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Join a Study

At the NC Research Campus, scientists are continually recruiting participants for human clinical studies and focus groups. Review the studies that are currently recruiting below to find out if there is a study for you. To keep up with new studies as they become available, sign up for our e-mail alert.

Fructose Liver Fat Study

The UNC Nutrition Research Institute is recruiting Caucasian women ages 18-40 with no history of alcohol abuse for a study to identify genetic and dietary factors that affect the risk for non-alcoholic fatty liver disease. On the first visit participants will provide saliva samples. Selected participants will return to undergo an acute, and a 2-week oral fructose challenge for a total of three visits. Each visit, participants will provide blood, urine, and stool samples, as well as fill out a questionnaire. Participants will be compensated. Visit the NRI website for more details and to enroll.

Influence of Mixed Flavonoid Supplementation on Exercise-Induced Oxidative Stress, Inflammation, and Changes in Immune Function

Principal Investigator: David C. Nieman, Human Performance Laboratory at the North Carolina Research Campus, Appalachian State University, Health and Exercise Science.

What is the purpose of this research?
Prolonged and intensive exercise increases oxidative stress, inflammation, muscle damage, stress hormone levels, and immune dysfunction, and collectively represent exercise-induced physiological stress. Various nutritional products, including plant flavonoids, are being explored to attenuate post-exercise physiological stress. Flavonoids are a type of plant chemical found in fruits, green tea, vegetables, and other plant foods. These plant flavonoids may provide benefits for the athlete in improving body immune defenses against viruses and lessening the oxidative stress and inflammation that occurs following vigorous exercise bouts.

The PURPOSE of this study is to investigate the influence of 2-weeks mixed flavonoid versus placebo supplementation on your body’s immune system and oxidative stress and inflammation biomarkers after cycling exercise (75-kilometers) in 20 male and female study participants. Blood samples will be collected pre-supplementation, and then pre- and post-exercise (0-hours, 1.5-hours, 21-hours), with immune cells separated and analyzed for these biomarkers. We hypothesize that 2-weeks mixed flavonoid versus placebo supplementation will support immune function and lessen post-exercise increases in oxidative stress and inflammation.

Why am I being invited to take part in this research?
Participants will include 20 healthy male and female cyclists (ages 18-55 years) who regularly compete in road races (category 1 to 5) and are capable of cycling 75-km at race pace. To participate, you must agree to train normally, maintain body weight, and avoid the regular use of large-dose vitamin and mineral supplements, herbs, and medications that influence inflammation and immune function (especially Advil, Motrin, aspirin, and similar anti-inflammatory drugs) for the duration of the 6-week study.

What will I be asked to do?
The research procedures will be conducted at the Human Performance Laboratory (HPL) (Room 1201, Plants for Human Health Institute Building, 600 Laureate Way), operated by Appalachian State University at the North Carolina Research Campus (NCRC) in Kannapolis, NC. You will first come to the HPL for orientation and pre-study fitness tests including VO2max and body composition. You will be randomized to flavonoid or placebo groups, and take four capsules of the supplements each day for the first two weeks. You will report back to the HPL for your first 75-km cycling session, with blood samples taken before and immediately- and 1.5 hours after. You will report back to the HPL the following morning to provide another blood sample. This will be followed by a 2-week washout period, and then a repeat of all study procedures after crossing over to the opposite supplement group. Thus this study will entail six HPL visits. The total amount of time you will be asked to volunteer for this study is about 15 hours at the HPL (over a 6-week period).

Will I be paid for taking part in the research?
We will pay you $750 for the time you volunteer while being in this study.

How do I sign up for the study or obtain more information? Please send an email message to ASU-NCRC@appstate.edu or call 704-250-5352.

Another ASU Study

The ASU Human Performance Laboratory is also recruiting participants for:

 

Choline Status Study

Study Purpose: The purpose of this study is to determine which biomarkers in the blood most accurately reflect choline status. Choline is an important nutrient in human diet.

What participants will do: To do this, volunteer subjects will be placed on a low choline diet for two weeks, followed by a two week washout, and then another two weeks on a diet containing adequate choline levels. We will provide all your meals for the 4 weeks (28 days) spent on the low choline and adequate choline diets, and you must not eat or drink any other foods during those weeks. We will take blood and urine samples at various times throughout the study to examine various markers and determine how they are changed by dietary choline levels.

Recruiting: Healthy males and females between ages of 17-70 years of age.
To participate your weight must be between 132-177 lbs.

Compensation: Eligible participants will be compensated for their time and payments will be reported to the IRS as income unless you choose to participate without compensation. The amount is $750 for completing the study
Get started today! Call 704-250-5035/5062 or email us at hrc_studies@unc.edu

 

Diet and the Gut Microbiome Study

Study Purpose: The purpose of this study is to identify individual differences in metabolite production after the intake of specific foods, which provide important nutrients for the body.

What participants will do: Study activities will occur over 4 days. Volunteer subjects will consume a standard diet for the first two days of the study. It is important that participants only eat foods provided by the study for these two days. On the first study day, participants will come to the Nutrition Research Institute (NRI) to receive their study materials, complete study surveys, and provide a saliva sample. We estimate that this visit will take about two hours. Participants will complete study activities in their home for the remainder of day one and day two. On the third study day, participants will consume dietary supplements in the morning along with a standard diet for the day, and collect all urine over the following 24-hours. On day four of the study, participants will return their urine samples to the NRI. Participants will also provide a stool sample.

Recruiting: Healthy males and females between ages of 18-70 years of age. Exclusions: No smoking, known food allergies, history of chronic medical illness, antibiotic use in last three months

Compensation: Eligible participants will be compensated for their time. The amount is $200 for completing the study.

Get started today! Call 704-250-5044 or email us at gutmicrobiome@unc.edu

 

Project Baseline

Project Baseline is a long-term quest to map human health.  The Project Baseline study, launched in 2017, is the first initiative of Project Baseline and is a collaboration among teams at Verily, Duke University School of Medicine, Stanford Medicine, and Google.

Compensation: Offered throughout the study, which will follow participants for at least four years.

Interested in enrolling? To learn more and consider joining this exciting endeavor, visit www.projectbaseline.com or call 855-5-BASELINE (855-522-7354).

How long will the Project Baseline study last? How many people will enroll?

The Project Baseline study is an observational study that will collect, organize, and analyze broad health data from approximately 10,000 participants over the course of at least four years.

Who can participate in the Project Baseline study?

Participants must be at least 18 years old, residents of the United States, able to speak and read English or Spanish, and not severely allergic to nickel or metal jewelry.

What is the Project Baseline study trying to find out?

The study is designed to develop a well-defined reference, or “baseline,” of good health, as well as a rich data platform that may be used to better understand the transition from health to disease. Participants will join together with a team of experts from across academia, medicine, science, technology, engineering, and design to better understand how health can change over time. Participants will be asked to visit a study site up to four times yearly, test new technologies and wearable devices daily, and participate in interactive surveys and diaries by using a smartphone, computer, or call center. Data collected will include clinical, imaging, self-reported, physical, environmental, behavioral, sensor, molecular, genetic, and other health-related measurements. Biospecimens collected will include blood and saliva, among others.

Want to know more? Visit www.projectbaseline.com

 

Maternal and Child Health Study  

The UNC Nutrition Research Institute seeks to determine the effect of pregnancy complications in African American mothers on the disease risk of their children. Examples of pregnancy complications include high blood sugar, high blood pressure and preeclampsia.

Recruiting:

  • African American mothers
  • Must be 18 years or older
  • With two or more children between ages 5-10
  • Mothers may or may not have had pregnancy complications

Volunteers will stay 1 to 2 hours to fill out questionnaires and provide blood, saliva and urine samples. See Details.

 

 

 

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