Journal Articles

Research highlights from the Purdue-UAB Botanicals Research Center for Age-related Diseases

March 13, 2009

Weaver, Connie M., Steve Barnes, James M. Wyss, Helen Kim, D. M. Morre, D.J. Morre, James E. Simon, Mary Ann Lila, Elsa Janle and Mario Ferruzzi. 2009. Research highlights from the Purdue-UAB Botanicals Research Center for Age-related Diseases. Pharmceutical Biology 47: 768-773. PMID: 19890436.

Abstract

The Purdue-UAB Botanicals Research Center for Age Related Disease uses multidisciplinary and innovative technologies to investigate the bioavailability of bioactive polyphenolic constituents from botanicals and their relationship to human health. Many age-related diseases are associated with oxidative stress and tissue damage. One of the research goals of the Purdue-UAB Center is to investigate the bioavailability of bioactive natural compounds from a complex botanical mixture to the organ affected by the disease, determine the uptake and metabolism of these compounds and relate these data to a protective mechanism. Equally important is to screen commercially available botanicals for their safety and efficacy. The central aims of the Center include the investigation of botanicals and their relationship to bone antiresorptive capacity, cognitive function, vascular effects, and cancer prevention.

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