Join a Study

At the NC Research Campus, scientists are continually recruiting participants for human clinical studies and focus groups. Review the studies that are currently recruiting below to find out if there is a study for you. To keep up with new studies as they become available, sign up for our e-mail alert.

Influence of 2-Weeks Flavonoid Supplementation and an Acute 45-Minute Walking Bout or 2.5 h Running Bout on Plasma Levels of Gut-Derived Phenolics

Principal Investigator: David C. Nieman, Human Performance Laboratory at the North Carolina Research Campus, Appalachian State University, Health, Leisure, Exercise Science.

What is the purpose of this research? A high intake (>2.5 cups per day) of fruits and vegetables is recommended for good health and disease prevention.  Many of the beneficial health effects liked to high diet intake of fruits and vegetables come from the purple, red, green, orange, and other colorful pigment molecules called flavonoids.  After consuming flavonoids, bacteria in your large intestine break them down into smaller molecules that can pass back into your blood and circulate through your body, producing healthful effects.  Running improves the transfer of the small flavonoid molecules from the colon back into your body, and this study (for the first time) will determine if a 45-minute brisk walk has a similar influence.

Why am I being invited to take part in this research? You will be one of 85 walkers and 25 runners in this study at the ASU-NCRC Human Performance Lab in Kannapolis, NC.  You are being invited to take part in this research if you are a healthy male or female, 18 to 50 years of age.  Walkers must have a regular history of walking (>100 minutes per week totaling all walking, both short or long duration episodes) and capable of walking 45 minutes briskly on a treadmill.  Runners must have a history of participating in 10 km to 42.2 km races and capable of running for 2.5 h on a treadmill.

What will I be asked to do? The research procedures will be conducted at the Human Performance Laboratory (Room 1201, Plants for Human Health Institute Building, 600 Laureate Way), operated by Appalachian State University at the North Carolina Research Campus (NCRC) in Kannapolis, NC.  You will need to come here four times, and the total amount of time you will be asked to volunteer for this study is about 5-6 hours.  You will also take a supplement twice daily (morning, noon), collect urine for 24 hours, provide four blood samples, and keep one 3-day food record.  Walkers (N=85) will be randomized to the flavonoid or placebo supplement groups for 2 weeks. You will report to the research facility for baseline testing (fitness testing for VO2max and body fat percent) and orientation (visit 1), at the start of supplementation (visit 2), after the 2-week supplementation period for the exercise or rest lab session (visit 3), and then again 24 hours later (visit 4).  During visit 3, you will be randomized to either sit or walk briskly on treadmills for 45 minutes.  A comparator group of 20-25 runners will ingest the flavonoid supplement for 2 weeks and then run 2.5 h on treadmills in the lab.

Will I be paid for taking part in the research? We will pay you $275 for the time you volunteer while being in this study.

How do I sign up for the study or obtain more information? Please send an email message to


Tobacco Study 

Study Purpose: This study will look at the effects of inhaled tobacco, from hookahs, vaping, and e-cigarettes.

Recruiting: Men and women ages 18-50 with no significant health problems, including asthma, chronic lung disease, cardiac disease, or any immune deficiencies. Woman who are pregnant should not participate

What You’ll Do: Visit the UNC NRI, in Kannapolis, NC, twice in a 6 week period. First visit for screening, second visit for blood draws and breathing test. Each visit lasts 1-3 hours. Eligible participants will be compensated $140. Additional $40 compensation to vapers, smokers, or hookah users completing a 4-week smoking diary.  Call 919-966-2879 or email for more information.

Fructose Study

Recruiting: African American, Hispanic and Caucasian participants
30 to 50 years old. Must be free of diabetes, fructose intolerance, and chronic kidney disease
What You’ll Do: Volunteers will come to the NRI (Kannapolis, NC) for approximately 3 hours, undergo an oral fructose challenge, fill out questionnaires, provide serial blood and urine samples
Study Purpose: High uric acid in the blood increases the risk of gout, kidney and heart disease. This study investigates whether each individual responds to sugar-sweetened beverages differently, due to their differing ethnicity and genetic backgrounds.
Eligible participants will be well-compensated once the study has been completed.
Get started today. Call 704-250-5060 or email

Fatty Liver Study

Study Purpose: To evaluate a new painless/non-invasive technique to study fatty liver disease.
Recruiting: 18 – 70 year olds with fatty liver disease.
What You’ll Do: Participants will volunteer for 2 days. Two non-invasive tests will be conducted to evaluate a known diagnosis of fatty liver disease. Each visit will take approximately 1 – 2 hours.
Eligible participants will receive $75 upon completion of each visit.
Call 704-250-5035 or email

Maternal and Child Health Study  

The UNC Nutrition Research Institute seeks to determine the effect of pregnancy complications in African American mothers on the disease risk of their children. Examples of pregnancy complications include high blood sugar, high blood pressure and preeclampsia.


  • African American mothers
  • Must be 18 years or older
  • With two or more children between ages 5-10
  • Mothers may or may not have had pregnancy complications

Volunteers will stay 1 to 2 hours to fill out questionnaires and provide blood, saliva and urine samples. See Details


Duke University in Kannapolis announces a new study opportunity, the COPD Study. Chronic Obstructive Pulmonary Disease, or COPD, is a progressive disease that makes it hard to breathe. Smoking is the most common cause of COPD. If you have been told you have emphysema, COPD or chronic bronchitis, you might qualify for this study. Compensation will be offered throughout the study.

To learn whether you qualify, call 704-250-5861, email or visit

The COPD Study is an observational study. Researchers will study the severity of COPD in 850 people and follow the progression of the disease over five years. The study will look at the correlation between a participant’s initial COPD status upon enrollment and the progression of symptoms during the study period.

People who qualify for the COPD study:

  • Are at least 40 years old
  • Have COPD (as determined during a study visit)
  • Are current or former heavy smokers

People who enrol l in the COPD study will be a sked to complete:

  • A phone screening
  • An in-person screening
  • A breathing test called spirometry
  • A medical questionnaire to document smoking history
  • A physical activity questionnaire
  • A 6-minute walk
  • Height and weight measurements

During five years of follow-up, participants will be asked to alternate between a study visit and a telephone interview every six months. The study aims to follow participants for five years; however, participants can withdraw at any time. Compensation will be provided throughout the study. Please share this opportunity with people you know who may qualify!





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