Journal Articles

Trapping of glyoxal by propyl, octyl and dodecyl gallates and their mono-glyoxal adducts

July 12, 2018

Yu Houa, Zhengjun Xie, Hengqing Cuia Yongling Lu,Tiesong Zheng, Shengmin Sang, Lisuang Lv. Trapping of glyoxal by propyl, octyl and dodecyl gallates and their mono-glyoxal adducts. Food Chemistry. Volume 269, 15 December 2018, Pages 396-403 Received 22 April 2018, Revised 2 July 2018, Accepted 3 July 2018, Available online 4 July 2018.

Author Affiliation

A Department of Food Science and Technology, Nanjing Normal University, 122# Ninghai Road, Nanjing 210097, PR China

B Laboratory for Functional Foods and Human Health, Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus, 500 Laureate Way, Kannapolis, NC 28081, United States

C School of Food Science and Technology, Jiangnan University, 1800#, Lihu Road, Wuxi, Jiangsu 214122, PR China

Abstract

Glyoxal (GO) is one of the major toxic intermediates generated during lipid oxidation and degradation. We investigated the inhibitory activities and mechanisms of propyl, octyl, and dodecyl gallates (PG, OG, and DG) on the formation of GO in buffer and during thermo-processing of corn oil, and the anti-carbonyl and antioxidative activities of the mono-GO adducts of PG, OG, and DG. Our results suggested that alkyl gallates could more effectively trap GO than gallic acid. The major mono-GO adducts of PG, OG, and DG were purified and their structures were elucidated based on their 1H, 13C, 2D-NMR, and HRMS data. We further demonstrated that the mono-GO (MG) adducts retained the anti-carbonyl and antioxidative activities. This is the first study to demonstrate that alkyl gallates, the popular food additives, could prevent not only food oxidation, but also the formation of toxic reactive carbonyl species and their corresponding advanced glycation end products (AGEs) during food processing.

Comments are closed.

Connect With Us