Journal Articles

DMBA promotes ErbB2‑mediated carcinogenesis via ErbB2 and estrogen receptor pathway activation and genomic instability

Zhikun Ma, Young Mi Kim, Erin W. Howard, Xiaoshan Feng, Stanley D. Kosanke, Shihe Yang, Yunbo Jiang, Amanda B. Parris, Xia Cao, Shibo Li, Xiaohe Yang. DMBA promotes ErbB2‑mediated carcinogenesis via ErbB2 and estrogen receptor pathway activation and genomic instability. Oncology Reports. July 4, 2018. Author Affiliations Department of Pathology, University of Oklahoma Health Sciences Center, […]

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Recent advances in banana (Musa spp.) biofortification to alleviate vitamin A deficiency

Delphine Amah, Angeline van Biljon, Allan Brown, Penelope Perkins-Veazie, Rony Swennen & Maryke Labuschagne. Recent advances in banana (Musa spp.) biofortification to alleviate vitamin A deficiency. Critical Reviews in Food Science and Nutrition. Received 21 May 2018, Accepted 27 Jun 2018, Accepted author version posted online: 12 Jul 2018. Author Affiliations Department of Plant Sciences (Plant Breeding), University of the Free State, Bloemfontein, […]

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The Bioavailability, Transport, and Bioactivity of Dietary Flavonoids: A Review from a Historical Perspective

Gary Williamson, Colin D. Kay, and Alan Crozier. The Bioavailability, Transport, and Bioactivity of Dietary Flavonoids: A Review from a Historical Perspective. Comprehensive Reviews in Food Science and Food Safety. First published: 10 July 2018.  Author Affiliations School of Food Science, Univ. of LeedsLeeds, U.K Food Bioprocessing and Nutrition Sciences, Plants for Human Health Inst., North Carolina State Univ., […]

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Prediction of swelling behavior of crosslinked maize starch suspensions

Gnana PrasunaDesam, Jinsha Lia, Guibing Chen, Osvaldo Campanella, Ganesan Narsimhana. Prediction of swelling behavior of crosslinked maize starch suspensions. Carbohydrate Polymers. Available online 9 July 2018. © 2018 Elsevier Ltd. Author Affiliations Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN 47907, United States Center for Excellence in Post-Harvest Technology, North Carolina A&T […]

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Avenanthramide Aglycones and Glucosides in Oat Bran: Chemical Profile, Levels in Commercial Oat Products, and Cytotoxicity to Human Colon Cancer Cells

Wenbin Wu, Yao Tang, Junli Yang, Emmanuel Idehen, and Shengmin Sang. Avenanthramide Aglycones and Glucosides in Oat Bran: Chemical Profile, Levels in Commercial Oat Products, and Cytotoxicity to Human Colon Cancer Cells. J. Agric. Food Chem. DOI: 10.1021/acs.jafc.8b02767. Publication Date (Web): July 9, 2018. Copyright © 2018 American Chemical Society. Author Affiliation Laboratory for Functional Foods and Human Health, Center for Excellence in Post–Harvest Technologies, North […]

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CHIP E3 ligase mediates proteasomal degradation of the proliferation regulatory protein ALDH1L1 during the transition of NIH3T3 fibroblasts from G0/G1 to S-phase

Qasim A. Khan, Peter Pediaditakis, Yuryi Malakhau, Amin Esmaeilniakooshkghazi, Zahra Ashkavand, Valentin Sereda, Natalia I. Krupenko, Sergey A. Krupenko. CHIP E3 ligase mediates proteasomal degradation of the proliferation regulatory protein ALDH1L1 during the transition of NIH3T3 fibroblasts from G0/G1 to S-phase. PLOS One Published: July 6, 2018. https://doi.org/10.1371/journal.pone.0199699 Author Affiliations Nutrition Research Institute, University of North Carolina […]

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Implementation of a Regional Network for ST‐Segment–Elevation Myocardial Infarction (STEMI) Care and 30‐Day Mortality in a Low‐ to Middle‐Income City in Brazil: Findings From Salvador’s STEMI Registry (RESISST)

Nivaldo Menezes Filgueiras Filho, Gilson Soares Feitosa Filho, Davi Jorge Fontoura Solla, Felipe Coelho Argôlo, Patrícia Oliveira Guimarães, Ivan de Mattos Paiva Filho, Larissa Gordilho Mutti Carvalho, Larissa Silva Teixeira, Marcos Nogueira de Oliveira Rios, Sergio Figueiredo Câmara, Victor Oliveira Novais, Leonardo de Souza Barbosa, Constance Silva Ballalai, Carolina Vitoria De Lúcia, Christopher B. Granger, L. Kristin Newby, Renato D. Lopes. Implementation of a Regional Network for ST‐Segment–Elevation Myocardial Infarction (STEMI) […]

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Trapping of glyoxal by propyl, octyl and dodecyl gallates and their mono-glyoxal adducts

Yu Houa, Zhengjun Xie, Hengqing Cuia Yongling Lu,Tiesong Zheng, Shengmin Sang, Lisuang Lv. Trapping of glyoxal by propyl, octyl and dodecyl gallates and their mono-glyoxal adducts. Food Chemistry. Volume 269, 15 December 2018, Pages 396-403 Received 22 April 2018, Revised 2 July 2018, Accepted 3 July 2018, Available online 4 July 2018. Author Affiliation A Department […]

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Examination of muscle morphology and neuromuscular function in normal weight and overfat children aged 7 to 10 years

Trent J. Herda, Eric D. Ryan, Martin Kohlmeier, Michael A. Trevino, Gena R. Gerstner, Erica J. Roelofs.  Examination of muscle morphology and neuromuscular function in normal weight and overfat children aged 7 to 10 years. Scandinavian Journal of Medicine & Science in Sports. https://doi.org/10.1111/sms.13256 First published: 30 June 2018 Author Affiliations Neuromechanics Laboratory, University of KansasLawrence, […]

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Heritability and genetic correlations of heart rate variability at rest and during stress in the Oman Family Study

Muñoz ML1, Jaju D2, Voruganti S3, Albarwani S2, Aslani A1, Bayoumi R4, Al-Yahyaee S2, Comuzzie AG5, Millar PJ6,7, Picton P7, Floras JS7, Nolte I1, Hassan MO2, Snieder H1. Heritability and genetic correlations of heart rate variability at rest and during stress in the Oman Family Study. J Hypertens. 2018 Jul;36(7):1477-1485. doi: 10.1097/HJH.0000000000001715. Author information 1 Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. 2 […]

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Arsenic-gene interactions and beta-cell function in the Strong Heart Family Study

Balakrishnan P1, Navas-Acien A1, Haack K2, Vaidya D3, Umans JG4, Best LG5, Goessler W6, Francesconi KA6, Franceschini N7, North KE7, Cole SA2, Voruganti VS8, Gribble MO9. Arsenic-gene interactions and beta-cell function in the Strong Heart Family Study. Toxicol Appl Pharmacol. 2018 Jun 1;348:123-129. doi: 10.1016/j.taap.2018.03.034. Epub 2018 Apr 3. Author information 1 Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY, United […]

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Serum Lipid Concentrations and FADS Genetic Variants in Young Mexican College Students: The UP-AMIGOS Cohort Study

Vazquez-Vidal I1,2, Voruganti VS2, Hannon BA3, Andrade FCD4, Aradillas-García C5, Nakamura MT1,3, Terán-García M1,3,6. Serum Lipid Concentrations and FADS Genetic Variants in Young Mexican College Students: The UP-AMIGOS Cohort Study. Lifestyle Genom. 2018 May 30:1-9. doi: 10.1159/000488085. [Epub ahead of print] Author information 1 Department of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA. 2 Department of […]

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Dual effects of propyl gallate and its methylglyoxal adduct on carbonyl stress and oxidative stress.

Cui H1, Tao F2, Hou Y1, Lu Y1, Zheng T1, Sang S3, Lv L4. Dual effects of propyl gallate and its methylglyoxal adduct on carbonyl stress and oxidative stress. Food Chem. 2018 Nov 1;265:227-232. doi: 10.1016/j.foodchem.2018.04.045. Epub 2018 Apr 16. Author information 1 Department of Food Science and Technology, Nanjing Normal University, 122# Ninghai Road, Nanjing 210097, PR China. 2 College of […]

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A new method to prepare and redefine black tea thearubigins

Wang W1, Zhang S1, Lv L2, Sang S3. A new method to prepare and redefine black tea thearubigins. J Chromatogr A. 2018 Aug 17;1563:82-88. doi: 10.1016/j.chroma.2018.05.060. Epub 2018 May 28. Author information 1 Laboratory for Functional Foods and Human Health, Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus, 500 Laureate […]

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Correlated metabolomic, genomic, and histologic phenotypes in histologically normal breast tissue

Sun X1, Stewart DA2, Sandhu R3, Kirk EL1, Pathmasiri WW2, McRitchie SL2, Clark RF4, Troester MA1,3,5, Sumner SJ2. Correlated metabolomic, genomic, and histologic phenotypes in histologically normal breast tissue. PLoS One. 2018 Apr 18;13(4):e0193792. doi: 10.1371/journal.pone.0193792. eCollection 2018. Author information 1 Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America. 2 National Institutes of Health […]

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Botanical Provenance of Traditional Medicines From Carpathian Mountains at the Ukrainian-Polish Border

Kozlowska W1, Wagner C2,3, Moore EM2,4, Matkowski A1, Komarnytsky S2,5. Botanical Provenance of Traditional Medicines From Carpathian Mountains at the Ukrainian-Polish Border. Front Pharmacol. 2018 Apr 5;9:295. doi: 10.3389/fphar.2018.00295. eCollection 2018. Author information 1 Department of Pharmaceutical Biology, Medical University of Wroclaw, Wroclaw, Poland. 2 Plants for Human Health Institute, North Carolina State University, Kannapolis, NC, United States. 3 Department […]

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Cardiovascular Mechanisms of Action of Anthocyanins May Be Associated with the Impact of Microbial Metabolites on Heme Oxygenase-1 in Vascular Smooth Muscle Cells

Warner EF1, Rodriguez-Ramiro I2, O’Connell MA3, Kay CD4. Cardiovascular Mechanisms of Action of Anthocyanins May Be Associated with the Impact of Microbial Metabolites on Heme Oxygenase-1 in Vascular Smooth Muscle Cells. Molecules. 2018 Apr 13;23(4). pii: E898. doi: 0.3390/molecules23040898. Author information 1 Department of Nutrition and Preventative Medicine, Norwich Medical School, Bob Champion Research and Education Building, University of […]

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Peanut flour aggregation with polyphenolic extracts derived from peanut skin inhibits IgE binding capacity and attenuates RBL-2H3 cells degranulation via MAPK signaling pathway

Bansode RR1, Plundrich NJ2, Randolph PD1, Lila MA2, Williams LL3. Peanut flour aggregation with polyphenolic extracts derived from peanut skin inhibits IgE binding capacity and attenuates RBL-2H3 cells degranulation via MAPK signaling pathway. Food Chem. 2018 Oct 15;263:307-314. doi: 10.1016/j.foodchem.2018.05.007. Epub 2018 May 3. Author information 1 Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, […]

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Intergenerational response to the endocrine disruptor vinclozolin is influenced by maternal genotype and crossing scheme

Pietryk EW1, Clement K2, Elnagheeb M1, Kuster R2, Kilpatrick K3, Love MI4, Ideraabdullah FY5. Intergenerational response to the endocrine disruptor vinclozolin is influenced by maternal genotype and crossing scheme. Reprod Toxicol. 2018 Jun;78:9-19. doi: 10.1016/j.reprotox.2018.03.005. Epub 2018 Mar 10. Author information 1 Department of Genetics, School of Medicine, University of North Carolina at Chapel Hill, 120 Mason Farm Rd, CB#7264, Chapel Hill, […]

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Leptin Signaling Mediates Obesity-Associated CSC Enrichment and EMT in Preclinical TNBC Models

Bowers LW1,2, Rossi EL1,2, McDonell SB1, Doerstling SS1, Khatib SA1, Lineberger CG1, Albright JE3, Tang X4, deGraffenried LA5, Hursting SD6,2,3. Leptin Signaling Mediates Obesity-Associated CSC Enrichment and EMT in Preclinical TNBC Models. Mol Cancer Res. 2018 May;16(5):869-879. doi: 10.1158/1541-7786.MCR-17-0508. Epub 2018 Feb 16. Author information 1 Department of Nutrition, University of North Carolina, Chapel Hill, North Carolina. 2 Lineberger Comprehensive Cancer Center, University of North […]

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A naturally occurring conditional albino mutant in rice caused by defects in the plastid-localized OsABCI8 transporter

Zeng X1, Tang R1, Guo H1, Ke S1, Teng B2, Hung YH3,4, Xu Z1, Xie XM1, Hsieh TF5,6, Zhang XQ7. A naturally occurring conditional albino mutant in rice caused by defects in the plastid-localized OsABCI8 transporter. Plant Mol Biol. 2017 May;94(1-2):137-148. doi: 10.1007/s11103-017-0598-4. Author information 1 Guangdong Engineering Research Center of Grassland Science, College of Forestry and Landscape Architecture, South China Agricultural University, Guangzhou, 510642, […]

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Potato phenolics impact starch digestion and glucose transport in model systems but translation to phenolic rich potato chips results in only modest modification of glycemic response in humans.

Moser S1, Aragon I1, Furrer A1, Van Klinken JW2, Kaczmarczyk M2, Lee BH3, George J4, Hamaker BR3, Mattes R4, Ferruzzi MG5. Potato phenolics impact starch digestion and glucose transport in model systems but translation to phenolic rich potato chips results in only modest modification of glycemic response in humans. Nutr Res. 2018 Apr;52:57-70. doi: 10.1016/j.nutres.2018.02.001. Author information 1 Dept of Food Science, Purdue University, West […]

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Carotenoid Stability during Dry Milling, Storage, and Extrusion Processing of Biofortified Maize Genotypes

Ortiz D, Ponrajan A, Bonnet JP1, Rocheford T, Ferruzzi MG2. Carotenoid Stability during Dry Milling, Storage, and Extrusion Processing of Biofortified Maize Genotypes. J Agric Food Chem. 2018 May 9;66(18):4683-4691. doi: 10.1021/acs.jafc.7b05706. Author information 1 Department of Agronomy , Universidad Nacional de Colombia , Bogotá , Colombia. 2 Plants for Human Health Institute , North Carolina State University , Kannapolis […]

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Interactions Between Flavonoid-Rich Extracts and Sodium Caseinate Modulate Protein Functionality and Flavonoid Bioaccessibility in Model Food Systems

Elegbede JL1, Li M2, Jones OG3, Campanella OH4, Ferruzzi MG5 Interactions Between Flavonoid-Rich Extracts and Sodium Caseinate Modulate Protein Functionality and Flavonoid Bioaccessibility in Model Food Systems. J Food Sci. 2018 May;83(5):1229-1236. doi: 10.1111/1750-3841.14132. Epub 2018 Apr 27. Author information 1 W.K. Kellogg Inst. of Food and Nutrition Research, 2 Hamblin Ave East, Battle Creek, MI 49017, U.S.A. 2 North Carolina State […]

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Isobaric Labeling of Intact Gangliosides toward Multiplexed LC-MS/MS-Based Quantitative Analysis

Barrientos RC1,2, Zhang Q1,2.Isobaric Labeling of Intact Gangliosides toward Multiplexed LC-MS/MS-Based Quantitative Analysis. Anal Chem. 2018 Feb 20;90(4):2578-2586. doi: 10.1021/acs.analchem.7b04044. Epub 2018 Jan 31. Author information 1 Department of Chemistry and Biochemistry, The University of North Carolina at Greensboro , Greensboro, North Carolina 27412, United States. 2 UNCG Center for Translational Biomedical Research, NC Research Campus , […]

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Prognostic and Practical Validation of Current Definitions of Myocardial Infarction Associated With Percutaneous Coronary Intervention

Tricoci P1, Newby LK2, Clare RM2, Leonardi S3, Gibson CM4, Giugliano RP5, Armstrong PW6, Van de Werf F7, Montalescot G8, Moliterno DJ9, Held C10, Aylward PE11, Wallentin L10, Harrington RA12, Braunwald E5, Mahaffey KW12, White HD13. Prognostic and Practical Validation of Current Definitions of Myocardial Infarction Associated With Percutaneous Coronary Intervention. JACC Cardiovasc Interv. 2018 May 14;11(9):856-864. doi: 10.1016/j.jcin.2018.02.006. Author information 1Duke Clinical Research Institute, Durham, North Carolina. 2 Duke Clinical Research Institute, […]

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Dual antiplatelet therapy for perioperative myocardial infarction following CABG surgery.

Wang A1, Wu A2, Wojdyla D2, Lopes RD3, Newby LK3, Newman MF4, Smith PK5, Alexander JH3. Dual antiplatelet therapy for perioperative myocardial infarction following CABG surgery. Am Heart J. 2018 May;199:150-155. doi: 10.1016/j.ahj.2018.02.006. Epub 2018 Feb 11. Author information 1 Department of Surgery, Duke University Medical Center, Durham, NC. 2 Department of Statistics, Duke Clinical Research Institute, 2400 Pratt St, Durham, NC. 3 […]

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Risk Score to Predict Need for Intensive Care in Initially Hemodynamically Stable Adults With Non-ST-Segment-Elevation Myocardial Infarction.

Fanaroff AC1,2, Chen AY2, Thomas LE2, Pieper KS2, Garratt KN3, Peterson ED4,2, Newby LK4,2, de Lemos JA5, Kosiborod MN6, Amsterdam EA7, Wang TY4,2. Risk Score to Predict Need for Intensive Care in Initially Hemodynamically Stable Adults With Non-ST-Segment-Elevation Myocardial Infarction. J Am Heart Assoc. 2018 May 25;7(11). pii: e008894. doi: 10.1161/JAHA.118.008894. Author information Abstract BACKGROUND: Intensive care unit (ICU) use for initially stable patients presenting with […]

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In vitro mineral nutrition of Curcuma longa L. affects production of volatile compounds in rhizomes after transfer to the greenhouse

El-Hawaz RF1, Grace MH2, Janbey A2, Lila MA2, Adelberg JW3. In vitro mineral nutrition of Curcuma longa L. affects production of volatile compounds in rhizomes after transfer to the greenhouse. BMC Plant Biol. 2018 Jun 18;18(1):122. doi: 10.1186/s12870-018-1345-y. Author information 1 Department of Plant and Environmental Sciences, Clemson University, Clemson, SC, 29634, USA. rabiae@g.clemson.edu. 2 Plants for Human Health Institute, […]

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Anxiety sensitivity mediates the relationship between exercise frequency and anxiety and depression symptomology.

Broman-Fulks JJ1, Abraham CM1, Thomas K1, Canu WH1, Nieman DC2. Anxiety sensitivity mediates the relationship between exercise frequency and anxiety and depression symptomology. Stress Health. 2018 May 23. doi: 10.1002/smi.2810. Author information 1 Department of Psychology, Appalachian State University, Boone, North Carolina, USA. 2 Department of Health and Exercise Sciences, Appalachian State University, Boone, North Carolina, USA. Abstract The anxiolytic […]

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Systematic reconstruction of autism biology from massive genetic mutation profiles.

Luo W1,2, Zhang C3, Jiang YH4, Brouwer CR1,2. Systematic reconstruction of autism biology from massive genetic mutation profiles. Sci Adv. 2018 Apr 11;4(4):e1701799. doi: 10.1126/sciadv.1701799. Author Information 1 Department of Bioinformatics and Genomics, University of North Carolina (UNC) at Charlotte, Charlotte, NC 28223, USA. 2 UNC Charlotte Bioinformatics Service Division, North Carolina Research Campus, Kannapolis, NC 28081, USA. 3 […]

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Feasibility and Acceptability of Maternal Choline Supplementation in Heavy Drinking Pregnant Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

Jacobson SW1,2,3, Carter RC4,5, Molteno CD3, Meintjes EM2,6, Senekal MS7, Lindinger NM2, Dodge NC1, Zeisel SH8, Duggan CP9, Jacobson JL1,2,3. Feasibility and Acceptability of Maternal Choline Supplementation in Heavy Drinking Pregnant Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Alcohol Clin Exp Res. 2018 May 11. doi: 10.1111/acer.13768. 1 Department of Psychiatry and Behavioral Neurosciences , Wayne State University School of Medicine, Detroit, Michigan. 2 Department of Human […]

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Efficacy of Maternal Choline Supplementation During Pregnancy in Mitigating Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

Jacobson SW1,2,3, Carter RC4,5, Molteno CD3, Stanton ME6, Herbert JS7, Lindinger NM2, Lewis CE2, Dodge NC1, Hoyme HE8,9, Zeisel SH10, Meintjes EM2,11, Duggan CP12, Jacobson JL1,2,3Efficacy of Maternal Choline Supplementation During Pregnancy in Mitigating Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.  Alcohol Clin Exp Res. 2018 May 11. doi: 10.1111/acer.13769. 1 Department of Psychiatry and Behavioral Neurosciences, Wayne State […]

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TNFAIP8 promotes prostate cancer cell survival by inducing autophagy

Suryakant Niture1,2, Malathi Ramalinga2, Habib Kedir1,2, Dorrelyn Patacsil2, Samiksha S. Niture3, James Li4, Haresh Mani5, Simeng Suy4, Sean Collins4 and Deepak Kumar1,2,4 TNFAIP8 promotes prostate cancer cell survival by inducing autophagy, Oncotarget. 2018; 9:26884-26899. 1Julius L. Chambers Biomedical Biotechnology Research Institute, North Carolina Central University Durham, 27707 NC, USA 2Cancer Research Laboratory, University of the District of […]

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Quantification of ascorbyl adducts of epigallocatechin gallate and gallocatechin gallate in bottled tea beverages

Wei-Lun Hung, Siyu Wang, Shengmin Sang, Xiaochun Wan, Yu Wang, Chi-Tang Ho (2018). Quantification of ascorbyl adducts of epigallocatechin gallate and gallocatechin gallate in bottled tea beverages. Food Chemistry, 261, 246-352. Author Affiliations Citrus Research and Education Center, Department of Food Science and Human Nutrition, University of Florida, Lake Alfred, FL 33850, USA Department of […]

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Dual Effects of Propyl Gallate and Its Methylglyoxal Adduct on Carbonyl Stress and Oxidative Stress

Hengqing Cui, Fei Tao, Yu Hou, Yongling Lu, Tiesong Zheng, Shengmin Sang, Lishuang Lv (2018). Dual Effects of Propyl Gallate and Its Methylglyoxal Adduct on Carbonyl Stress and Oxidative Stress. Food Chemistry. Author Affiliations Department of Food Science and Technology, Nanjing Normal University, 122# Ninghai Road, Nanjing 210097, PR China Laboratory for Functional Foods and […]

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Arsenic-gene interactions and beta-cell function in the strong heart family study

Poojitha Balakrishnan, Ana Navas-Acien, Karin Haack, Dhananjay Vaidya, Jason G. Umans, Lyle G. Best, Walter Goessler, Kevin A. Francesconi, Nora Franceschini, Kari E. North, Shelley A. Cole, V. Saroja Voruganti, Matthew O.Gribble (2018). Arsenic-gene interactions and beta-cell function in the strong heart family study. Toxicology and Applied Pharmacology. Author Affiliations Department of Environmental Health Sciences, […]

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A new strategy to infer circularity applied to four new complete frog mitogenomes

Denis Jacob Machado, Daniel James, Cory Brouwer, and Taran Grant (2018). A new strategy to infer circularity applied to four new complete frog mitogenomes. Ecology and Evolution, 8, 4011-4018. Author Affiliations Bioinformatics Interunits Graduate Program, University of São Paulo, São Paulo, Brazil Department of Bioinformatics and Genomics, UNC Charlotte, Charlotte, NC, USA UNC Charlotte Bioinformatics […]

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Atmospheric skin aging—Contributors and inhibitors

David McDaniel, Patricia Farris, Giuseppe Valacchi (2018). Atmospheric skin aging—Contributors and inhibitors. Journal of Cosmetic Dermatology, 17(2), 124-137. Author Affiliations McDaniel Laser and Cosmetic Center and McDaniel Institute of Anti‐Aging Research, Virginia Beach, VA, USA Hampton University Skin of Color Research Institute, Hampton, VA, USA School of Science, Hampton University, Hampton, VA, USA Department of […]

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The postural stability of children with foetal alcohol spectrum disorders during one-leg stance: A feasibility study

Yolandi Brink, John Cockcroft, Soraya Seedat, Philip May, Wendy Kalberg, Quinette Louw (2018). The postural stability of children with foetal alcohol spectrum disorders during one-leg stance: A feasibility study. African Journal of Disability, vol. 7. Author Affiliations Division of Physiotherapy, Stellenbosch University, South Africa Department of Psychiatry, Stellenbosch University, South Africa Department of Nutrition, University […]

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Heritability and genetic correlations of heart rate variability at rest and during stress in the Oman Family Study.

Muñoz ML, Jaju D, Voruganti S, Albarwani S, Aslani A, Bayoumi R, Al-Yahyaee S, Comuzzie AG, Millar PJ, Picton P, Floras JS, Nolte I, Hassan MO, Snieder H (2018). Heritability and genetic correlations of heart rate variability at rest and during stress in the Oman Family Study. Journal of Hypertension. Author Affiliations Department of Epidemiology, […]

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Metals Complexes Formed with Oleanolic Acid

Nilton C. Ribeiro, Antonio J. Demuner, Marcelo H. dos Santos, Célia R. A. Maltha, Elson A. de Alvarenga, Slavko Komarnytsky (2018). Metals Complexes Formed with Oleanolic Acid. International Journal of Organic Chemistry, 8(1). Author Affiliations Chemistry Department, Universidade Federal de Viçosa, Avenida Peter Henry Rolfs, s/n Campus Universitário, Viçosa, Minas Gerais, Brazil. IFMT, Rondonópolis, Brazil. […]

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Metabolic recovery from heavy exertion following banana compared to sugar beverage or water only ingestion: A randomized, crossover trial.

Nieman DC, Gillitt ND, Sha W, Esposito D, Ramamoorthy S (2018). Metabolic recovery from heavy exertion following banana compared to sugar beverage or water only ingestion: A randomized, crossover trial. PLoS One, 13(3). Author Affiliations Human Performance Laboratory, Appalachian State University, North Carolina Research Campus, Kannapolis, North Carolina, United States of America. Dole Nutrition Research […]

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Encapsulation and controlled release of retinol from silicone particles for topical delivery

C. Wyatt Shields, John P. White, Erica G. Osta, Jerishma Patel, Shashank Rajkumar, Nickolas Kirby, Jean-Philippe Therrien, Stefan Zauscher (2018). Encapsulation and controlled release of retinol from silicone particles for topical delivery. Journal of Controlled Release. Author Affiliations NSF Research Triangle Materials Research Science and Engineering Center, Duke University, Durham, NC 27708, USA Department of […]

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Non-conventional rottlerin anticancer properties

Maioli, E; Daveri, E; Maellaro, E; Ietta, F; Cresti, L; Valacchi, G (2018). Non-conventional rottlerin anticancer properties. Archives of Biochemistry and Biophysics, vol. 645 (50-53). Author Affiliations Dipartimento di Scienze della Vita, Universita’ di Siena, Via A. Moro, 53100, Siena, Italy University of California Davis, Department of Nutrition and Environmental Toxicology, 2251 Meyer Hall, 450 […]

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Comprehensive transcriptome analyses correlated with untargeted metabolome reveal differentially expressed pathways in response to cell wall alterations

Nathan T. Reem, Han-Yi Chen, Manhoi Hur, Xuefeng Zhao, Eve Syrkin Wurtele, Xu LiLing Li, Olga Zabotina (2018). Comprehensive transcriptome analyses correlated with untargeted metabolome reveal differentially expressed pathways in response to cell wall alterations. Plant Molecular Biology 1-21. Author Affiliations 1.Department of Biochemistry, Biophysics and Molecular Biology Iowa State University Ames USA 2.Department of […]

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Systematic review and directors survey of quality indicators for the cardiovascular intensive care unit

Michael Goldfarb, Lior Bibas, L. Kristin Newby, Timothy D. Henry, Jason Katze, Sean van Diepen, Bojan Cercek (2018). Systematic review and directors survey of quality indicators for the cardiovascular intensive care unit. International Journal of Cardiology. Author Affiliations Division of Pulmonary and Critical Care, Cedars-Sinai Medical Center, Los Angeles, CA, United States Division of Cardiology, […]

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Omega-6/omega-3 fatty acid intake of children and older adults in the U.S.: dietary intake in comparison to current dietary recommendations and the Healthy Eating Index

Kelly W. Sheppard and Carol L. Cheatham (2018). Omega-6/omega-3 fatty acid intake of children and older adults in the U.S.: dietary intake in comparison to current dietary recommendations and the Healthy Eating Index. Lipids in Health and Disease 17:43. Author Affiliations Center for Biobehavioral Health, The Research Institute at Nationwide Children’s Hospital, Columbus, USA Department […]

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A utilitarian comparison of two alcohol use biomarkers with self-reported drinking history collected in antenatal clinics

Philip A. May, Julie M. Hasken, Marlene M. De Vries, Anna-Susan Marais, Julie M. Stegall, Daniel Marsden, Charles D.H. Parry, Soraya Seedat, Barbara Tabachnick (2018). A utilitarian comparison of two alcohol use biomarkers with self-reported drinking history collected in antenatal clinics. Reproductive Toxicology 77(25-32). Author Affiliations: University of North Carolina at Chapel Hill, Nutrition Research […]

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Simultaneous determination of tryptophan and its 31 catabolites in mouse tissues by polarity switching UHPLC-SRM-MS

Guan-yuan Chen, Wei Zhong, Zhanxiang Zhou, Qibin Zhang (2018). Simultaneous determination of tryptophan and its 31 catabolites in mouse tissues by polarity switching UHPLC-SRM-MS. Analytica Chimica Acta. Author Affiliations: Center for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, NC, 28081, USA Department of Nutrition, University of North Carolina […]

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Dual Antiplatelet Therapy for Perioperative Myocardial Infarction Following CABG Surgery

Alice Wang, Angie Wu, Daniel Wojdyla, Renato D. Lopes, L. Kristin Newby, Mark F. Newman, Peter K. Smith, John H. Alexander (2018). Dual Antiplatelet Therapy for Perioperative Myocardial Infarction Following CABG Surgery. American Heart Journal. Author Affiliations Department of Surgery, Duke University Medical Center, Durham, NC Department of Statistics, Duke Clinical Research Institute, 2400 Pratt […]

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Dietary Modulation of the Epigenome

Folami Y. Ideraabdullah and Steven H. Zeisel (2018). Dietary Modulation of the Epigenome. Physiological Reviews 98(2), 667-695. Abstract Epigenetics is the study of heritable mechanisms that can modify gene activity and phenotype without modifying the genetic code. The basis for the concept of epigenetics originated more than 2,000 yr ago as a theory to explain […]

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A community approach to mortality prediction in sepsis via gene expression analysis

Timothy E. Sweeney, Thanneer M. Perumal, Ricardo Henao, Marshall Nichols, Judith A. Howrylak, Augustine M. Choi, Jesús F. Bermejo-Martin, Raquel Almansa, Eduardo Tamayo, Emma E. Davenport, Katie L. Burnham, Charles J. Hinds, Julian C. Knight, Christopher W. Woods, Stephen F. Kingsmore, Geoffrey S. Ginsburg, Hector R. Wong, Grant P. Parnell, Benjamin Tang, Lyle L. Moldawer, […]

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The Association Between Sleeping Time and Metabolic Syndrome Features, Among Older Adults Living in Mediterranean Region: The MEDIS Study

Georgousopoulou, Ekavi N., D’Cunha, Nathan M., Mellor, Duane D., Tyrovolas, Stefanos, Naumovski, Nenad, Foscolou, Alexandra, Bountziouka, Vassiliki, Gotsis, Efthimios, Metallinos, George, Tyrovola, Dimitra, Piscopo, Suzanne, Valacchi Giuseppe, Tsakountakis, Nikos, Zeimbekis, Akis, Tur, Josep-Antoni, Matalas, Antonia-Leda, Polychronopoulos, Evangelos, Lionis, Christos, Sidossis, Labros, Panagiotakos, Demosthenes B., and MEDIS Study Group. “The Association Between Sleeping Time and Metabolic […]

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Metabolic Syndrome and Related Disorders

Georgousopoulou Ekavi N., D’Cunha Nathan M., Mellor Duane D., Tyrovolas Stefanos, Naumovski Nenad, Foscolou Alexandra, Bountziouka Vassiliki, Gotsis Efthimios, Metallinos George, Tyrovola Dimitra, Piscopo Suzanne, Valacchi Giuseppe, Tsakountakis Nikos, Zeimbekis Akis, Tur Josep-Antoni, Matalas Antonia-Leda, Polychronopoulos Evangelos, Lionis Christos, Sidossis Labros, Panagiotakos Demosthenes B., and MEDIS Study Group. Metabolic Syndrome and Related Disorders. February 2018, […]

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Cell-specific cis-natural antisense transcripts (cis-NATs) in the sperm and the pollen vegetative cells of Arabidopsis thaliana

Peng Qin, Ann E. Loraine (2018). Cell-specific cis-natural antisense transcripts (cis-NATs) in the sperm and the pollen vegetative cells of Arabidopsis thaliana. F1000Research 7:93. Author Affiliations Rice Research Institute, Sichuan Agricultural University, Chengdu Wenjiang, Sichuan, 611130, China U.S. Department of Agriculture/Agricultural Research Service and Department of Plant and Microbial Biology, University of California, Berkeley, Albany, […]

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Complexity of Advanced Glycation End Products in Foods: Where Are We Now?

Yingdong Zhu, Hunter Snooks, and Shengmin Sang (2018). Complexity of Advanced Glycation End Products in Foods: Where Are We Now? Journal of Agriculture and Food Chemistry. Author Affiliations Laboratory for Functional Foods and Human Health, Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus, 500 Laureate Way, […]

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HAfTs are novel lncRNA transcripts from aflatoxin exposure

B. Alex Merrick, Justin S. Chang, Dhiral P. Phadke, Meredith A. Bostrom, Ruchir R. Shah, Xinguo Wang, Oksana Gordon, Garron M. Wright (2018). HAfTs are novel lncRNA transcripts from aflatoxin exposure. PLoS ONE 13(1). Author Affiliations Biomolecular Screening Branch, Division National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United […]

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Resveratrol: from diet to topical usage

Veronica Sanda Chedea, Simona Ioana Vicaş, Claudia Sticozzi, Federica Pessina, Maria Frosini, Emanuela Maioli and Giuseppe Valacchi (2018). Resveratrol: from diet to topical usage. Food & Function, 11. Author Affiliations Laboratory of Animal Biology, National Research and Development Institute for Biology and Animal Nutrition, Baloteşti (INCDBNA-IBNA), Calea Bucureşti nr. 1, Balotesti, Romania University of Oradea, […]

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Human microbiota, blood group antigens, and disease

D. Rose Ewald, Susan C.J. Sumner (2018). Human microbiota, blood group antigens, and disease. Systems Biology and Medicine. Author Affiliations Department of Nutrition, University of North Carolina at Chapel Hill, Kannapolis, North Carolina Abstract Far from being just “bugs in our guts,” the microbiota interacts with the body in previously unimagined ways. Research into the […]

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Metabolism and pharmacokinetics of resveratrol and pterostilbene

Pei Wang, Shengmin Sang (2018). Metabolism and pharmacokinetics of resveratrol and pterostilbene. BioFactors. Author Affiliations Laboratory for Functional Foods and Human Health, Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus, 500 Laureate Way, Kannapolis, NC Abstract Beneficial properties of resveratrol and pterostilbene, a dimethyl ether analog […]

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Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury

Wenliang Zhang, Wei Zhong, Qian Sun, Xinguo Sun & Zhanxiang Zhou (2018). Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury. Scientific Reports 8, 408. Author Affiliations Center for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, NC, 28081, USA Department of Nutrition, University of North Carolina at […]

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Targeting the gut barrier for the treatment of alcoholic liver disease

Zhanxiang Zhou, Wei Zhong (2017). Targeting the gut barrier for the treatment of alcoholic liver disease. Liver Research. Author Affiliations Center for Translational Biomedical Research, School of Health and Human Sciences, University of North Carolina at Greensboro, Kannapolis, NC, USA Department of Nutrition, School of Health and Human Sciences, University of North Carolina at Greensboro, […]

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Contribution of Dietary Supplements to Nutritional Adequacy by Socioeconomic Subgroups in Adults of the United States

Jeffrey B. Blumberg, Balz Frei, Victor L. Fulgoni III, Connie M. Weaver and Steven H. Zeisel (2018). Contribution of Dietary Supplements to Nutritional Adequacy by Socioeconomic Subgroups in Adults of the United States. Nutrients, 10(1), 4. Author Affiliations Antioxidants Research Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, and the Friedman School of […]

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Comparative genetic mapping reveals synteny and collinearity between the American cranberry and diploid blueberry genomes

Brandon Schlautman, Luis Diaz-Garcia, Giovanny Covarrubias-Pazaran, Nathan Schlautman, Nicholi Vorsa, James Polashock, Elizabeth L. Ogden, Allan Brown, Ying-Chen Lin, Nahla Bassil, Emily J. Buck, Claudia Wiedow, Susan McCallum, Julie Graham, Massimo Iorizzo, Lisa J. Rowland, Juan Zalapa (2018). Comparative genetic mapping reveals synteny and collinearity between the American cranberry and diploid blueberry genomes. Molecular Breeding, […]

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Role of NRF2 in Preventing Oxidative Stress Induced Chloride Current Alteration in Human Lung Cells

Canella R, Benedusi M, Martini M, Cervellati F, Cavicchio C, Valacchi G (2017). Role of NRF2 in Preventing Oxidative Stress Induced Chloride Current Alteration in Human Lung Cells. Journal of Cellular Physiology. Author Affiliations Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy. NC State University, Plants for Human Health Institute, Animal Science […]

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Online 2D-LC-MS/MS Platform for Analysis of Glycated Proteome

Lina Zhang, Chih-Wei Liu, and Qibin Zhang (2017). Online 2D-LC-MS/MS Platform for Analysis of Glycated Proteome. Analytical Chemistry. Author Affiliations Center for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, North Carolina 28081, United States Department of Chemistry & Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina […]

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A “Shocking” New Code Status

Anant Mandawat, Aditya Mandawat, Gregory Curfman, L. Kristin Newby (2017). A “Shocking” New Code Status. American Heart Journal. Author Affiliations: Division of Cardiology, Duke University Medical Center, Durham, NC Harvard Medical School, Boston, MA Article outline: There are approximately 200,000 in-hospital cardiac arrests in the United States each year for which resuscitation is attempted.1 Although […]

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Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups

Jeffrey B. Blumberg, Balz Frei, Victor L. Fulgoni, Connie M. Weaver and Steven H. Zeisel (2017). Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups. Nutrients 9(12). Author Affiliations: Antioxidants Research Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, and the Friedman School of Nutrition Science and Policy, Tufts University, […]

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Novel Artificial Tears Containing Cross-Linked Hyaluronic Acid: An In Vitro Re-Epithelialization Study

Arianna Fallacara, Silvia Vertuani, Giacomo Panozzo, Alessandra Pecorelli, Giuseppe Valacchi and Stefano Manfredini (2017). Novel Artificial Tears Containing Cross-Linked Hyaluronic Acid: An In Vitro Re-Epithelialization Study. Molecules 22(12). Author Affiliations: Department of Life Sciences and Biotechnology, Master Course in Cosmetic Science and Technology (COSMAST), University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy Ophthalmology […]

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(QuillConII) Application of DNA flow cytometry to aid species delimitation in Isoetes

Jay F. Bolin, Carmony L Hartwig, Peter Schafran, and Slavko Komarnystsky (2017) (QuillConII) Application of DNA flow cytometry to aid species delimitation in Isoetes. Castanea. Author Affiliations: Catawba Dept of Biology Catawba College Dept. of Biology. Old Dominion University Dept. of Biological Sciences North Carolina State University Plants for Human Health Institute Abstract: The genus […]

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Complexation with phenolic acids affect rheological properties and digestibility of potato starch and maize amylopectin

Min Li, Chris Pernell, Mario G. Ferruzzi (2017). Complexation with phenolic acids affect rheological properties and digestibility of potato starch and maize amylopectin. Food Hydrocolloids. Author Affiliations Plants for Human Health Institute, North Carolina State University, Kannapolis, NC 28081, USA Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC 27606, USA […]

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Acute intravenous exposure to silver nanoparticles during pregnancy induces particle size and vehicle dependent changes in vascular tissue contractility in Sprague Dawley rats

A.K. Vidanapathirana, L.C. Thompson, M. Herco, J. Odom, S.J. Sumner, T.R. Fennell, J.M. Brown, C.J.Wingard (2017). Acute intravenous exposure to silver nanoparticles during pregnancy induces particle size and vehicle dependent changes in vascular tissue contractility in Sprague Dawley rats. Reproductive Toxicology 76, 10-22. Author Affiliations Department of Physiology, Brody School of Medicine, East Carolina University, […]

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Paraoxonase, arylesterase and lactonase activities of paraoxonase-1 (PON1) in obese and severely obese women

Carlo Cervellati, Gloria Bonaccorsi, Alessandro Trentini, Giuseppe Valacchi, Juana M. Sanz, Monica Squerzanti, Manuela Spagnolo, Leo Massari, Ilaria Crivellari, Pantaleo Greco, Roberta Parladori, Angelina Passaro & Giorgio Ricci (2017). Paraoxonase, arylesterase and lactonase activities of paraoxonase-1 (PON1) in obese and severely obese women. Scandinavian Journal of Clinical and Laboratory Investigation. Author Affiliations Department of Biomedical […]

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Lactonase activity and lipoprotein-phospholipase A2 as possible novel serum biomarkers for the differential 2 diagnosis of autism spectrum disorders and Rett syndrome: results from a pilot study

Joussef Hayek, Carlo Cervellati, Ilaria Crivellari, Alessandra Pecorelli, Giuseppe Valacchi (2017). Lactonase activity and lipoprotein-phospholipase A2 as possible novel serum biomarkers for the differential diagnosis of autism spectrum disorders and Rett syndrome: results from a pilot study. Oxidative Medicine and Cellular Longevity. Author Affiliations Child Neuropsychiatry Unit, University General Hospital, Azienda Ospedaliera Universitaria Senese, Viale […]

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Keratinocytes oxidative damage mechanisms related to airbone particle matter exposure

Arianna Romani, Carlo Cervellati, Ximena M. Muresan, Giuseppe Belmonte, Alessandra Pecorelli, Franco Cervellati, Mascia Benedusi, Pablo Evelson, G. Valacchi (2017). Keratinocytes oxidative damage mechanisms related to airbone particle matter exposure. Mechanisms of Ageing and Development. Author Affiliations Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy Department of Biomedical and Specialist Surgical Sciences, […]

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A Microbiomic Analysis in African Americans with Colonic Lesions Reveals Streptococcus sp.VT162 as a Marker of Neoplastic Transformation

Hassan Brim, Shibu Yooseph, Edward Lee, Zaki Sherif, Muneer Abbas, Adeyinka O. Laiyemo, Sudhir Varma, Manolito Torralba, Scot E. Dowd, Karen E. Nelson, Wimal Pathmasiri, Susan Sumner, Willem de Vos, Qiaoyi Liang, Jun Yu, Erwin Zoetendal and Hassan Ashktorab (2017). A Microbiomic Analysis in African Americans with Colonic Lesions Reveals Streptococcus sp.VT162 as a Marker […]

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Modulation of cutaneous scavenger receptor B1 levels by exogenous stressors impairs “in vitro” wound closure

Ximena Maria Muresan, Claudia Sticozzi, Giuseppe Belmonte, Vinno Savelli, Pablo Evelson, Giuseppe Valacchi (2017). Modulation of cutaneous scavenger receptor B1 levels by exogenous stressors impairs “in vitro” wound closure. Mechanisms of Ageing and Development. Author Affiliations Dept. of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy Plants for Human Health Institute, Animal Sciences Dept., […]

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Effect of Four Weeks Ingestion of Tomato-Based Carotenoids on Exercise-Induced Inflammation, Muscle Damage, and Oxidative Stress in Endurance Runners

David C. Nieman, Courtney L. Capps, Christopher R. Capps, Zack L. Shue, Jennifer E. McBride (2017). Effect of Four Weeks Ingestion of Tomato-Based Carotenoids on Exercise-Induced Inflammation, Muscle Damage, and Oxidative Stress in Endurance Runners. The International Journal of Sport Nutrition and Exercise Metabolism, pp. 1-26. Author Affiliations Appalachian State University, Human Performance Lab, North […]

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Anthocyanin Pigments in Redbud (Cercis spp) Flowers

Penelope Perkins Veazie, Guoying Ma and Dennis Werner (2017). Anthocyanin Pigments in Redbud (Cercis spp) Flowers. The Scientific Pages of Horticulture, 1(1):13-18. Author Affiliations Department of Horticultural Science, Plants for Human Health Institute, North Carolina State University, USA Abstract Redbud (Cercis spp.) is used as a spring flowering ornamental tree and is found wild in […]

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Similarity between soybean and Arabidopsis seed methylomes and loss of non-CG methylation does not affect seed development

Jer-Young Lin, Brandon H. Le, Min Chen, Kelli F. Henry, Jungim Hur, Tzung-Fu Hsieh, Pao-Yang Chen, Julie M. Pelletier, Matteo Pellegrini, Robert L. Fischer, John J. Harada, and Robert B. Goldberga (2017). Similarity between soybean and Arabidopsis seed methylomes and loss of non-CG methylation does not affect seed development. Proceedings of the National Academy of […]

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Randomized trial comparing group size of periodic in-person sessions in a remotely delivered weight loss intervention

Deborah F. Tate, Carmina G. Valle, Melissa M. Crane, Brooke T. Nezami, Carmen D. Samuel-Hodge, Karen E. Hatley, Molly Diamond and Kristen Polzien (2017). Randomized trial comparing group size of periodic in-person sessions in a remotely delivered weight loss intervention. International Journal of Behavioral Nutrition, 14:144. Author Affiliations Department of Health Behavior, Department of Nutrition, […]

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Establishing Standards on Colors from Natural Sources

James E. Simon, Eric A. Decker, Mario G. Ferruzzi, M. Monica Giusti, Carla D. Mejia, Mark Goldschmidt, Stephen T. Talcott (2017). Establishing Standards on Colors from Natural Sources. Journal of Food Science. Author Affiliations New Use Agriculture and Natural Plant Products Program, Dept. of Plant Biology, Rutgers Univ., New Brunswick, NJ 08901, U.S.A. Dept. of […]

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Hepatotoxicity: Treatment, causes and applications of medicinal plants as therapeutic agents

Meagan Thompson, Yogini Jaiswal, Ilya Wang, Leonard Williams (2017). Hepatotoxicity: Treatment, causes and applications of medicinal plants as therapeutic agents. The Journal of Phytopharmacology, 6(3): 186-193. Author Affiliations Center for Excellence in Post-Harvest Technologies, The North Carolina Research Campus, 500 Laureate Way, Kannapolis, NC 28081, USA Appalachian State University, 287 Rivers Street, Boone, NC 28608, […]

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Influence of 2-Weeks Ingestion of High Chlorogenic Acid Coffee On Mood State, Performance, and Post-Exercise Inflammation and Oxidative Stress: A Randomized, Placebo Controlled Trial

David C. Nieman, Courtney L. Goodman, Christopher R. Capps, Zack L. Shue, Robert Arnot (2017). Influence of 2-Weeks Ingestion of High Chlorogenic Acid Coffee On Mood State, Performance, and Post-Exercise Inflammation and Oxidative Stress: A Randomized, Placebo Controlled Trial. Sport Nutrition and Exercise Metabolism, pp. 1-26. Author Affiliations: Appalachian State University, Human Performance Lab, North […]

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Isobaric Labeling-Based LC-MS/MS Strategy for Comprehensive Profiling of Human Pancreatic Tissue Proteome

Chih-Wei Liu and Qibin Zhang (2017). Isobaric Labeling-Based LC-MS/MS Strategy for Comprehensive Profiling of Human Pancreatic Tissue Proteome. Methods in Molecular Biology. Author Affiliations Center for Translational Biomedical Research University of North Carolina at Greensboro Kannapolis USA Department of Chemistry and Biochemistry University of North Carolina at Greensboro Greensboro USA Abstract The pancreas is an […]

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Interindividual Variability in Metabolism of [6]-Shogaol by Gut Microbiota

Pei Wang, Ronghui Wang, Yingdong Zhu, and Shengmin Sang (2017). Interindividual Variability in Metabolism of [6]-Shogaol by Gut Microbiota. Journal of Agricultural and Food Chemistry. Abstract [6]-Shogaol (6S), one of the major bioactive components in dry ginger, is attracting considerable attention because of its wide spectrum of biological activities, but its metabolic fate is still […]

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Temporal expression profiling of plasma proteins reveals oxidative stress in early stages of Type 1 Diabetes progression

Chih-Wei Liu, Lisa Bramer, Bobbie-Jo Webb-Robertson, Kathleen Waugh, Marian J. Rewers, Qibin Zhang (2017). Temporal expression profiling of plasma proteins reveals oxidative stress in early stages of Type 1 Diabetes progression. Journal of Proteomics. Author Affiliations Center for Translational Biomedical Research, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis, NC, United States […]

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Maternal Iron Nutriture as a Critical Modulator of FASD Risk in Alcohol-Exposed Pregnancies

Kaylee K. Helfrich, Nipun Saini, Pamela J. Kling, Susan M. Smith (2017). Maternal Iron Nutriture as a Critical Modulator of FASD Risk in Alcohol-Exposed Pregnancies. Biochemistry and Cell Biology. Abstract Alcohol consumption during pregnancy places the fetus at risk for permanent physical, cognitive, and behavioral impairments, collectively termed fetal alcohol spectrum disorders (FASD). However, prenatal […]

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The Avian Embryo as a Model for Fetal Alcohol Spectrum Disorders

Susan M. Smith, George R. Flentke (2017). The Avian Embryo as a Model for Fetal Alcohol Spectrum Disorders. Biochemistry and Cell Biology. Abstract Prenatal alcohol exposure (PAE) remains a leading preventable cause of structural birth defects and permanent neurodevelopmental disability. The chick (Gallus gallus domesticus) is a powerful embryological research model and was possibly the […]

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Dietary Copper-Fructose Interactions Alter Gut Microbial Activity in Male Rats

Ming Song, Xiaohong Li, Xiang Zhang, Hongxue Shi, Miriam B. Vos, Xiaoli Wei, Yuhua Wang, Hong Gao, Eric C Rouchka, Xinmin Yin, Zhanxiang Zhou, Russell A. Prough, Matthew C. Cave, Craig J. McClain (2017). Dietary Copper-Fructose Interactions Alter Gut Microbial Activity in Male Rats. American Journal of Physiology – Gastrointestinal and Liver Physiology. Author Affiliation […]

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Metformin as an anti-cancer agent: actions and mechanisms targeting cancer stem cells

Nipun Saini and Xiaohe Yang (2017). Metformin as an anti-cancer agent: actions and mechanisms targeting cancer stem cells. Acta Biochimica et Biophysica Sinica. Author Affiliations Julius L. Chambers Biomedical/Biotechnology Research Institute, Department of Biological and Biomedical Sciences, North Carolina Central University, North Carolina Research Campus, Kannapolis, NC 28081, USA Abstract Metformin, a first line medication […]

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Metformin as an anti-cancer agent: actions and mechanisms targeting cancer stem cells

Nipun Saini and Xiaohe Yang (2017). Metformin as an anti-cancer agent: actions and mechanisms targeting cancer stem cells. Acta Biochimica et Biophysica Sinica. Author Affiliations: Julius L. Chambers Biomedical/Biotechnology Research Institute, Department of Biological and Biomedical Sciences, North Carolina Central University, North Carolina Research Campus, Kannapolis, NC 28081, USA Abstract: Metformin, a first line medication […]

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A disulfide bond A-like oxidoreductase is a strong candidate gene for self-incompatibility in apricot (Prunus armeniaca) pollen

Juan Vicente Muñoz-Sanz, Elena Zuriaga, María L. Badenes, and Carlos Romero (2017). A disulfide bond A-like oxidoreductase is a strong candidate gene for self-incompatibility in apricot (Prunus armeniaca) pollen. Journal of Experimental Botany. Author Affiliations Fruit Tree Breeding Department. Instituto Valenciano de Investigaciones Agrarias (IVIA). CV-315, Km. 10,7. 46113 Moncada (Valencia), Spain Instituto de Biología Molecular y Celular de Plantas […]

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Salt tolerance response revealed by RNA-Seq in a diploid halophytic wild relative of sweet potato.

Luo Y, Reid R, Freese D, Li C, Watkins J, Shi H, Zhang H, Loraine A, Song BH (2017). Salt tolerance response revealed by RNA-Seq in a diploid halophytic wild relative of sweet potato. Scientific Reports 7(1):9624. Author Affiliations Department of Biological Sciences, University of North Carolina at Charlotte, Charlotte, NC, 28223, USA. Key Laboratory […]

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Risk for Alcohol-Exposed Pregnancies Among Women at Drinking Venues in Cape Town, South Africa

Melissa H. Watt, Brandon A. Knettel, Karmel W. Choi, Elizabeth T. Knippler, Philip A. May, & Soraya Seedat (2017). Risk for Alcohol-Exposed Pregnancies Among Women at Drinking Venues in Cape Town, South Africa. Journal of Studies on Alcohol and Drugs, 78(5), 795–800. Author Affiliations Duke Global Health Institute, Duke University, Durham, North Carolina Department of […]

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Resveratrol from diet to topical usage

Veronica Sanda Chedea, Simona Ioana Vicas, Claudia Sticozzi, Federica Pessina, Maria Frosini, Emanuela Maioli and Giuseppe Valacchi (2017). Resveratrol from diet to topical usage. Food & Function. Abstract The stilbene derivative Resveratrol (3,5,4’-trihydroxy-stilbene; RESV) has become the subject of interest of many researchers and pharmaceutical industries due to its well-claimed biological beneficial activities. Although earlier […]

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Preparing Fellows for Precision Cardiology: Are We Ready?

Muthiah Vaduganathan, Geoffrey S. Ginsburg, Arman Qamar and Krishna Aragam (2017). Preparing Fellows for Precision Cardiology: Are We Ready? Journal of the American College of Cardiology, 70(13). Author Affiliations Brigham and Women’s Hospital Heart & Vascular Center and Harvard Medical School, Boston, Massachusetts Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts […]

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Perinatal western-type diet and associated gestational weight gain alter postpartum maternal mood

Jessica L. Bolton, Melanie G. Wiley, Bailey Ryan, Samantha Truong, Melva Strait, Dana Creighton Baker, Nancy Y. Yang, Olga Ilkayeva, Thomas M. O’Connell, Shelley W. Wroth, Cristina L. Sánchez, Geeta Swamy, Christopher Newgard, Cynthia Kuhn, Staci D. Bilbo, Leigh Ann Simmons (2017). Perinatal western-type diet and associated gestational weight gain alter postpartum maternal mood. Brain […]

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Recent urbanization in China is correlated with a Westernized microbiome encoding increased virulence and antibiotic resistance genes

Kathryn Winglee, Annie Green Howard, Wei Sha, Raad Z. Gharaibeh, Jiawu Liu, Donghui Jin, Anthony A. Fodor and Penny Gordon-Larsen (2017). Recent urbanization in China is correlated with a Westernized microbiome encoding increased virulence and antibiotic resistance genes. Microbiome 5:121. Author Affiliations Department of Bioinformatics and Genomics, University of North Carolina at Charlotte Department of […]

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LinkageMapView – Rendering High Resolution Linkage and QTL Maps

Lisa A. Ouellette, Robert W. Reid, Steven G. Blanchard Jr., and Cory R. Brouwer (2017) LinkageMapView – Rendering High Resolution Linkage and QTL Maps. Bioinformatics. Author Affiliations Department of Bioinformatics and Genomics, University of North Carolina Charlotte, 150 Research Campus Drive, Suite 3333, Kannapolis, NC, USA. Abstract Linkage and quantitative trait loci (QTL) maps are […]

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Failure to Launch: Targeting Inflammation in Acute Coronary Syndromes

Jennifer A. Rymer, Kristin Newby (2017). Failure to Launch: Targeting Inflammation in Acute Coronary Syndromes. JACC: Basic to Translational Science 2(4) 484-497. Author Affiliations Division of Cardiology, Department of Medicine, and Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina Abstract The importance of inflammation and inflammatory pathways in atherosclerotic disease and […]

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Circadian clock as possible protective mechanism to pollution induced keratinocytes damage

Mascia Benedusi, Elena Frigato, Mattia Beltramello, Cristiano Bertolucci, Giuseppe Valacchi (2017). Circadian clock as possible protective mechanism to pollution induced keratinocytes damage. Mechanisms of Ageing and Development. Author Affiliations Department of Life Sciences and Biotechnology, Section of Medicinal and Health Products, University of Ferrara, I-44121 Ferrara, Italy NC State University, Plants for Human Health Institute, […]

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Structural Analysis of Unsaturated Glycosphingolipids Using Shotgun Ozone-Induced Dissociation Mass Spectrometry

Rodell C. Barrientos, Ngoc Vu, Qibin Zhang (2017) Structural Analysis of Unsaturated Glycosphingolipids Using Shotgun Ozone-Induced Dissociation Mass Spectrometry. Journal of The American Society for Mass Spectrometry 1-4. Author Affiliations 1.Department of Chemistry and Biochemistry The University of North Carolina at Greensboro Greensboro USA 2.UNCG Center for Translational Biomedical Research Kannapolis USA Abstract Glycosphingolipids are […]

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Short-term greenhouse emission lowering effect of biochars from solid organic municipal wastes

Djaafar Rehrah, Rishipal R. Bansode, Osman Hassan, Mohamed Ahmedna (2017) Short-term greenhouse emission lowering effect of biochars from solid organic municipal wastes. International Journal of Environmental Science and Technology 1-10. Author Affiliations 1.Department of Human Nutrition, College of Health Sciences Qatar University Doha Qatar 2.Center for Excellence in Post-Harvest Technologies, North Carolina Research Campus North […]

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Effect of UV irradiation on aflatoxin reduction: a cytotoxicity evaluation study using human hepatoma cell line

Ankit Patras, Sharath Julakanti, Sudheer Yannam, Rishipal R. Bansode, Mallory Burns, Matthew J. Vergne (2017) Effect of UV irradiation on aflatoxin reduction: a cytotoxicity evaluation study using human hepatoma cell line. Mycotoxin Research 1-8. Author Affiliations 1.Food Biosciences and Technology Program, Department of Agricultural and Environmental Sciences Tennessee State University Nashville USA 2. Center for […]

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Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice.

Zhang W, Zhong W, Sun Q, Sun X, Zhou Z (2017) Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice. Scientific Reports 7(1):8976. Author Affiliations 1. Center for Translational Biomedical Research, University of North Carolina Greensboro, North Carolina Research Campus, Kannapolis, NC, 28081, USA. 2. Center for Translational Biomedical […]

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Metabolomics reveal physiological changes in mayfly larvae ( Neocloeon triangulifer ) at ecological upper thermal limits.

Hsuan Chou, Wimal Pathmasiri, Jocelin Deese-Spruill, Susan Sumner, David B Buchwalter (2017). Metabolomics reveal physiological changes in mayfly larvae ( Neocloeon triangulifer ) at ecological upper thermal limits. Journal of Insect Physiology 101 (107-112). Note: The David H. Murdock Research Institute provided NMR services and analysis for this paper. Author Affiliations Graduate Toxicology Program, Department […]

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Impact of Frequency of Multi-Vitamin/Multi-Mineral Supplement Intake on Nutritional Adequacy and Nutrient Deficiencies in U.S. Adults

Jeffrey B. Blumberg, Balz B. Frei, Victor L. Fulgoni III, Connie M. Weaver and Steven H. Zeisel (2017). Impact of Frequency of Multi-Vitamin/Multi-Mineral Supplement Intake on Nutritional Adequacy and Nutrient Deficiencies in U.S. Adults. Nutrients 9(8) 849. Author Affiliations 1 Antioxidants Research Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging and Friedman School […]

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Heritability and Genetic Variance Components Associated with Citrulline, Arginine, and Lycopene Content in Diverse Watermelon Cultigens

Todd C. Wehner, Rachel P. Naegele, Penelope Perkins-Veazie (2017). Heritability and Genetic Variance Components Associated with Citrulline, Arginine, and Lycopene Content in Diverse Watermelon Cultigens. HortScience 52(7) 936-940. Author Affiliations Department of Horticultural Science, North Carolina State University, Raleigh, NC 27695-7609 USDA, Agricultural Research Service, San Joaquin Valley Agricultural Sciences Center, 9611 S. Riverbend Avenue, […]

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Phenformin inhibits growth and epithelial-mesenchymal transition of ErbB2-overexpressing breast cancer cells through targeting the IGF1R pathway.

Guo Z, Zhao M, Howard EW, Zhao Q, Parris AB, Ma Z, Yang X (2017). Phenformin inhibits growth and epithelial-mesenchymal transition of ErbB2-overexpressing breast cancer cells through targeting the IGF1R pathway. Oncotarget. Author Affiliations Julius L. Chambers Biomedical/Biotechnology Research Institute, Department of Biological and Biomedical Sciences, North Carolina Central University, Kannapolis, North Carolina, USA. Abstract […]

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A proposed approach to accelerate evidence generation for genomic-based technologies in the context of a learning health system.

Lu CY 1, Williams MS 2, Ginsburg GS 3, Toh S 1, Brown JS 1, Khoury MJ 4 (2017). A proposed approach to accelerate evidence generation for genomic-based technologies in the context of a learning health system. Genetics in Medicine. Author Affiliations 1. Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care […]

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GPR40 partial agonist MK-2305 lower fasting glucose in the Goto Kakizaki rat via suppression of endogenous glucose production.

Miller, C.; Pachanski, M.J.; Kirkland, M.E.; Kosinski, D.T.; Mane, J.; Bunzel, M.; Cao, J.; Souza, S.; Thomas-Fowlkes, B.; Di Salvo, J.; Weinglass, A.G.; Li, X.; Myers, R.W.; Knagge, K.; Carrington, P.E.; Hagmann, W.K.; Trujillo, M.E.  2017.  GPR40 partial agonist MK-2305 lower fasting glucose in the Goto Kakizaki rat via suppression of endogenous glucose production.  PLos […]

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In-Hospital Cardiac Arrest: Complex Clinical Challenges in Need of Unique Solutions

Angela Lowenstern, MD, Anant Mandawat, MD, L. Kristin Newby, MD, MHS (2017). In-Hospital Cardiac Arrest: Complex Clinical Challenges in Need of Unique Solutions. American Heart Journal. Author Affiliations: Division of Cardiology, Department of Medicine (AL, AM, LKN) and the Duke Clinical Research Institute (AL, LKN), Duke University Medical Center, Durham, NC Abstract: It is estimated […]

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Phytoecdysteroid-enriched quinoa seed leachate enhances healthspan and mitochondrial metabolism in Caenorhabditis elegans

Brittany L. Grafa, Shaunak Kamat, Kuan Yu Cheong, Slavko Komarnytsky, Monica Driscoll, Rong Di (2017). Phytoecdysteroid-enriched quinoa seed leachate enhances healthspan and mitochondrial metabolism in Caenorhabditis elegans. Journal of Functional Foods 37(1-7). Author Affiliations a. Department of Plant Biology and Pathology, Rutgers University, 59 Dudley Rd, New Brunswick, NJ 08901, USA b. Department of Molecular […]

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Reduced brain volume and impaired memory in betaine homocysteine S-methyltransferase knockout mice

Emily A.K. Prieur , Eneda Pjetri, Steven H. Zeisel, Nafisa M Jadavji (2017). Reduced brain volume and impaired memory in betaine homocysteine S-methyltransferase knockout mice. Applied Physiology, Nutrition, and Metabolism. Abstract Using a mouse model, this study examined the impact of lack of betaine homocysteine S-methyltransferase (BHMT) on neurological function. Bhmt-/- mice maintained on a […]

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Muskmelon Fruit Quality in Response to Postharvest Essential Oil and Whey Protein Sprays

Chen Jiang, Penelope Perkins-Veazie, Guoying Ma, and Christopher Gunter (2017). Muskmelon Fruit Quality in Response to Postharvest Essential Oil and Whey Protein Sprays. HortScience 52(6) 887-891. Author Affiliations Department of Horticultural Science, North Carolina State University, P.O. Box 7609, 2721 Founders Drive, Raleigh, NC 27695 Department of Horticultural Science, North Carolina State University, P.O. Box […]

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Quercetin and Green Tea Extract Supplementation Downregulates Genes Related to Tissue Inflammatory Responses to a 12-Week High Fat-Diet in Mice

Lynn Cialdella-Kam, Sujoy Ghosh, Mary Pat Meaney, Amy M. Knab, R. Andrew Shanely and David C. Nieman (2017). Quercetin and Green Tea Extract Supplementation Downregulates Genes Related to Tissue Inflammatory Responses to a 12-Week High Fat-Diet in Mice. Nutrients 9(7) 773. Author Affiliations 1 Department of Nutrition, School of Medicine—WG 48, Case Western Reserve University, […]

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Cross-Community Collaboration in Cabarrus County

Mardovich, Sarah (2017). Cross-Community Collaboration in Cabarrus County. North Carolina Medical Journal 78(4) 251-254. Author Affiliation: Cabarrus Health Alliance Abstract: Collaborative action is a part of Cabarrus Health Alliance’s mission statement. This commentary highlights several community-based initiatives that the Alliance has used to contribute to the Healthiest Cities & Counties Challenge, and demonstrates the importance […]

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Guide for Current Nutrigenetic, Nutrigenomic, and Nutriepigenetic Approaches for Precision Nutrition Involving the Prevention and Management of Chronic Diseases Associated with Obesity

Ramos-Lopez, O.; Milagro F.I.; Allayee H.; Chmurzynska A.; Choi M.S.; Curi R.; De Caterina R.; Ferguson L.R.; Goni L.; Kang J.X.; Kohlmeier M.; Marti A.; Moreno L.A.; Pérusse L.; Prasad C.; Qi L.; Reifen R.; Riezu-Boj J.I.; San-Cristobal R.; Santos J.L.; Martínez J.A (2017). Guide for Current Nutrigenetic, Nutrigenomic, and Nutriepigenetic Approaches for Precision Nutrition […]

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Nanostructured lipid systems modified with waste material of propolis for wound healing: Design, in vitro and in vivo evaluation

Hélen Cássia Rosseto, Lucas de Alcântara Sica de Toledo, Lizziane Maria Belloto de Francisco, Elisabetta Esposito, Yunsook Lim, Giuseppe Valacchi, Rita Cortesi, Marcos Luciano Bruschi (2017). Nanostructured lipid systems modified with waste material of propolis for wound healing: Design, in vitro and in vivo evaluation. Colloids and Surfaces B: Biointerfaces, 158(441-452). Author Affiliations: a. Postgraduate […]

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Potassium ascorbate with ribose – promising therapeutic approach for melanoma treatment

Carlotta Cavicchio, Mascia Benedusi, Erika Pambianchi, Alessandra Pecorelli, Franco Cervellati, Vinno Savelli, Duccio Calamandrei, Emilia Maellaro, Giorgio Rispoli, Emanuela Maioli, Giuseppe Valacchi (2017). Potassium ascorbate with ribose – promising therapeutic approach for melanoma treatment. Oxidative Medicine and Cellular Longevity. Author Affiliations 1. Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy; 2. Plants […]

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Ganetespib induces G2/M cell cycle arrest and apoptosis in gastric cancer cells through targeting of receptor tyrosine kinase signaling

Harry Lee, Nipun Saini, Amanda B. Parris, Ming Zhao, Xiaohe Yang (2017). Ganetespib induces G2/M cell cycle arrest and apoptosis in gastric cancer cells through targeting of receptor tyrosine kinase signaling. International Journal of Oncology. Author Affiliations Julius L. Chambers Biomedical/Biotechnology Research Institute, Department of Biological and Biomedical Sciences, North Carolina Central University, Kannapolis, NC […]

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Cytokinin induces genome-wide binding of the type-B response regulator ARR10 to regulate growth and development in Arabidopsis

Yan O. Zubo, Ivory Clabaugh Blakley, Maria V. Yamburenko, Jennifer M. Worthen, Ian H. Street, José M. Franco-Zorrilla, Wenjing Zhang, Kristine Hill, Tracy Raines, Roberto Solano, Joseph J. Kieber, Ann E. Loraine, and G. Eric Schaller (2017). Cytokinin induces genome-wide binding of the type-B response regulator ARR10 to regulate growth and development in Arabidopsis. Proceedings […]

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Multiple roles of RARRES1 in prostate cancer: Autophagy induction and angiogenesis inhibition

Arpita Roy, Malathi Ramalinga, Okjin J. Kim, Juliet Chijioke, Solomon Lynch, Stephen Byers, Deepak Kumar (2017). Multiple roles of RARRES1 in prostate cancer: Autophagy induction and angiogenesis inhibition. PLOS One. Author Affiliations Cancer Research Laboratory, University of the District of Columbia, Washington, DC, United States of America Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, […]

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Patulin degradation and cytotoxicity evaluation of UV irradiated apple juice using human peripheral blood mononuclear cells

Sharath Chandra, Ankit Patras, Bharat Pokharel, Rishipal R. Bansode, Afroza Begum, Michael Sasges (2017). Patulin degradation and cytotoxicity evaluation of UV irradiated apple juice using human peripheral blood mononuclear cells. Journal of Food Process Engineering. Author Affiliations Department of Agricultural and Environmental Sciences, Tennessee State University, Nashville, Tennessee Center for Excellence in Post-Harvest Technologies, North […]

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Influence of Ingesting a Flavonoid-Rich Supplement on the Metabolome and Concentration of Urine Phenolics in Overweight/Obese Women

David C. Nieman, Sivapriya Ramamoorthy, Colin D. Kay, Courtney L. Goodman, Christopher R. Capps, Zack L. Shue, Nicole Heyl, Mary H. Grace, and Mary A. Lila (2017). Influence of Ingesting a Flavonoid-Rich Supplement on the Metabolome and Concentration of Urine Phenolics in Overweight/Obese Women. Journal of Proteome Research. Author Affiliations Human Performance Lab, Appalachian State […]

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Tissue based metabolite profiling and qualitative comparison of two species of Achyranthes roots by use of UHPLC-QTOF MS and laser micro dissection

Yogini Jaiswal, Zhitao Liang, Alan Ho, Hubiao Chen, Leonard Williams, Zhongzhen Zhao (2017). Tissue based metabolite profiling and qualitative comparison of two species of Achyranthes roots by use of UHPLC-QTOF MS and laser micro dissection. Journal of Pharmaceutical Analysis. Author Affiliations a Center for Excellence in Post-Harvest Technologies, The North Carolina Research Campus, 500 Laureate […]

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Quantitative Trait Loci Mapping of Agronomic and Yield Traits in Two Grain Sorghum Biparental Families

Richard E. Boyles, Brian K. Pfieffer, Elizabeth A. Cooper, Kelsey J. Zielinski, Matthew T. Myers, William L. Rooney and Stephen Kresovich (2017). Quantitative Trait Loci Mapping of Agronomic and Yield Traits in Two Grain Sorghum Biparental Families. Crop Science. Author Affiliations a Advanced Plant Technology Program, Clemson Univ., Clemson, South Carolina 29634 b Pee Dee […]

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Virucidal Activity of Fogged Chlorine Dioxide- and Hydrogen Peroxide-Based Disinfectants against Human Norovirus and Its Surrogate, Feline Calicivirus, on Hard-to-Reach Surfaces

Naim Montazeri, Clyde Manuel, Eric Moorman, Janak R. Khatiwada, Leonard L. Williams and Lee-Ann Jaykus (2017). Virucidal Activity of Fogged Chlorine Dioxide- and Hydrogen Peroxide-Based Disinfectants against Human Norovirus and Its Surrogate, Feline Calicivirus, on Hard-to-Reach Surfaces. Frontiers in Microbiology. Author Affiliations 1 Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, […]

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First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents

Simone Brogi, Anna Ramunno, 1, Lida Savi, Giulia Chemi, Gloria Alfano, Alessandra Pecorelli, Erika Pambianchi, Paola Galatello, Giulia Compagnoni, Federico Focher, Giuseppe Biamonti, Giuseppe Valacchi, Stefania Butini, Sandra Gemmaa, Giuseppe Campiania, Margherita Brindisi (2017). First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents. European Journal of Medicinal Chemistry. Author Affiliatons a […]

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Who is most affected by prenatal alcohol exposure: Boys or girls?

Philip A. May, Barbara Tabachnick, Julie M. Hasken, Anna-Susan Marais, Marlene M. de Vries, Ronel Barnard, Belinda Joubert, Marise Cloete, Isobel Botha, Wendy O. Kalberg, David Buckley, Zachary R. Burroughs, Heidre Bezuidenhout, Luther K. Robinson, Melanie A. Manning, Colleen M. Adnams, Soraya Seedat, Charles D.H. Parry, H. Eugene Hoyme (2017). Who is most affected by […]

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Satisfying America’s Fruit Gap: Summary of an Expert Roundtable on the Role of 100% Fruit Juice

Carol Byrd-Bredbenner, Mario G. Ferruzzi, Victor L. Fulgoni III, Robert Murray, Elizabeth Pivonka, Taylor C. Wallace (2017). Satisfying America’s Fruit Gap: Summary of an Expert Roundtable on the Role of 100% Fruit Juice. Journal of Food Science. Author Affiliations Dept. of Nutritional Sciences, Rutgers Univ., New Brunswick, N.J., U.S.A Dept. Food, Bioprocessing and Nutrition, North […]

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Deletion of one allele of Mthfd1 (methylenetetrahydrofolate dehydrogenase 1) impairs learning in mice

Eneda Pjetria, Steven H. Zeisel (2017). Deletion of one allele of Mthfd1 (methylenetetrahydrofolate dehydrogenase 1) impairs learning in mice. Behavioural Brain Research 332(71-74). Author Affiliations a Nutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, NC 28081, United States b Department of Nutrition, Gillings Global School of Public Health, University of North Carolina […]

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Pathview Web: user friendly pathway visualization and data integration

Luo W, Pant G, Bhavnasi YK, Blanchard SG Jr, Brouwer C. Pathview Web: user friendly pathway visualization and data integration. Nucleic Acids Res. Abstract Pathway analysis is widely used in omics studies. Pathway-based data integration and visualization is a critical component of the analysis. To address this need, we recently developed a novel R package called Pathview. Pathview maps, […]

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GPR40 partial agonist MK-2305 lower fasting glucose in the Goto Kakizaki rat via suppression of endogenous glucose production

Corin Miller , Michele J. Pachanski , Melissa E. Kirkland, Daniel T. Kosinski, Joel Mane, Michelle Bunzel, Jin Cao, Sarah Souza, Brande Thomas-Fowlkes, Jerry Di Salvo, Adam B. Weinglass, Xiaoyan Li, Robert W. Myers, Kevin Knagge, Paul E. Carrington, William K. Hagmann, Maria E. Trujillo (2017). GPR40 partial agonist MK-2305 lower fasting glucose in the […]

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Astronaut ophthalmic syndrome

Sara R. Zwart*, Charles R. Gibson†, Jesse F. Gregory‡, Thomas H. Mader§,1, Patrick J. Stover¶, Steven H. Zeisel‖ and Scott M. Smith (2017). Astronaut ophthalmic syndrome. The FASEB Journal. Author Affiliations *Department of Preventive Medicine and Community Health, University of Texas Medical Branch, Galveston, Texas, USA; †Coastal Eye Associates, Webster, Texas, USA; ‡Food Science and […]

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Different phenolic compounds selectively slow down the hydrolysis rates of sucrose and isomaltose by mammalian mucosal α-glucosidases

Jongbin Lim 1, Mario G. Ferruzzi 2 and Bruce R. Hamaker 1 (2017). Different phenolic compounds selectively slow down the hydrolysis rates of sucrose and isomaltose by mammalian mucosal α-glucosidases. The FASEB Journal 31(1). Author Affiliations 1Purdue University, West Lafayette, IN 2North Carolina State University, Kannapolis, NC Abstract The mucosal α-glucosidases are major enzymes which […]

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Challenges and strategies for implementing genomic services in diverse settings: experiences from the Implementing GeNomics In pracTicE (IGNITE) network

Nina R. Sperber, Janet S. Carpenter, Larisa H. Cavallari, Laura J. Damschroder, Rhonda M. Cooper-DeHoff, Joshua C. Denny, Geoffrey S. Ginsburg, Yue Guan, Carol R. Horowitz, Kenneth D. Levy, Mia A. Levy, Ebony B. Madden, Michael E. Matheny, Toni I. Pollin, Victoria M. Pratt, Marc Rosenman, Corrine I. Voils, Kristen W. Weitzel, Russell A. Wilke, […]

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Identification and Characterization of a Class of MALAT1-like Genomic Loci

Bin Zhang, Yuntao S. Mao, Sarah D. Diermeier, Irina V. Novikova, Eric P. Nawrocki, Tom A. Jones, Zsolt Lazar, Chang-Shung Tung, Weijun Luo, Sean R. Eddy (2017). Identification and Characterization of a Class of MALAT1-like Genomic Loci. Cell Reports 19(8). Author Affiliations 1 Cold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, NY 11724, […]

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Protein-polyphenol particles for delivering structural and health functionality

E. Allen Foegeding, Nathalie Plundrich, Margaret Schneider, Caroline Campbell, Mary Ann Lila (2017). Protein-polyphenol particles for delivering structural and health functionality. Food Hydrocolloids. Author Affiliations 1 Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, North Carolina, USA 2 Plants for Human Health Institute, North Carolina State University at the North Carolina […]

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Bridging Research, Education and Practice across disciplines: Need for Nutrition Education/Innovation Programme (NNEdPro)

Shivani Bhat 1, Martin Kohlmeier 1,2 and Sumantra Ray 1 (2017). Bridging Research, Education and Practice across disciplines: Need for Nutrition Education/Innovation Programme (NNEdPro). The FASEB Journal 31(1). Author Affiliations 1. NNEdPro Global Centre for Nutrition and Health, Cambridge, United Kingdom 2. Nutrition in Medicine, UNC Chapel Hill, University of North Carolina, Chapel Hill, NC […]

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Linking Nutrition and Molecular Biology Using Data Mining and Graph Theory

Richard Linchangco, Jeremy J Jay and Cory Brouwer (2017). Linking Nutrition and Molecular Biology Using Data Mining and Graph Theory. The FASEB Journal 31(1). Author Affiliations Bioinformatics and Genomics, University of North Carolina at Charlotte, Charlotte, NC Abstract Cardiovascular disease, cancer, and diabetes are among the leading causes of death in the United States. Factors […]

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Replication of High Fetal Alcohol Spectrum Disorders Prevalence Rates, Child Characteristics, and Maternal Risk Factors in a Second Sample of Rural Communities in South Africa

Philip A. May 1,2,3,* , Marlene M. De Vries 2, Anna-Susan Marais 2, Wendy O. Kalberg 3, David Buckley 3, Colleen M. Adnams 4, Julie M. Hasken 1 et al (2017). Replication of High Fetal Alcohol Spectrum Disorders Prevalence Rates, Child Characteristics, and Maternal Risk Factors in a Second Sample of Rural Communities in South […]

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Protein-bound polyphenols create “ghost” band artifacts during chemiluminescence-based antigen detection

Nathalie Plundrich, Mary Ann Lila, Edward Foegeding, Scot Laster (2017). Protein-bound polyphenols create “ghost” band artifacts during chemiluminescence-based antigen detection. F1000 Research 6(254). Author Affiliations Plants for Human Health Institute , North Carolina Research Campus, North Carolina State University Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, North Carolina, USA Department of Biological Sciences, North Carolina State University, North Carolina, USA Abstract Antigen detection during Western blotting commonly utilizes a horseradish peroxidase-coupled secondary antibody and enhanced chemiluminescent substrate. We utilized this technique to examine the impact of green tea-derived polyphenols on the binding of egg white protein-specific IgE antibodies from allergic human plasma to their cognate antigens. Our experiments unexpectedly showed that green tea-derived polyphenols, when stably complexed with egg white proteins, caused hyperactivation of horseradish peroxidase resulting in the appearance of white “ghost” bands. This study suggests that caution should be taken when evaluating polyphenol-bound proteins by enhanced chemiluminescence Western blotting using horseradish peroxidase and demonstrates that protein-bound polyphenols can be a source of “ghost” band artifacts on Western blots.

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Choline, Other Methyl-Donors and Epigenetics

Steven H. Zeisel (2017). Choline, Other Methyl-Donors and Epigenetics. Nutrients 9(445). Author Affiliations UNC Nutrition Research Institute, Departments of Nutrition and Pediatrics, University of North Carolina at Chapel Hill, 500 Laureate Drive, Kannapolis, NC 28081, USA; steven_zeisel@unc.edu; Tel.: +1-704-250-5006 Abstract Choline dietary intake varies such that many people do not achieve adequate intakes. Diet intake […]

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The role of gut microbiota on the metabolism of black tea theaflavins

Shuwei Zhang 1, Christina L Ohland 2, Christian Jobin 2 and Shengmin Sang 1 (2017). The role of gut microbiota on the metabolism of black tea theaflavins. The FASEB Journal 31(1). Author Affiliations 1 Laboratory for Functional Foods and Human Health, North Carolina A&T State University, Kannapolis, NC 2 University of Florida, Gainesville, FL Abstract […]

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Avenacosides: Metabolism, and potential use as exposure biomarkers of oat intake

Pei Wang, Junli Yang, Aaron Yerke, Shengmin Sang (2017). Avenacosides: Metabolism, and potential use as exposure biomarkers of oat intake. Molecular Nutrition & Food Research. Author Affiliations Laboratory for Functional Foods and Human Health, Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, Kannapolis, NC, USA Abstract Scope Exposure biomarkers used […]

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Signatures of anthocyanin metabolites identified in humans inhibit biomarkers of vascular inflammation in human endothelial cells

Emily F. Warner, Michael J. Smith, Qingzhi Zhang, K. Saki Raheem, David O’Hagan, Maria A. O’Connell, Colin D. Kay (2017). Signatures of anthocyanin metabolites identified in humans inhibit biomarkers of vascular inflammation in human endothelial cells. Molecular Nutrition & Food Research. Author Affiliations Department of Nutrition, Norwich Medical School, Bob Champion Research and Education Building, […]

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Monoolein aqueous dispersions as a delivery system for quercetin

Rita Cortesi, Enrica Cappellozza, Markus Drechsler, Catia Contado, Anna Baldisserotto, Paolo Mariani, Federica Carducci, Alessandra Pecorelli, Elisabetta Esposito, Giuseppe Valacchi (2017). Monoolein aqueous dispersions as a delivery system for quercetin. Biomedical Microdevices 19(41). Author Affiliations 1. Department of Life Sciences and Biotechnology University of Ferrara Ferrara Italy 2. BIMF / Soft Matter Electron microscopy University […]

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Avenanthramides and their microbial metabolites as the urinary exposure markers for whole grain oat intake: a kinetic study in humans

Shengmin Sang, Pei Wang and Aaron Yerke (2017). Avenanthramides and their microbial metabolites as the urinary exposure markers for whole grain oat intake: a kinetic study in humans. The FASEB Journal 31(1). Author Affiliations Laboratory for Functional Foods and Human Health, North Carolina A&T State University, Kannapolis, NC Abstract Oats are commonly consumed as whole […]

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Nutritional Changes During Biofortified Maize Fermentation (Steeping) for Ogi Production

Darwin Ortiz 1, Smith Nkhata 1, Aimee Buechler 1, Torbert Rocheford 2 and Mario G. Ferruzzi 3 (2017). Nutritional Changes During Biofortified Maize Fermentation (Steeping) for Ogi Production. The FASEB Journal 31(1). Author Affiliations 1 Department of Food Science, Purdue University, West Lafayette, IN 2 Department of Agronomy, Purdue University, West Lafayette, IN 3 Plants […]

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Dietary genistein inhibits methylglyoxal-induced advanced glycation end products formation in high-fat diet-fed mice

Yantao Zhao, Pei Wang and Shengmin Sang (2017). Dietary genistein inhibits methylglyoxal-induced advanced glycation end products formation in high-fat diet-fed mice. The FASEB Journal 31(1). Author Affiliations Laboratory for Functional Foods and Human Health, North Carolina A&T State University, Kannapolis, NC Abstract The formation and accumulation of advanced glycation end products (AGEs) was considered as […]

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Seven Day Blackberry Feeding Lowers the Respiratory Quotient in Males And Improves Insulin Sensitivity

Patrick Solverson 1,2, William Rumpler 1, Jayme L Leger 1, Benjamin Redan 3, Mario G Ferruzzi 4, David J Baer 1 and Janet A Novotny 1 (2017). Seven Day Blackberry Feeding Lowers the Respiratory Quotient in Males And Improves Insulin Sensitivity. The FASEB Journal 31(1). Author Affiliations 1 Beltsville Human Nutrition Research Center, USDA, Beltsville, […]

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Dietary Long-chain PUFAs Enrich Porcine Alveolar Macrophages and Alter Prostaglandin E2 Production Following LPS Challenge

Kathleen R Walter 1, Lin Xi 1, Sheila K Jacobi 2, Debora Esposito 3 and Jack Odle 1 (2017). Dietary Long-chain PUFAs Enrich Porcine Alveolar Macrophages and Alter Prostaglandin E2 Production Following LPS Challenge. The FASEB Journal 31 (1). Author Affiliations 1 Animal Science, North Carolina State University, Raleigh, NC 2 Animal Science, Ohio State […]

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Health Modifying Regions in the Oat (Avena sativa) Genome Responsible for Beneficial Effects on Immune and Gastrointestinal Health

Weston Woodrow Bussler 1,2, Katelyn Dezego 1,4, Mikayla Bowen 1,5, Ashley Buige 1,5, Debora Esposito 1,3, Mary Ann Lila 1,2 and Slavko Komarnytsky 1,2 (2017). Health Modifying Regions in the Oat (Avena sativa) Genome Responsible for Beneficial Effects on Immune and Gastrointestinal Health. The FASEB Journal 31(1). Author Affiliations 1 Plants for Human Health Institute, […]

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