Steven H. Zeisel

Feasibility and Acceptability of Maternal Choline Supplementation in Heavy Drinking Pregnant Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

June 21, 2018

Jacobson SW1,2,3, Carter RC4,5, Molteno CD3, Meintjes EM2,6, Senekal MS7, Lindinger NM2, Dodge NC1, Zeisel SH8, Duggan CP9, Jacobson JL1,2,3. Feasibility and Acceptability of Maternal Choline Supplementation in Heavy Drinking Pregnant Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Alcohol Clin Exp Res. 2018 May 11. doi: 10.1111/acer.13768. 1 Department of Psychiatry and Behavioral Neurosciences , Wayne State University School of Medicine, Detroit, Michigan. 2 Department of Human […]

Efficacy of Maternal Choline Supplementation During Pregnancy in Mitigating Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

June 21, 2018

Jacobson SW1,2,3, Carter RC4,5, Molteno CD3, Stanton ME6, Herbert JS7, Lindinger NM2, Lewis CE2, Dodge NC1, Hoyme HE8,9, Zeisel SH10, Meintjes EM2,11, Duggan CP12, Jacobson JL1,2,3Efficacy of Maternal Choline Supplementation During Pregnancy in Mitigating Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.  Alcohol Clin Exp Res. 2018 May 11. doi: 10.1111/acer.13769. 1 Department of Psychiatry and Behavioral Neurosciences, Wayne State […]

Joint Life Science Caucus Visits the NC Research Campus

April 06, 2018

The original story was published by NCBIO. The Legislative Life Science Caucus members heard about nutrition and physiology research under way at the North Carolina Research Campus, which is celebrating its 10th anniversary. Presenters from Appalachian State University, told lawmakers the “Collaborative Approach to Human Performance Research” that it is undertaking with support from North […]

Dietary Modulation of the Epigenome

February 22, 2018

Folami Y. Ideraabdullah and Steven H. Zeisel (2018). Dietary Modulation of the Epigenome. Physiological Reviews 98(2), 667-695. Abstract Epigenetics is the study of heritable mechanisms that can modify gene activity and phenotype without modifying the genetic code. The basis for the concept of epigenetics originated more than 2,000 yr ago as a theory to explain […]

Contribution of Dietary Supplements to Nutritional Adequacy by Socioeconomic Subgroups in Adults of the United States

January 04, 2018

Jeffrey B. Blumberg, Balz Frei, Victor L. Fulgoni III, Connie M. Weaver and Steven H. Zeisel (2018). Contribution of Dietary Supplements to Nutritional Adequacy by Socioeconomic Subgroups in Adults of the United States. Nutrients, 10(1), 4. Author Affiliations Antioxidants Research Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, and the Friedman School of […]

Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups

December 14, 2017

Jeffrey B. Blumberg, Balz Frei, Victor L. Fulgoni, Connie M. Weaver and Steven H. Zeisel (2017). Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups. Nutrients 9(12). Author Affiliations: Antioxidants Research Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, and the Friedman School of Nutrition Science and Policy, Tufts University, […]

Choline: The essential but forgotten nutrient

December 14, 2017

This article was originally published November 2, 2017 in The Seattle Times. by Carrie Dennent Special to The Seattle Times On Nutrition Perhaps it’s because you don’t see it on nutrition labels yet, but choline — an essential nutrient from conception through old age — tends to be tragically overlooked. According to data from the National Health […]

What’s Essential for the Prenatal Brain?

October 27, 2017

This interview was originally published in Carolina Public Health Magazine – Fall 2017. Steven H. Zeisel, MD, PhD, Kenan Distinguished University Professor of Nutrition and Pediatrics, and Director, UNC Nutrition Research Institute, Kannapolis, NC In science, 10 percent of successful scientific discovery is the result of skill and hard work – but 90 percent comes from asking the […]

Impact of Frequency of Multi-Vitamin/Multi-Mineral Supplement Intake on Nutritional Adequacy and Nutrient Deficiencies in U.S. Adults

August 17, 2017

Jeffrey B. Blumberg, Balz B. Frei, Victor L. Fulgoni III, Connie M. Weaver and Steven H. Zeisel (2017). Impact of Frequency of Multi-Vitamin/Multi-Mineral Supplement Intake on Nutritional Adequacy and Nutrient Deficiencies in U.S. Adults. Nutrients 9(8) 849. Author Affiliations 1 Antioxidants Research Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging and Friedman School […]

Reduced brain volume and impaired memory in betaine homocysteine S-methyltransferase knockout mice

July 27, 2017

Emily A.K. Prieur , Eneda Pjetri, Steven H. Zeisel, Nafisa M Jadavji (2017). Reduced brain volume and impaired memory in betaine homocysteine S-methyltransferase knockout mice. Applied Physiology, Nutrition, and Metabolism. Abstract Using a mouse model, this study examined the impact of lack of betaine homocysteine S-methyltransferase (BHMT) on neurological function. Bhmt-/- mice maintained on a […]

Choline Builds Healthy Eyes

July 13, 2017

Read the original article by Tom Druke from Natural Products Insider. The eye health segment appears to be undergoing a solid resurgence over the past few years. According to data from Innova Market Insights, global new product launches with “vision” claims more than doubled from 2015 to 2016, and remain on pace to maintain that […]

precision nutrition

Precision Nutrition Needed for Healthy Military Muscles

June 22, 2017

Read the original article by Allan Maurer from the North Carolina Biotechnology Center. Eat colorful meals and make sure you get enough choline. That’s the key advice two nutrition experts offered during lunch at the Medical, BioMedical & BioDefense: Support the Warfighter symposium in Chapel Hill last week. The North Carolina Biotechnology Center’s Bio Defense […]

Deletion of one allele of Mthfd1 (methylenetetrahydrofolate dehydrogenase 1) impairs learning in mice

June 08, 2017

Eneda Pjetria, Steven H. Zeisel (2017). Deletion of one allele of Mthfd1 (methylenetetrahydrofolate dehydrogenase 1) impairs learning in mice. Behavioural Brain Research 332(71-74). Author Affiliations a Nutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, NC 28081, United States b Department of Nutrition, Gillings Global School of Public Health, University of North Carolina […]

Astronaut ophthalmic syndrome

June 01, 2017

Sara R. Zwart*, Charles R. Gibson†, Jesse F. Gregory‡, Thomas H. Mader§,1, Patrick J. Stover¶, Steven H. Zeisel‖ and Scott M. Smith (2017). Astronaut ophthalmic syndrome. The FASEB Journal. Author Affiliations *Department of Preventive Medicine and Community Health, University of Texas Medical Branch, Galveston, Texas, USA; †Coastal Eye Associates, Webster, Texas, USA; ‡Food Science and […]

Choline, Other Methyl-Donors and Epigenetics

May 25, 2017

Steven H. Zeisel (2017). Choline, Other Methyl-Donors and Epigenetics. Nutrients 9(445). Author Affiliations UNC Nutrition Research Institute, Departments of Nutrition and Pediatrics, University of North Carolina at Chapel Hill, 500 Laureate Drive, Kannapolis, NC 28081, USA; steven_zeisel@unc.edu; Tel.: +1-704-250-5006 Abstract Choline dietary intake varies such that many people do not achieve adequate intakes. Diet intake […]

NCRC Science Stop is a New Addition at Jiggy with a Piggy

May 02, 2017

Kannapolis, NC- The annual Jiggy with a Piggy Festival is this weekend in downtown Kannapolis. Scientists and staff from the research centers at the NC Research Campus are joining the fun on Saturday, May 6 from 10 am to 2 pm at the NCRC Science stop. Children and their families will find the Science Stop […]

“Put Your Best Fork Forward” at Events Sponsored by NCRC Partners

March 02, 2017

  Programs offered by experts at the NC Research Campus help people “Put their Best Fork Forward” in March during National Nutrition Month. Kannapolis, NC – “Put Your Best Fork Forward” is the theme of this year’s National Nutrition Month celebration. Sponsored annually in March by The Academy of Nutrition and Dietetics, this year’s theme is […]