atherosclerosis

Cardiovascular Mechanisms of Action of Anthocyanins May Be Associated with the Impact of Microbial Metabolites on Heme Oxygenase-1 in Vascular Smooth Muscle Cells

June 21, 2018

Warner EF1, Rodriguez-Ramiro I2, O’Connell MA3, Kay CD4. Cardiovascular Mechanisms of Action of Anthocyanins May Be Associated with the Impact of Microbial Metabolites on Heme Oxygenase-1 in Vascular Smooth Muscle Cells. Molecules. 2018 Apr 13;23(4). pii: E898. doi: 0.3390/molecules23040898. Author information 1 Department of Nutrition and Preventative Medicine, Norwich Medical School, Bob Champion Research and Education Building, University of […]

Both rare and common variants in PCSK9 influence plasma low-density lipoprotein cholesterol level in American Indians

November 20, 2014

Both rare and common variants in PCSK9 influence plasma low-density lipoprotein cholesterol level in American Indians. J Clin Endocrinol Metab. 2014 Nov 20, Tsai CW1, North KE, Tin A, Haack K, Franceschini N, Saroja Voruganti V (UNC Nutrition Research Institute), Laston S, Zhang Y, Best LG, MacCluer JW, Beaty TH, Navas-Acien A, Linda Kao WH,Howard BV. Department […]

High-Resolution Genetic Mapping in the Diversity Outbred Mouse Population Identifies Apobec1 as a Candidate Gene for Atherosclerosis

October 23, 2014

High-Resolution Genetic Mapping in the Diversity Outbred Mouse Population Identifies Apobec1 as a Candidate Gene for Atherosclerosis G3 (Bethesda). 2014 Oct 23, Smallwood TL1, Gatti DM2, Quizon P3, Weinstock GM4, Jung KC1, Zhao L1, Hua K1, Pomp D1, Bennett BJ5. University of North Carolina at Chapel Hill; 2The Jackson Laboratory; 3University of North Carolina Nutrition Research Institute; […]

Genetic network identifies novel pathways contributing to atherosclerosis susceptibility in the innominate artery

August 12, 2014

Genetic network identifies novel pathways contributing to atherosclerosis susceptibility in the innominate artery BMC Med Genomics. 2014 Aug 12, Albright J, Quizon PM, Lusis AJ, Bennett BJ. Department of Genetics, Nutrition Research Institute, University of North, Carolina, Chapel Hill, 500 Laureate Way, Suite 2303, Kannapolis, NC 28081, USA Abstract BACKGROUND: Atherosclerosis, the underlying cause of cardiovascular disease, results from both genetic and environmental factors. METHODS: […]

Effect of egg ingestion on trimethylamine-N-oxide production in humans: a randomized, controlled, dose-response study

June 26, 2014

Effect of egg ingestion on trimethylamine-N-oxide production in humans: a randomized, controlled, dose-response study. Jun 26, 2014 The American Journal of Clinical Nutrition. August 2014. Carolyn A Miller, Karen D Corbin, Kerry-Ann da Costa, Shucha Zhang, Xueqing Zhao, Joseph A Galanko, Tondra Blevins, Brian J Bennett, Annalouise O’Connor, and Steven H Zeisel. The Nutrition Research Institute, University of North Carolina at Chapel Hill, […]

Comparative Genome-Wide Association Studies in Mice and Humans for Trimethylamine N-Oxide, a Proatherogenic Metabolite of Choline and L-Carnitine.

March 27, 2014

Comparative Genome-Wide Association Studies in Mice and Humans for Trimethylamine N-Oxide, a Proatherogenic Metabolite of Choline and L-Carnitine. Arteriosclerosis, thrombosis, and vascular biology. Mar 27, 2014. [Epub ahead of print] Hartiala J1, Bennett BJ, Tang WH, Wang Z, Stewart AF, Roberts R, McPherson R; CARDIoGRAM Consortium, Lusis AJ, Hazen SL, Allayee H. From the Department of Preventive Medicine (J.H., H.A.) and Institute for Genetic Medicine (J.H., […]

Heart and Liver Disease: Deciphering Metabolic and Genetic Connections

June 13, 2013

The human genetic code is 99.9 percent identical. What makes people individuals, genetically speaking, equates to .1 percent of their individual genetic make-up and accounts for thousands of differentiations at the molecular level.  Deciphering those differentiations or polymorphisms and their involvement in the development of disease is the work of scientists like Karen Corbin, PhD, RD, and […]

Paeonol attenuates high-fat-induced atherosclerosis in rabbits by anti-inflammatory activity

March 19, 2009

Li, H., Dai, M.,Jia, W. Paeonol attenuates high-fat-induced atherosclerosis in rabbits by anti-inflammatory activity, Planta Medica, 75(1), 7-11, 2009. Abstract Cortex Moutan (Paeonia suffruticosa Andrews, Ranunculaceae) has several uses in traditional medicine, such as analgesic, antipyretic, and anti-inflammatory applications and use in the prevention of thromboembolic diseases. Paeonol, a main active component in Cortex Moutan, […]