Appalachian State

Post-exercise skeletal muscle glycogen related to plasma cytokines and muscle IL-6 protein content, but not muscle cytokine mRNA expression

August 26, 2015

Post-exercise skeletal muscle glycogen related to plasma cytokines and muscle IL-6 protein content, but not muscle cytokine mRNA expression, Frontiers in Nutrition, 26 Aug 2015, David C. Nieman1* 1Appalachian State University, USA Abstract Objectives: The purpose of this study was to correlate post-exercise muscle glycogen levels with changes in plasma cytokine, and muscle mRNA cytokine […]

Rhodiola rosea Exerts Antiviral Activity in Athletes Following a Competitive Marathon Race

July 31, 2015

Rhodiola rosea Exerts Antiviral Activity in Athletes Following a Competitive Marathon Race, Front. Nutr., 31 July 2015, Maryam Ahmed1*, Dru A. Henson1, Matthew C. Sanderson1, David C. Nieman2, Jose M. Zubeldia3 and R. Andrew Shanely4 1Department of Biology, Appalachian State University, Boone, NC, USA 2Human Performance Laboratory, Appalachian State University, Kannapolis, NC, USA 3PoliNat SL, Las Palmas, […]

No Positive Influence of Ingesting Chia Seed Oil on Human Running Performance

May 15, 2015

No Positive Influence of Ingesting Chia Seed Oil on Human Running Performance, 15 May 2015,  Nutrients , David C. Nieman 1,*, Nicholas D. Gillitt 2, Mary Pat Meaney 1 and Dustin A. Dew Human Performance Laboratory, Appalachian State University, North Carolina Research Campus, Kannapolis, NC 28081, USA; E-Mails: meaneymp@appstate.edu (M.P.M.); dustindew@gmail.com (D.A.D.) Dole Nutrition Research Laboratory, […]

Ultrasonic assessment of exercise-induced change in skeletal muscle glycogen content

April 18, 2015

Ultrasonic assessment of exercise-induced change in skeletal muscle glycogen content, 2015 Apr 18, BMC Sports Sci Med Rehabil. Nieman DC1, Shanely RA2, Zwetsloot KA2, Meaney MP1, Farris GE3. 1Appalachian State University, Human Performance Lab, North Carolina Research Campus, 600 Laureate Way, Kannapolis, NC 28081 USA. 2Department of Health and Exercise Science, Appalachian State University, Boone, NC USA. 3Department […]

Adiposity, Aerobic and Anaerobic Fitness in Middle School Aged Children

April 07, 2015

Adiposity, Aerobic and Anaerobic Fitness in Middle School Aged Children,  Apr 2015 ,The FASEB Journal, David Nieman1, Dustin Dew1 and Pamela Krasen1 1North Carolina Research Campus Appalachian State University Kannapolis NC United States Abstract National data suggest that aerobic fitness and adiposity are negatively correlated in children, but this relationship was established using submaximal exercise tests and skinfold […]

Chia Seed Oil Supplementation Has No Influence on Running Performance

April 02, 2015

Chia Seed Oil Supplementation Has No Influence on Running Performance, The FASEB Journal, April 2015, David Nieman1, Nicholas Gillitt2, Mary Pat Meaney1, Dustin Dew1 and Fuxia Jin2 1NCRC Appalachian State University United States 2Dole Nutrition Research Laboratory Dole Foods United States Chia Seed Oil Supplementation Has No Influence on Running Performance Abstract Plasma ALA levels peak about 2 h after ingestion, […]

Cytokine expression and secretion by skeletal muscle cells: regulatory mechanisms and exercise effects

February 24, 2015

Cytokine expression and secretion by skeletal muscle cells: regulatory mechanisms and exercise effects, Queensland University, Feb 2015, Jonathan M. Peake1, Paul Della Gatta2, Katsuhiko Suzuki3, David C. Nieman4 Affiliations: 1 School of Biomedical Sciences and Institute of Health and Biomedical Sciences, Queensland University of Technology, Brisbane, Australia 2 Centre for Physical Activity and Nutrition, School of Exercise and […]

Influence of Pistachios on Performance and Exercise-Induced Inflammation, Oxidative Stress, Immune Dysfunction, and Metabolite Shifts in Cyclists: A Randomized, Crossover Trial.

November 19, 2014

Influence of Pistachios on Performance and Exercise-Induced Inflammation, Oxidative Stress, Immune Dysfunction, and Metabolite Shifts in Cyclists: A Randomized, Crossover Trial. PLoS One. 2014 Nov 19, Nieman DC1, Scherr J2, Luo B3, Meaney MP1, Dréau D4, Sha W5, Dew DA1, Henson DA6, Pappan KL7. Appalachian State University, Human Performance Lab, North Carolina Research Campus, Kannapolis, NC, United States of America. 2Department of Prevention and […]

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique

September 10, 2014

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique JoVE Clinical and Translational Medicine, Sept 10, 2014, R. Andrew Shanely1,2, Kevin A. Zwetsloot2, N. Travis Triplett2, Mary Pat Meaney1,2, Gerard E. Farris3, David C. Nieman Human Performance Laboratory, North Carolina Research Campus, Appalacian State University, 2College of Health Sciences, Appalachian State University, 3Department of Emergency Medicine, […]

The Metabolite Profiles of the Obese Population Are Gender-Dependent

August 17, 2014

The Metabolite Profiles of the Obese Population Are Gender-Dependent J Proteome Res. 2014 Aug 17, Xie G, Ma X, Zhao A, Wang C, Zhang Y, Nieman D, Nicholson JK, Jia W, Bao Y, Jia W. Shanghai Key Laboratory of Diabetes Mellitus and Center for Translational Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai 200233, China. Appalachian State University Human Performance Laboratory Abstract Recent studies have […]

The Protective Effects of a Polyphenol-Enriched Protein Powder on Exercise-Induced Susceptibility to Virus Infection

August 02, 2014

The Protective Effects of a Polyphenol-Enriched Protein Powder on Exercise-Induced Susceptibility to Virus Infection Phytother Res. 2014 Aug 2, Ahmed M1, Henson DA, Sanderson MC, Nieman DC, Gillitt ND, Lila MA. Department of Biology, Appalachian State University, Boone, NC, 28608, USA. Abstract Prolonged and intensive exercise induces transient immunosuppression and is associated with an increased risk and severity of infections. The goal of […]

Metabolomics approach to assessing plasma 13- and 9-hydroxy-octadecadienoic acid

April 23, 2014

Am J Physiol Regul Integr Comp Physiol. 2014 Apr 23. [Epub ahead of print] Metabolomics approach to assessing plasma 13- and 9-hydroxy-octadecadienoic acid and linoleic acid metabolite responses to 75-km cycling. Nieman DC, Shanely RA, Luo B, Meaney MP, Dew DA, Pappan KL. Appalachian State University Human Performance Laboratory, NC Research Campus. Abstract Bioactive oxidized linoleic acid metabolites (OXLAMs) include 13- […]

NASCAR’s Hendrick Motorsports Leaves Its Mark on Science

January 25, 2014

Hendrick Motorsports in Concord, NC, is one of NASCAR’s premier teams. They are not only leaving their mark in the annals of motor sports, they are leaving their mark on science. Hendrick Motorsports is home to four of the most recognized names in racing: Kasey Kahne, Jeff Gordon, Jimmie Johnson and Dale Earnhardt Jr. Cumulatively, […]

High-intensity interval training induces a modest systemic inflammatory response in active, young men.

January 09, 2014

High-intensity interval training induces a modest systemic inflammatory response in active, young men. Journal of Inflammation Research. January, 9, 2014. eCollection. Zwetsloot KA, John CS, Lawrence MM, Battista RA, Shanely RA. Department of Health, Leisure, and Exercise Science, Appalachian State University, Boone, NC; Human Performance Laboratory, North Carolina Research Campus, Appalachian State University. Abstract THE […]

Vitamin D2 Supplementation Amplifies Eccentric Exercise-Induced Muscle Damage in NASCAR Pit Crew Athlete

December 06, 2013

Vitamin D2 Supplementation Amplifies Eccentric Exercise-Induced Muscle Damage in NASCAR Pit Crew Athletes. Nutrients 2014. December 2013. David C. Nieman, Nicholas D. Gillitt, R. Andrew Shanely, Dustin Dew, Mary Pat Meaney and Beibei Luo. Human Performance Laboratory, Appalachian State University, North Carolina Research Campus, Kannapolis; Dole Nutrition Research Laboratory, North Carolina Research Campus, Kannapolis; Key […]

The Effects of Moderate Exercise on Chronic Stress-Induced Intestinal Barrier Dysfunction and Antimicrobial Defense.

November 27, 2013

The Effects of Moderate Exercise on Chronic Stress-Induced Intestinal Barrier Dysfunction and Antimicrobial Defense. Brain, Behavior, and Immunity. Nov 27, 2013. [Epub ahead of print] Luo B, Xiang D, Nieman DC (ASU Human Performance Lab at the NC Research Campus), Chen P. Key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University […]

Influence of vitamin D mushroom powder supplementation on exercise-induced muscle damage in vitamin D insufficient high school athletes

October 06, 2013

Influence of vitamin D mushroom powder supplementation on exercise-induced muscle damage in vitamin D insufficient high school athletes. Journal of Sports Sciences. October 2013. Shanely RA, Nieman DC, Knab AM, Gillitt ND, Meaney MP, Jin F, Sha W, Cialdella-Kam L. Human Performance Laboratory, Appalachian State University, NC Research Campus, Kannapolis , NC. Abstract Abstract Incidence of vitamin D deficiency is increasing worldwide. The purpose […]

Intense Workouts Cause Runners More Physical Damage Than Cyclists

October 03, 2013

  New scientific findings give endurance runners a reason to consider varying their training regime to include other sports. The study, Immune and Inflammation Responses to a 3-day Period of Intensified Running Versus Cycling, was conducted by the Appalachian State University (ASU) Human Performance Laboratory at the North Carolina Research Campus in Kannapolis. After a […]

For Kids, a Little Exercise Goes a Long Way Fast to Prevent Disease

September 20, 2013

    Studies by the Appalachian State University (ASU) Human Performance Laboratory at the NC Research Campus prove that when kids increase their level of physical activity, they experience positive health benefits quickly. Benefits like less body fat, increased muscular strength and reduced risk factors for major diseases like diabetes, cardiovascular disease and other metabolic […]

Immune and inflammation responses to a 3-day period of intensified running versus cycling.

September 19, 2013

Immune and inflammation responses to a 3-day period of intensified running versus cycling.  Brain, Behavior and Immunity. September 19, 2013. Nieman DC, Luo B, Dréau D, Henson DA, Shanely RA, Dew D, Meaney MP. Human Performance Laboratory, Appalachian State University, North Carolina Research Campus, Kannapolis, NC. Abstract Functional overreaching has been linked to alterations in immunity and host pathogen defense, but […]