Acute Decompensated Heart Failure Patients Admitted to Critical Care Units: Insights from ASCEND-HF

November 04, 2014

Acute Decompensated Heart Failure Patients Admitted to Critical Care Units: Insights from ASCEND-HF, International Journal of Cardiology, Nov 3, 2014, Sean van Diepen, Divisions of Critical Care and Cardiology, University of Alberta, Edmonton, Alberta, Canada, Mohua Podder,  Vigour Center, Edmonton, Alberta, Canada, Adrian F. Hernandez, Clinical Research Institute, Duke University Medical Center, Durham, NC, USA, Cynthia M. Westerhout,  Vigour Center Alberta, Canada, Paul W. […]

Check It, Change It: A Community-Based, Multifaceted Intervention to Improve Blood Pressure Control.

October 28, 2014

Check It, Change It: A Community-Based, Multifaceted Intervention to Improve Blood Pressure Control. Circ Cardiovasc Qual Outcomes. 2014 Oct 28, Thomas KL1, Shah BR2, Elliot-Bynum S2, Thomas KD2, Damon K2, Allen LaPointe NM2, Calhoun S2, Thomas L2, Breathett K2, Mathews R2, Anderson M2,Califf RM2, Peterson ED2. 1From the Department of Medicine, Duke University, Durham, NC (K.L.T., B.R.S., […]

Long-term Clinical and Angiographic Outcomes in Patients with Diabetes Undergoing Coronary Artery Bypass Graft Surgery: Results from the PREVENT IV Trial

October 23, 2014

Long-term Clinical and Angiographic Outcomes in Patients with Diabetes Undergoing Coronary Artery Bypass Graft Surgery: Results from the PREVENT IV Trial, Published Online: October 23, 2014 ,  American Heart Journal<style>.requiresJS{display:none}.dartAd{display:block !important}</style> Masaya Koshizaka, Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, Renato D. Lopes, Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, Eric M. Reyes, Rose-Hulman Institute […]

Pilot study of pharmacist-assisted delivery of pharmacogenetic testing in a primary care setting.

September 15, 2014

Pilot study of pharmacist-assisted delivery of pharmacogenetic testing in a primary care setting. Pharmacogenomics. 2014 Sep;15, Haga SB1, Allen LaPointe NM, Cho A, Reed SD, Mills R, Moaddeb J, Ginsburg GS. 1Duke University Center for Applied Genomics & Precision Medicine, 304 Research Drive, Box 90141 Durham, NC 27708, USA. Abstract AIM: To describe the rationale and design […]

The current epidemiology and clinical decisions surrounding acute respiratory infections

September 05, 2014

The current epidemiology and clinical decisions surrounding acute respiratory infections Trends Mol Med. 2014 Sep 5, Zaas AK1, Garner BH2, Tsalik EL3, Burke T2, Woods CW3, Ginsburg GS2. Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, NC, USA; Department of Medicine, Duke University School of Medicine, Durham, NC, USA. Electronic address: aimee.zaas@duke.edu. 2Center for Applied Genomics and Precision […]

Clinical characteristics and outcomes with rivaroxaban vs. warfarin in patients with non-valvular atrial fibrillation but underlying native mitral and aortic valve disease participating in the ROCKET AF trial.

August 22, 2014

Clinical characteristics and outcomes with rivaroxaban vs. warfarin in patients with non-valvular atrial fibrillation but underlying native mitral and aortic valve disease participating in the ROCKET AF trial. Eur Heart J. 2014 Aug 22, Breithardt G1, Baumgartner H2, Berkowitz SD3, Hellkamp AS4, Piccini JP4, Stevens SR4, Lokhnygina Y4, Patel MR4, Halperin JL5, Singer DE6, Hankey GJ7,Hacke W8, Becker RC4, Nessel CC9, Mahaffey KW10, Fox KA11, Califf RM12; for the ROCKET AF Steering Committee & […]

Use of a Patient-Entered Family Health History Tool with Decision Support in Primary Care: Impact of Identification of Increased Risk Patients on Genetic Counseling Attendance.

August 15, 2014

Use of a Patient-Entered Family Health History Tool with Decision Support in Primary Care: Impact of Identification of Increased Risk Patients on Genetic Counseling Attendance. J Genet Couns. 2014 Aug 15, Buchanan AH1, Christianson CA, Himmel T, Powell KP, Agbaje A, Ginsburg GS, Henrich VC, Orlando LA. Duke Cancer Institute, Duke University, DUMC 2715 2424 Erwin Rd., Suite 602, Durham, NC, 27705, USA, adam.buchanan@duke.edu. Abstract […]