Journal Articles

Impact of Bioflavonoids from Berryfruits on Biomarkers of Metabolic Syndrome

December 15, 2010

Impact of Bioflavonoids from Berryfruits on Biomarkers of Metabolic Syndrome

Mary Ann Lila , Plants for Human Health Institute, North Carolina State University, 600 Laureate Way, Kannapolis, NC 28081, USA

Abstract
The phytochemical constituents which comprise many edible berry fruits have increasingly been
linked to modulation of biomarkers associated with conditions of diabetes, overweight/obesity,
and cardiovascular disease (CVD), all components of metabolic syndrome. While many wild
berries have long been valued in traditional medicine as health protective, it is only recently that
the ability of berry bioactives to affect particular clinical targets has been demonstrated. In
addition to the widely recognized antioxidant power of berry extracts, both commercial berry
varieties and wild species have been linked to hypoglycemic activity, inhibition of adipogenesis,
amelioration of CVD risk factors, anti-inflammatory capacity, and ability to induce
satiety/counteract overweight. In some cases, proanthocyanidin constituents or anthocyanin
pigments have been shown to be the active agents, but in many other cases, interactions between
co-occuring phytochemical constituents potentiate bioactivity of berry extracts.

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