Slavko Komarnytsky Search Results

Appalachian Trail hike could lead to scientific discovery

By Marty Price, Charlotte Observer Read the original story. Jessica Alley, a part-time research technician at the North Carolina Research Campus in Kannapolis, has wanted to hike the entire Appalachian Trail since she was in middle school, and she finally decided that 2015 would be the year. Having earned her master’s degree in exercise science […]

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STEM enrichment part of Cabarrus STARS summer camp

In early June, two middle school boys got in trouble at school for threatening each other during end-of-grade testing. The conflict could have festered over the summer and led to future disrespect and consequential disciplinary action; instead, these young men have been able to settle their differences thanks to their willingness to grow as individuals […]

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Cabarrus County STEM educators get hands-on at the Plants for Human Health Institute

KANNAPOLIS, N.C. – Field trips are opportunities to enhance the educational environment by going outside the classroom, and having a little fun. STEMersion offers teachers a week of field trips to local STEM-related businesses and organizations. On Tuesday, July 7, 2015, 26 Cabarrus County educators participating in STEMersion will enjoy a field trip to the […]

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Alaskan seaweeds lower inflammation in RAW 264.7 macrophages and decrease lipid accumulation in 3T3-L1 adipocytes

Alaskan seaweeds lower inflammation in RAW 264.7 macrophages and decrease lipid accumulation in 3T3-L1 adipocytes, 14 Apr 2015, Journal of Functional Foods. Joshua Kellogg, Debora Esposito, Mary H. Grace, Slavko Komarnytsky, Mary Ann Lila NC State University Abstract Chronic inflammation is characterized by macrophage accumulation in adipose tissue, which subsequently up-regulates pro-inflammatory cytokines and promotes the dysregulation of lipid metabolism, […]

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Diverse Classes of Bitter Phytochemicals Modulate Carbohydrate Metabolism and Immune Responses through Gastrointestinal Bitter Taste Receptors

Diverse Classes of Bitter Phytochemicals Modulate Carbohydrate Metabolism and Immune Responses through Gastrointestinal Bitter Taste Receptors, Apr 2015, The FASEB Journal, Kimberly Palatini1,2, Mickey Wilson1,2, Jessica Alley1,3, Debora Esposito1,2 and Slavko Komarnytsky1,2 1Plants for Human Health Institute North Carolina State University Kannapolis NC United States 2Food, Bioprocessing, and Nutrition Sciences North Carolina State University Raleigh NC United States 3Health and Exercise […]

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Research Campus in Kannapolis helps 8th-grader with science fair experiment

By: Marty Price, Charlotte Observer Aarushi Patil, a 13-year-old in the eighth grade at Metrolina Regional Scholars Academy of Charlotte, likes to excel at her school’s science fair. The daughter of Vishal and Neetu Patil of Charlotte, Aarushi advanced to the state finals of the 2014 N.C. Science and Engineering Fair with her experiment – […]

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13-Year Old Scientist Tackles Cholesterol at NCRC

In the lab of Slavko Komarnytsky, PhD, assistant professor in pharmacogenomics at the NC State Plants for Human Health Institute (PHHI) on the NC Research Campus in Kannapolis, research revolves around the study of natural compounds in plants and their effect on metabolic, inflammatory and infective diseases. On Wednesday, January 7, 13-year-old Aarushi Patil brought […]

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Making Healthy ‘Grits’ in Africa with Dr. Mary Ann Lila

By: David Hunt, Carolina Wild Nearly 8,000 miles, an ocean and seven time zones separate the small town of Kannapolis, N.C. from the heartland of southern Africa. Food scientist Mary Ann Lila knows the distance all too well. She’s visited 17 African countries in the past eight years. But she doesn’t measure the distance solely in miles. […]

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Activation of pattern recognition receptors in brown adipocytes induces inflammation and suppresses uncoupling protein 1 expression and mitochondrial respiration

Activation of pattern recognition receptors in brown adipocytes induces inflammation and suppresses uncoupling protein 1 expression and mitochondrial respiration. American Journal of Physiology.  Cell Physiology. May 15, 2014. Epub 2014 Mar 13. Bae J1, Ricciardi CJ1, Esposito D2, Komarnytsky S2, Hu P1, Curry BJ1, Brown PL1, Gao Z3, Biggerstaff JP4, Chen J5, Zhao L6. 1Department of Nutrition, University of Tennessee, Knoxville, Tennessee; 2Plants for Human Health […]

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Reaping a Healthy Harvest

<!– ­http://research.ncsu.edu/results/2014/04/healthy-harvest/ By David Hunt Nearly 8,000 miles, an ocean and seven time zones separate the small town of Kannapolis, N.C. from the heartland of southern Africa. Food scientist Mary Ann Lila knows the distance all too well. She’s visited 17 African countries in the past eight years. But she doesn’t measure the distance solely […]

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Diabetes and Bioactives

A generation ago, the prevailing opinion was that once a person became obese they would develop type 2 diabetes. Today, scientists like Slavko Komarnytsky, PhD, assistant professor of pharmacogenomics with the NC State University Plants for Human Health Institute, research the genetic differences that cause obesity, diabetes and other metabolic disorders. They are trying to find […]

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Kannapolis study could separate link between obesity, diabetes

  Jenna Barnes, News 14 Carolina View the video. KANNAPOLIS — Health officials say diabetes is one of the health risks associated with obesity. Scientists at the North Carolina Research Campus believe more than half of all obese people eventually develop the disease. “Some may develop it immediately, some it may take ten to fifteen […]

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Tracking Parallel Pathways of Obesity, Diabetes and Inflammation

A generation ago, the prevailing opinion was that once a person became obese they would develop type 2 diabetes. Today, scientists like Slavko Komarnytsky, PhD, assistant professor of pharmacogenomics with NC State University (NCSU) Plants for Human Health Institute (PHHI) at the NC Research Campus (NCRC), know that obesity and diabetes are related but that […]

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A Visit to an “Emerald City” of Science

Across the country, academic scientists are struggling with tight budgets for equipment and staff. In the North Carolina Piedmont town of Kannapolis, however, researchers affiliated with half a dozen universities and several corporations work in bright, modern laboratory buildings whose decor, equipment, and scientific resources verge on the lavish. Once the home of Cannon Towels, […]

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Pregnane glycosides interfere with steroidogenic enzymes to down-regulate corticosteroid production in human adrenocortical H295R cells

Pregnane glycosides interfere with steroidogenic enzymes to down-regulate corticosteroid production in human adrenocortical H295R cells. Journal of Cellular Physiology. October 2012. Komarnytsky S, Esposito D, Poulev A, Raskin I. Rutgers University and NC State University Plants for Human Health Institute. Abstract A group of bioactive steroidal glycosides (pregnanes) with anorectic activity in animals was isolated […]

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Brassica Breakthroughs

Research conducted at the NC State University Plants for Human Health Institute (PHHI) has resulted in a range of findings from the development of a functional food powder to the genome sequencing of the blueberry to recent findings revealing the benefits of plant steroids. Specifically, the brassinosteroid homobrassinolide, which is found in all plants and regulates growth […]

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Hypoglycemic effects of brassinosteroid in diet-induced obese mice

Hypoglycemic effects of brassinosteroid in diet-induced obese mice. Amerian Journal of Physiology, Endriconology and Metabolism. September 2012. Esposito D, Kizelsztein P, Komarnytsky S, Raskin I. North Carolina State University Plants for Human Health Institute. Abstract The prevalence of obesity is increasing globally, and obesity is a major risk factor for metabolic diseases such as type […]

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Vegetable steroids build up muscle mass

Leah Chester-Davis, North Carolina State University   Mustard greens and cabbage could very well be back-up plants for Popeye’s spinach when it comes to building muscles and increasing physical performance. Recent studies show that brassinosteroids present in mustard and other Brassica plants such as cabbage or broccoli trigger a physiological response in rats that is […]

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Research: Greens could build muscle

The Salisbury Post KANNAPOLIS — Researchers working for N.C. State University in Kannapolis have shown mustard greens and cabbage could be back-up plants for Popeye’s spinach when it comes to building muscles and increasing physical performance. Recent studies at the NCSU Plants for Human Health Institute at the N.C. Research Campus show that compounds called […]

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Plant Steroids Hold Promise for Increase in Muscle Mass and Physical Performance

Plants for Human Health Institute Mustard greens and cabbage could very well be back-up plants for Popeye’s spinach when it comes to building muscles and increasing physical performance.  Recent studies show that brassinosteroids present in mustard and other Brassica plants such as cabbage or broccoli trigger a physiological response in rats that is similar to […]

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Dr. Slavko Komarnytsky Contributes Chapter to New Book

A North Carolina State University professor is one of the authors of a new book about using antibodies to deliver drugs more accurately to diagnose and treat various diseases. Dr. Slavko Komarnytsky, a metabolic biologist and assistant professor with the N.C. State University Department of Food, Bioprocessing and Nutrition Sciences and the Plants for Human […]

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