Appalachian State

Men with Achy Knees Needed for Research Study

February 09, 2017

The Appalachian State University Human Performance Laboratory needs 26 men between the ages of 50 and 75 with achy knees for a study examining the effectiveness of a product made from natural ingredients on knee discomfort. Those who complete the study earn $300.

Image credit: US News Health

Since 32 percent of all U.S. adults report joint discomfort that gets worse with age, scientists at the Appalachian State University Human Performance Laboratory know that there are men out there between 50 and 75 with achy knees. Those men can earn some extra cash by taking part in a 12-week research study looking at the effect a supplement made from natural ingredients has on knee discomfort.

The study, “Influence of Instaflex Advanced supplement on joint function:  a randomized, placebo-controlled community trial”, begins March 13.

“After we sent out our initial recruitment emails, we quickly recruited 40 women with knee pain,” said David Nieman, DrPH, director of the Human Performance Laboratory. “We still need 26 men to reach a total of 66 study participants.”

The study will examine the effect of ingesting 12-weeks of the Instaflex Advanced supplement on knee discomfort versus taking a placebo. The supplement is made from turmeric, resveratrol, Boswellia serrata, collagen, hyaluronic acid, and black pepper extract. Several of these natural ingredients are known for having anti-inflammatory properties. Participants will visit the Human Performance Laboratory four times during the study period. Those who finish the study will receive $300 as compensation for their time.

Dr. David Nieman

Besides being an older gentleman who has suffered discomfort in the knee joint in the last three months, study participants will need to avoid the use of non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or aspirin, and other pain supplements and medications for two weeks before the study begins and throughout its duration.  Participants must also maintain their weight during the study. Additionally, they cannot have serious medical or mental conditions that will interfere with finishing study or the results, including cancer, congestive heart failure, ulcers, kidney disease, severe rheumatoid arthritis or a recent heart attack or stroke.

“Conventional treatment of alleviating joint discomfort with NSAIDs and other types of drugs is often linked to undesirable side effects,” Nieman commented.
“Use of alternative supplements is reported by half of individuals with knee discomfort, and well-designed human trials are needed to identify the most effective alternatives.  This study will help provide important scientific evidence on the usefulness of the Instaflex Advanced product in improving joint function.”

To sign-up or receive additional information, email or call 704-250-5352.



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