Colon Cancer

NCA&T’s Shengmin Sang Reaping Research Rewards

March 30, 2017

By Mindy Hamlin, NCBiotech Writer. Read the original article on the NC Biotech Center website. It has been a good run lately for Shengmin Sang, Ph.D. Sang, associate professor and lead scientist in the Center for Excellence in Post-Harvest Technologies ​at North Carolina Agricultural and Technical State University labs in Kannapolis, was awarded the inaugural […]

N.C. A&T and Industry to Bring Novel Aspirin Derivatives to the Marketplace

March 21, 2017

Read the original article from North Carolina A&T State University. Greensboro, N.C. (March 14, 2017) – Patients who require the benefits of aspirin without the accompanying stomach irritation are a step closer to comfort and cures with the signing of an exclusive licensing agreement. Dr. Shengmin Sang, a food scientist with North Carolina Agricultural and […]

Gastroprotective [6]-Gingerol Aspirinate as a Novel Chemopreventive Prodrug of Aspirin for Colon Cancer

January 19, 2017

Yingdong Zhu, Fang Wang, Yantao Zhao, Pei Wang & Shengmin Sang. Gastroprotective [6]-Gingerol Aspirinate as a Novel Chemopreventive Prodrug of Aspirin for Colon Cancer. Scientific Reports 7 (2017). Author Affiliations Laboratory for Functional Foods and Human Health, Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus, 500 […]

Chemopreventative Effect of Phytochemimcals against Colon Cancer

December 17, 2015

Chemopreventative Effect of Phytochemimcals against Colon Cancer, Medicinal and Aromatic Plants, December 2015. Williams LL, Khatiwada J and Davis S. Center for Excellence in Post-Harvest Technologies, North Carolina A&T State University, North Carolina Research Campus, Kannapolis, NC. Editorial Currently, the incidence of colorectal cancer (CRC) has been declining, even though it remains a major public […]

Resveratrol-based prodrug may be a safe aspirin substitute

December 11, 2015

New research from the North Carolina A&T State University at the North Carolina Research Campus in Kannapolis, NC confirmed that a patented, resveratrol-based prodrug reduces aspirin side effects and enhances the anti-cancer properties of both aspirin and resveratrol. Aspirin is recognized as the over-the-counter-drug for pain and fever relief and the prevention of cardiovascular disease, […]

Synergistic Effects of Fiber and Phytochemicals in Wheat Bran on Colon Cancer

April 07, 2015

Synergistic Effects of Fiber and Phytochemicals in Wheat Bran on Colon Cancer, Apr 2015, The FASEB Journal, Jennifer McBride1, Yingdong Zhu1, Pei Wang1 and Shengmin Sang1 1Center for Excellence in Post-Harvest Technologies North Carolina Agricultural and Technical State University Kannapolis NC United States Abstract Colorectal cancer (CRC) is a leading cause of cancer related deaths in the United States. Epidemiological […]

Oxyphytosterols as Active Ingredients in Wheat Bran Suppress Human Colon Cancer Cell Growth: Identification, Chemical Synthesis and Biological Evaluation

February 06, 2015

Oxyphytosterols as Active Ingredients in Wheat Bran Suppress Human Colon Cancer Cell Growth: Identification, Chemical Synthesis and Biological Evaluation, J Agric Food Chem. 2015 Feb 6, Zhu Y, Soroka D, Sang S. NC A&T University Abstract Consumption of whole grains has been reported to be associated with a lower risk of several lifestyle-related diseases such as colorectal […]

Cysteine-Conjugated Metabolites of Ginger Components, Shogaols, Induce Apoptosis through Oxidative Stress-Mediated p53 Pathway in Human Colon Cancer Cells

May 21, 2014

Cysteine-Conjugated Metabolites of Ginger Components, Shogaols, Induce Apoptosis through Oxidative Stress-Mediated p53 Pathway in Human Colon Cancer Cells. Journal of Agricultural Food Chemistry. May 21, 2014; Epub 2014 May 12. Fu J1, Chen H, Soroka DN, Warin RF, Sang S. 1Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus , 500 Laureate […]

Ginger Shogaols: Promising Preventation for Lung and Colon Cancer

June 15, 2013

North Carolina Research Campus Shengmin Sang, PhD, associate professor and lead scientist in functional food for NC A&T State University’s Center for Excellence in Post Harvest Technologies (CEPHT) at the North Carolina Research Campus in Kannapolis, has published four peer-reviewed articles this year that further the understanding of the chemopreventive potential of ginger. Sang’s most […]

Grains for Better Health and Disease Prevention

June 13, 2013

  Shengmin Sang, PhD, with the NC A&T Center for Excellence in Post-Harvest Technologies, is researching metabolites and dietary markers of grains like wheat and rye that can help increase their use as a preventative for diabetes and lung and colon cancer. Sang and  NC A&T’s Guibing Chen, PhD, are experimenting with a process called microfluidization […]

Structure Elucidation and Chemical Profile of Sphingolipids in Wheat Bran and Their Cytotoxic Effects against Human Colon Cancer Cells.

January 30, 2013

Structure Elucidation and Chemical Profile of Sphingolipids in Wheat Bran and Their Cytotoxic Effects against Human Colon Cancer Cells. Journal of Agricultural and Food Chemistry. January 30, 2013. Zhu Y, Soroka DN, Sang S. Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus. Abstract Sphingolipids are known to have […]

Synthesis and inhibitory activities against colon cancer cell growth and proteasome of alkylresorcinols

September 10, 2012

Synthesis and inhibitory activities against colon cancer cell growth and proteasome of alkylresorcinols. Journal of Agricultural and Food Chemistry. September 2012. Zhu Y, Soroka DN, Sang S. Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus. Abstract We have identified alkylresorcinols (ARs) as the major active components […]

5-Alk(en)ylresorcinols as the major active components in wheat bran inhibit human colon cancer cell growth

July 12, 2011

5-Alk(en)ylresorcinols as the major active components in wheat bran inhibit human colon cancer cell growth Yingdong Zhu, Dawn R. Conklin, Huadong Chen, Liyan Wang, Shengmin Sang Abstract We and others have found that wheat bran oil is the active constituent in wheat bran for colon cancer prevention. However, the active components in wheat bran oil are still unknown. Using […]