FOCUS AREAS

New Approaches to Cancer Prevention and Treatment

picMeet the NC Research Campus scientists below who are involved with cancer-related research that focuses on the preventative and therapeutic value of nutrients and bioactive compounds in fruits, vegetables and grains. Learn more about each of the scientists and their institutes by using the links below. To the right, read the most recent journal articles and headlines on cancer research at the NC Research Campus.

Leading Cancer Researchers

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Stephen Hursting, PhD, MPH, is a professor of nutrition with the UNC Chapel Hill Nutrition Research Institute, who researches diet-gene interactions relevant to cancer prevention, particularly the molecular and hormonal mechanisms underlying energy balance-cancer associations. Learn more.

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Natalia Krupenko, PhD, assistant professor of nutrition with the UNC Chapel Hill Nutrition Research Institute, is focused on the role of folate (vitamin B9) in human health and disease. Folate deficiency has been connected with increased risk for neural tube defects, cardiovascular disease and some cancers. She also studies the risks of over supplementation. Learn more.

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Sergey Krupenko, PhD, professor of nutrition with the UNC Chapel Hill Nutrition Research Institute, investigates the vitamin folate and its role in liver function and cancer disease. His goal is to understand how cancer can be fought by controlling diet and nutrient supplements in ways that can activate resistance to tumor formation or slow down cancer development. Learn more.

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TinChung Leung, PhD, is with the NC Central University Nutrition Research Program. He uses a zebrafish model as the basis for his research into the molecular mechanisms of blood vessel development as it relates to cancer and cardiovascular disease. The zebrafish model is also used to validate therapeutic compounds including drug-like small molecules and bioactive compounds from natural products. Learn more.

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Shengmin Sang, PhD, associate professor specializing in functional foods with the NCA&T Center for Post-Harvest Technologies, researches preventative and therapeutic measures for chronic diseases like cancer and diabetes by using metabolomics to identify dietary exposure markers and bioactive compounds in foods like ginger and whole grains that have therapeutic potential. Learn more.

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Xiaohe Yang, PhD, associate professor with the North Carolina Central University Nutrition Research Program, researches dietary and hormonal modulation in relationship to breast cancer risk and prevention. He specifically focuses on erbB-2/Her2 breast cancer, which is a group of more aggressive breast cancers caused by the overexpression of the Her2 tumor protein. Read more about his research into soy and the isoflavone genistein. Learn more.

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Zhanxiang Zhou, PhD, co-director of the UNC Greensboro Center for Translational Biomedical Research, is an expert in the field of alcohol-induced fatty liver disease (AFLD), a cause of liver cancer. His research has uncovered organ-organ mechanisms and dietary deficiencies that underlie the cause of AFLD as well as dietary interventions such as zinc supplementation that prevent and, in an animal model, reversed AFLD-caused liver damage. Learn more.

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