Brian Bennett

Nutrition and the science of disease prevention: a systems approach to support metabolic health

September 13, 2015

Nutrition and the science of disease prevention: a systems approach to support metabolic health, Ann N Y Acad Sci. 2015 Sep, Bennett BJ1, Hall KD2, Hu FB3, McCartney AL4, Roberto C5. 1Departments of Genetics and Nutrition, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina. 2Integrative Physiology Section, National Institute of Diabetes […]

The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice

June 03, 2015

The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice, 2015 Jun 3, Stem Cell Reports. Zhou X1, Crow AL2, Hartiala J2, Spindler TJ1, Ghazalpour A3, Barsky LW1, Bennett BB4, Parks BW3, Eskin E5, Jain R6, Epstein JA6, Lusis AJ3, Adams GB7,Allayee H8. Author information 1Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at […]

Identification of Aortic Arch-Specific Quantitative Trait Loci for Atherosclerosis by an Intercross of DBA/2J and 129S6 Apolipoprotein E-Deficient Mice.

February 17, 2015

Identification of Aortic Arch-Specific Quantitative Trait Loci for Atherosclerosis by an Intercross of DBA/2J and 129S6 Apolipoprotein E-Deficient Mice. PLoS One. 2015 Feb 17, Kayashima Y1, Makhanova NA1, Matsuki K1, Tomita H1, Bennett BJ2, Maeda N1. Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America. […]

High-Resolution Genetic Mapping in the Diversity Outbred Mouse Population Identifies Apobec1 as a Candidate Gene for Atherosclerosis

October 23, 2014

High-Resolution Genetic Mapping in the Diversity Outbred Mouse Population Identifies Apobec1 as a Candidate Gene for Atherosclerosis G3 (Bethesda). 2014 Oct 23, Smallwood TL1, Gatti DM2, Quizon P3, Weinstock GM4, Jung KC1, Zhao L1, Hua K1, Pomp D1, Bennett BJ5. University of North Carolina at Chapel Hill; 2The Jackson Laboratory; 3University of North Carolina Nutrition Research Institute; […]

Responsiveness of cardiometabolic-related microbiota to diet is influenced by host genetics.

August 27, 2014

Responsiveness of cardiometabolic-related microbiota to diet is influenced by host genetics. Mamm Genome. 2014 Aug 27, O’Connor A1, Quizon PM, Albright JE, Lin FT, Bennett BJ. UNC Chapel Hill Nutrition Research Institute, 500 Laureate Way, Kannapolis, NC, 28081, USA. Abstract Intestinal microbial community structure is driven by host genetics in addition to environmental factors such as diet. In comparison with environmental influences, the effect of host genetics on intestinal microbiota, […]

Genetic network identifies novel pathways contributing to atherosclerosis susceptibility in the innominate artery

August 12, 2014

Genetic network identifies novel pathways contributing to atherosclerosis susceptibility in the innominate artery BMC Med Genomics. 2014 Aug 12, Albright J, Quizon PM, Lusis AJ, Bennett BJ. Department of Genetics, Nutrition Research Institute, University of North, Carolina, Chapel Hill, 500 Laureate Way, Suite 2303, Kannapolis, NC 28081, USA Abstract BACKGROUND: Atherosclerosis, the underlying cause of cardiovascular disease, results from both genetic and environmental factors. METHODS: […]

A Small Amount of Dietary Carbohydrate Can Promote the HFD-Induced Insulin Resistance to a Maximal Level

July 23, 2014

A Small Amount of Dietary Carbohydrate Can Promote the HFD-Induced Insulin Resistance to a Maximal Level. PlosOne, July 23, 2014. Shuang Mei equal contributor; Xuefeng Yang equal contributor; Huailan Guo; Haihua Gu; Longying Zha; Junwei Cai; Xuefeng Li; Zhenqi Liu; Brian J. Bennett; Ling He; Wenhong Cao.  Author Affiliations: Nutrition Research Institute at Kannapolis, Department of Nutrition, Gillings School […]

Quantitative Trait Loci Affecting Atherosclerosis at the Aortic Root Identified in an Intercross between DBA2J and 129S6 Apolipoprotein E-Null Mice.

February 20, 2014

Quantitative Trait Loci Affecting Atherosclerosis at the Aortic Root Identified in an Intercross between DBA2J and 129S6 Apolipoprotein E-Null Mice. PloS One, February 20, 2014. Kayashima Y, Tomita H, Zhilicheva S, Kim S, Kim HS, Bennett BJ, Maeda N. Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill,  Department of Genetics, University of North Carolina at Chapel […]

Heart and Liver Disease: Deciphering Metabolic and Genetic Connections

June 13, 2013

The human genetic code is 99.9 percent identical. What makes people individuals, genetically speaking, equates to .1 percent of their individual genetic make-up and accounts for thousands of differentiations at the molecular level.  Deciphering those differentiations or polymorphisms and their involvement in the development of disease is the work of scientists like Karen Corbin, PhD, RD, and […]

Heart and Liver Disease: Deciphering Metabolic and Genetic Connections

June 09, 2013

The human genetic code is 99.9 percent identical. What makes people individuals, genetically speaking, equates to .1 percent of their individual genetic make-up and accounts for thousands of differentiations at the molecular level. Deciphering those differentiations or polymorphisms and their involvement in the development of disease is the work of scientists like Karen  Corbin, PhD, RD, […]

Unraveling inflammatory responses using systems genetics and gene-environment interactions in macrophages

October 10, 2012

Unraveling inflammatory responses using systems genetics and gene-environment interactions in macrophages. Cell. October 2012. Orozco LD, Bennett BJ (UNC Chapel Hill Nutrition Research Institute), Farber CR, Ghazalpour A, Pan C, Che N, Wen P, Qi HX, Mutukulu A, Siemers N, Neuhaus I, Yordanova R, Gargalovic P, Pellegrini M, Kirchgessner T, Lusis AJ. Department of Human […]

High-resolution association mapping of atherosclerosis loci in mice.

August 10, 2012

High-resolution association mapping of atherosclerosis loci in mice. Artiosclerosis, Thrombosis, and Vascular Biology, August 2012. Bennett BJ, Orozco L, Kostem E, Erbilgin A, Dallinga M, Neuhaus I, Guan B, Wang X, Eskin E, Lusis AJ. UNC Chapel Hill Nutrition Research Institute. Abstract OBJECTIVE: The purpose of this study was to fine map previously identified quantitative […]