Duke University

MURDOCK-NCRC Seed Funding Voucher Awardees

August 02, 2016

The MURDOCK Study has awarded six $10,000 vouchers as part of the MURDOCK-NCRC Seed Funding Voucher Program to investigators from North Carolina Research Campus partners. Duke University and the MURDOCK Study are pleased to announce the following voucher recipients: Saroja Voruganti, PhD, UNC Nutrition Research Institute (UNC NRI) “A pilot study to identify polymorphisms associated […]

Duke increases its presence on the NCRC; Clinical research is a growth industry in Kannapolis

November 17, 2015

By Mary Price See the original article in Business Today Ashley Dunham, PhD, director of operations for Translational Population Research, part of the Duke Translational Medicine Institute (DTMI), was one of the four original employees hired by the Duke University School of Medicine to work the MURDOCK Study Community Registry and Biorepository—the research that most […]

Does This Patient With Chest Pain Have Acute Coronary Syndrome?

November 10, 2015

Does This Patient With Chest Pain Have Acute Coronary Syndrome? The Rational Clinical Examination Systematic Review, The Journal of the American Medical Association. Alexander C. Fanaroff, MD1,2; Jennifer A. Rymer, MD, MBA1,2; Sarah A. Goldstein, MD2; David L. Simel, MD, MHS3; L. Kristin Newby, MD, MHS1,2,4 Author Affiliations 1Division of Cardiology, Duke University, Durham, North Carolina 2Department of Medicine, Duke University, Durham, North Carolina 3Durham Veterans […]

Frequency, clinical and angiographic characteristics, and outcomes of high-risk Non–ST-segment elevation acute coronary syndromes patients with left circumflex culprit lesions

November 04, 2015

Frequency, clinical and angiographic characteristics, and outcomes of high-risk Non–ST-segment elevation acute coronary syndromes patients with left circumflex culprit lesions, International Journal of Cardiology, Sharif A. Halim, Robert M. Clare, L. Kristin Newby, Yuliya Lokhnygina, Marc J. Schweiger, Arnoud W. Hof, Judith S. Hochman, Stefan K. James, Harvey D. White, Petr Widimsky, Amadeo Betriu, Christoph Bode, Robert P. Giugliano, Robert A. Harrington, Uwe Zeymer. Author Affiliations Division of Cardiology […]

Procedural and Clinical Outcomes after Use of the Glycoprotein IIb/IIIa inhibitor Abciximab for Saphenous Vein Graft Interventions

October 30, 2015

Procedural and Clinical Outcomes after Use of the Glycoprotein IIb/IIIa inhibitor Abciximab for Saphenous Vein Graft Interventions, 30 oct, 2015, Cardiovascular Revascularization Medicine, Ralf E. Harskamp, Niels Hoedemaker, L. Kristin Newby, Pier Woudstra, Maik J. Grundeken, Marcel A. Beijk, Jan J. Piek, Jan G. Tijssen, Rajendra H. Mehta, Robbert J. de Winter Academic Medical Center – University of Amsterdam, Amsterdam, The Netherlands,VU University Medical Center, […]

Differential evolution of peripheral cytokine levels in symptomatic and asymptomatic responses to experimental influenza virus challenge

October 28, 2015

Differential evolution of peripheral cytokine levels in symptomatic and asymptomatic responses to experimental influenza virus challenge, Clin Exp Immunol. 2015 Oct 28, McClain MT1,2,3, Henao R1,4, Williams J2, Nicholson B2, Veldman T1, Hudson L1, Tsalik EL1,2,3, Lambkin-Williams R5, Gilbert A5, Mann A5, Ginsburg GS1,Woods CW1,2,3. 1Center for Applied Genomics and Precision Medicine, , Duke University, Durham, NC. […]

CAP [mdash] advancing the evaluation of preclinical Alzheimer disease treatments

September 29, 2015

CAP [mdash] advancing the evaluation of preclinical Alzheimer disease treatments, Nat Rev Neurol. 2015 Sep 29, Reiman EM1, Langbaum JB1, Tariot PN1, Lopera F2, Bateman RJ3, Morris JC3, Sperling RA4, Aisen PS5, Roses AD6, Welsh-Bohmer KA6, Carrillo MC7,Weninger S8. 1Banner Alzheimer‘s Institute, 901 E. Willetta Street, Phoenix, AZ 85006, USA. 2Grupo de Neurosciencias, Universidad de Antioquia, Calle […]

MURDOCK Study Hosts First Mass Enrollment Just for NCRC

September 10, 2015

September 10, 2015 Dear Campus Colleague, Greetings from Duke University and the MURDOCK Study! For the first time, anyone who works at the North Carolina Research Campus can join the MURDOCK Study, regardless of where you live. We invite you to consider enrolling in this unique, community-based longitudinal health study during a special all-day event […]

Lessons learned from pre-implementation activities to integrate a web-based personalized health risk assessment program in diverse primary care settings

August 28, 2015

Lessons learned from pre-implementation activities to integrate a web-based personalized health risk assessment program in diverse primary care settings, Implementation Science 2015, Lori A Orlando, R Ryanne Wu, Nina Sperber, Geoffrey S Ginsburg and Corrine Voils. 1Department of Medicine, Duke University, Durham, NC 27705, USA 2Center for Applied Genomics and Precision Medicine, Duke University, Durham, NC 27705, […]

A Guide for a Cardiovascular Genomics Biorepository: the CATHGEN Experience

August 14, 2015

A Guide for a Cardiovascular Genomics Biorepository: the CATHGEN Experience, J Cardiovasc Transl Res. 2015 Aug 14, Kraus WE1, Granger CB, Sketch MH Jr, Donahue MP, Ginsburg GS, Hauser ER, Haynes C, Newby LK, Hurdle M, Dowdy ZE, Shah SH. Author information 1Division of Cardiology, Department of Medicine, School of Medicine, Duke University, Durham, NC, 27710, USA, […]

Making Personalized Health Care Even More Personalized: Insights From Activities of the IOM Genomics Roundtable

July 13, 2015

Making Personalized Health Care Even More Personalized: Insights From Activities of the IOM Genomics Roundtable Personalized Health Care Even More Personalized: Insights From Activities of the IOM Genomics Roundtable, Ann Fam Med. 2015 Jul;13, David SP1, Johnson SG2, Berger AC3, Feero WG4, Terry SF5, Green LA6, Phillips RL Jr7, Ginsburg GS8. 1Department of Medicine, Stanford University School […]

What was old is new again: using the host response to diagnose infectious disease

July 04, 2015

What was old is new again: using the host response to diagnose infectious disease, Expert Rev Mol Diagn. 2015 Jul 4, Ko ER1, Yang WE, McClain MT, Woods CW, Ginsburg GS, Tsalik EL. 1Department of Medicine Center for Applied Genomics & Precision Medicine, Duke University, Durham, NC 27708, USA. Abstract A century of advances in infectious disease […]

Duke’s MURDOCK Study offers $100,000 in seed funding to NCRC scientists

July 02, 2015

  KANNAPOLIS, N.C.—July 2, 2015—Duke University’s MURDOCK Study will invest up to $100,000 in the coming year to fund scientific discoveries at the North Carolina Research Campus (NCRC) in Kannapolis. The MURDOCK Study-NCRC Seed Funding Voucher Program will provide up to 10 vouchers worth $10,000 each to qualifying NCRC investigators from any institution on the […]

Gene Expression Signatures and the Spectrum of Coronary Artery Disease.

June 19, 2015

Gene Expression Signatures and the Spectrum of Coronary Artery Disease. J Cardiovasc Transl Res. 2015 Jun 19,Friede KA1, Ginsburg GS, Voora D. Department of Medicine, Duke University, Durham, NC, USA. Abstract Over the past 10-15 years, developments in gene expression profiling have opened new arenas for the discovery of important factors in the pathogenesis of numerous disease […]

Sex-Stratified Trends in Enrollment, Patient Characteristics, Treatment, and Outcomes Among Non–ST-Segment Elevation Acute Coronary Syndrome Patients

June 08, 2015

Sex-Stratified Trends in Enrollment, Patient Characteristics, Treatment, and Outcomes Among Non–ST-Segment Elevation Acute Coronary Syndrome Patients , June 8, 2015, American Heart Association, Inc, Kristian Kragholm, MD*, Sharif A. Halim, MD, MHS*, Qinghong Yang, MSc, Phillip J. Schulte, MSc, PhD, Judith S. Hochman, MD, Chiara Melloni, MD, Kenneth W. Mahaffey, MD, David J. Moliterno, MD, Robert A. Harrington, MD, Harvey D. White, DSc, Paul W. Armstrong, MD, E. Magnus Ohman, […]

Perceptions of personalized medicine in an academic health system: Educational findings

May 13, 2015

Perceptions of personalized medicine in an academic health system: Educational findings, 13 May 2015,  Journal of Contemporary Medical Education, Allison Vorderstrasse, Sara Huston Katsanis, Mollie A Minear, Nancy Yang, Tejinder Rakhra-Burris, Jason W Reeves, Robert Cook-Deegan, Geoffrey S Ginsburg, Leigh Ann Simmons. Abstract Objective: Prior reports demonstrate that personalized medicine implementation in clinical care is […]

Does Type 2 Diabetes Genetic Testing and Counseling Reduce Modifiable Risk Factors? A Randomized Controlled Trial of Veterans.

April 16, 2015

Does Type 2 Diabetes Genetic Testing and Counseling Reduce Modifiable Risk Factors? A Randomized Controlled Trial of Veterans. 2015 Apr 16, J Gen Intern Med., Voils CI1, Coffman CJ, Grubber JM, Edelman D, Sadeghpour A, Maciejewski ML, Bolton J, Cho A, Ginsburg GS, Yancy WS Jr. 1Center for Health Services Research in Primary Care, Durham Veterans Affairs Medical […]

SLCO1B1 genetic variants, long-term low-density lipoprotein cholesterol levels and clinical events in patients following cardiac catheterization

April 16, 2015

SLCO1B1 genetic variants, long-term low-density lipoprotein cholesterol levels and clinical events in patients following cardiac catheterization, 2015 Apr 16, Pharmacogenomics. Li JH1, Suchindran S, Shah SH, Kraus WE, Ginsburg GS, Voora D. 1Duke Center for Applied Genomics & Precision Medicine, Duke University, 101 Science Drive, Durham, NC 27705, USA. Abstract AIM: SLCO1B1 variants are associated with intermediate outcomes […]

Patient Beliefs and Behaviors About Genomic Risk for Type 2 Diabetes: Implications for Prevention

April 06, 2015

Patient Beliefs and Behaviors About Genomic Risk for Type 2 Diabetes: Implications for Prevention, 2015 Apr 6, J Health Commun, Gallagher P1, King HA, Haga SB, Orlando LA, Joy SV, Trujillo GM, Scott WM, Bembe M, Creighton DL, Cho AH, Ginsburg GS, Vorderstrasse A. Altisource, Inc. , Winston-Salem , North Carolina , USA. Abstract Type 2 diabetes is […]

A novel Alzheimer disease locus located near the gene encoding tau protein

March 17, 2015

A novel Alzheimer disease locus located near the gene encoding tau protein, Mol Psychiatry. 2015 Mar 17, Jun G1, Ibrahim-Verbaas CA2, Vronskaya M3, Lambert JC4, Chung J5, Naj AC6, Kunkle BW7, Wang LS6, Bis JC8, Bellenguez C4, Harold D9, Lunetta KL10,Destefano AL10, Grenier-Boley B4, Sims R3, Beecham GW11, Smith AV12, Chouraki V13, Hamilton-Nelson KL7, Ikram MA14, Fievet […]